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个人简介

Trevor has been Professor of Cognitive Neuroscience at the University of Cambridge from 1997. He was also Professor of Expt. Psychology and Head of the Dept. of Psychology from 2002-2017. He has been based in Cambridge for most of his scientific career, receiving his PhD there in 1975. He is a Fellow of the British Psychological Society (1990), the British Pharmacological Society (2017) the Academy of Medical Sciences (2000), and the Royal Society (2005), the most prestigious science society in the U.K. He has published over 800 full papers, with an H index of about 179. He has co-edited eight books, most recently Translational Neuropsychopharmacology (Springer, 2016)). He edits Psychopharmacology (since 1980) and Current Opinion in the Behavioral Sciences and is an editorial advisor for Science.Trevor directs the ‘Behavioural and Clinical Neuroscience Institute’ (BCNI) (founded in 2005 with funding from the MRC and Wellcome Trust) the mission of which is to enhance translation from basic to clinical neuroscience with particular reference to impulsive-compulsive disorders including drug addiction. His interest in translation began with his co-invention in 1987 of the CANTAB computerized neuropsychological battery, which is currently used in over 700 institutes and clinical centres world-wide. Among several prizes, he received the Distinguished Scientific Contribution Award for 2011 from the American Psychological Association. He was made a CBE in the New Year’s Honours list of the U.K. in 2012 "for services to medical research". In 2014 he shared the ‘Brain Prize’ of the Grete Lundbeck European Brain Research Foundation, the most valuable in neuroscience, for his work on human mental disorders. In 2015 he received the “Lifetime Achievement Award” of the British Association for Psychopharmacology’. In 2016, he received the Robert Sommer Award for research into schizophrenia. In 2017 received the Gold Medal of the Society for Biological Psychiatry (USA) for work on cortico-striatal systems and their modulation, and, most recently, the Patricia Goldman-Rakic Award for outstanding research in Cognitive Neuroscience.

研究领域

Cognitive and Behavioural Neuroscience, Neuropsychology and Psychopharmacology

近期论文

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Aron, A.R., Fletcher, P.C., Bullmore, E.T., Sahakian, B.J. & Robbins, T.W. (2003) Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans. Nature Neuroscience, 6, 115-116. Aron, A.R., Robbins, T.W. & Poldrack, R.A. (2004) Inhibition and the right inferior frontal cortex. Trends in Cognitive Sciences, 8, 170-177. Ito, R., Robbins, T.W. & Everitt, B.J. (2004) Differential control over cocaine-seeking behavior by nucleus accumbens core and shell. Nature Neuroscience, 7, 389-397. Clarke, H.F., Dalley, J.W., Crofts, H.S., Robbins, T.W. & Roberts, A.C. (2004) Cognitive inflexibility after prefrontal serotonin depletion. Science, 304, 878-880. Robbins, T.W. (2005) Chemistry of the mind: neurochemical modulation of prefrontal cortical function. Journal of Comparative Neurology, 493, 140-146. (Review) Everitt, B.J. & Robbins, T.W. (2005) Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nature Neuroscience, 8, 1481-1489. (Review) Chamberlain, S.R., Müller, U., Blackwell, A.D., Clark, L., Robbins, T.W. & Sahakian, B.J. (2006) Neurochemical modulation of response inhibition and probabilistic learning in humans. Science, 311, 861-863. Dalley, J.W., Fryer, T.D., Brichard, L., Robinson, E.S.J., Theobald, D.E.H., Lääne, K., Peña, Y., Murphy, E.R., Shah, Y., Probst, K., Abakumova, I., Aigbirhio, F.I., Richards, H.K., Hong, Y., Baron, J.C., Everitt, B.J., Robbins, T.W. (2007) Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science, 315, 1267-1270. Robbins, T.W. (2007) Shifting and stopping: fronto-striatal substrates, neurochemical modulation and clinical implications. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 362, 917-932. (Review) Belin, D., Mar, A.C., Dalley, J.W., Robbins, T.W. & Everitt, B.J. (2008) High impulsivity predicts the switch to compulsive cocaine-taking. Science, 320, 1352-1355. Crockett, M.J., Clark, L., Tabibnia, G., Lieberman, M.D. & Robbins, T.W. (2008) Serotonin modulates behavioural reactions to unfairness. Science, 320, 1739. Chamberlain, S.R., Menzies, L., Hampshire, A., Suckling, J., Fineberg, N.A., del Campo, N., Aitken, M.R.F., Craig, K., Owen, A.M., Bullmore, E.T., Robbins, T.W. & Sahakian, B.J. (2008) Orbitofrontal dysfunction in patients with obsessive-compulsive disorder and their unaffected relatives. Science, 321, 421-422. Robbins, T.W. & Arnsten, A.F.T. (2009) The neuropsychopharmacology of fronto-executive function: monoaminergic modulation. Annual Review of Neuroscience, 32, 267-287. (Review) Crockett, M.J., Clark, L., Hauser, M.D. & Robbins, T.W. (2010) Serotonin selectively influences moral judgment and behavior through effects on harm aversion. Proceedings of the National Academy of Sciences, USA, 107, 17433-17438. Ersche, K.D., Bullmore, E.T., Craig, K.J., Shabbir, S.S., Abbott, S., Müller, U., Ooi, C., Suckling, J., Barnes, A., Sahakian, B.J., Merlo-Pich, E.V. & Robbins, T.W. (2010) Influence of compulsivity of drug abuse on dopaminergic modulation of attentional bias in stimulant dependence. Archives of General Psychiatry, 67, 632-644. Kehagia, A.A., Barker, R.A. & Robbins, T.W. (2010) Neuropsychological and clinical heterogeneity of cognitive impairment and dementia in Parkinson’s disease. The Lancet Neurology, 9, 1200-1213. (Review) Indovina, I., Robbins, T.W., Núñez-Elizalde, A.O., Dunn, B.D. & Bishop, S.J. (2011) Fear-conditioning mechanisms associated with trait vulnerability to anxiety in humans. Neuron, 69, 563-571 Dalley, J.W., Everitt, B.J. & Robbins, T.W. (2011) Impulsivity, compulsivity, and top-down cognitive control. Neuron, 69, 680-694. (Review) Gillan, C.M., Papmeyer, M., Morein-Zamir, S., Sahakian, B.J., Fineberg, N.A., Robbins, T.W. & de Wit, S. (2011) Disruption in the balance between goal-directed behaviour and habit learning in obsessive-compulsive disorder. American Journal of Psychiatry, 168, 718-726. Robbins, T.W., Gillan, C.M., Smith, D.G., de Wit, S. & Ersche, K.D. (2012) Neurocognitive endophenoypes of impulsivity and compulsivity: towards dimensional psychiatry. Trends in Cognitive Sciences, 16, 81-91 (Review). Ersche, K.D., Jones, P.S., Williams, G.B., Turton, A.J., Robbins, T.W. & Bullmore, E.T. (2012) Abnormal brain structure implicated in stimulant drug addiction. Science, 335, 601-604. Blakemore, S.J. & Robbins, T.W. (2012) Decision-making in the adolescent brain. Nature Neuroscience, 15, 1184-1191. Ersche, K.D., Jones, P.S., Williams, G.B., Smith, D.G., Bullmore, E.T. & Robbins, T.W. (2013) Distinctive personality traits and neural correlates associated with stimulant drug use versus familial risk of stimulant dependence. Biological Psychiatry, 74, 137-44. Crockett, M.J., Braams, B.R., Clark, L., Tobler, P.N., Robbins, T.W. & Kalenscher, T. (2013) Restricting temptations: neural mechanisms of precommitment. Neuron, 79(2), 391-401. Bari, A. & Robbins, T.W. (2013) Inhibition and impulsivity: behavioral and neural basis of response control. Progress in Neurobiology, 108, 44-79. Besson, M., Pelloux, Y., Dilleen, R., Theobald, D.E., Lyon, A., Belin-Rauscent, A., Robbins, T.W., Dalley, J.W., Everitt, B.J. & Belin, D. (2013) Cocaine modulation of fronto-striatal expression of zif268, D2 and 5-HT2c receptors in high and low impulsive rats. Neuropsychopharmacology, 38(10), 1963-73. Voon, V., Irvine, M.A., Derbyshire, K., Worbe, Y., Lange, I., Abbott, S., Morin-Zamir, S., Dudley, R., Caprioli, D., Harrison, N.A., Wood, J., Dalley, J.W., Bullmore, E.T., Grant, J.E. & Robbins, T.W. (2013) Measuring “waiting” impulsivity in substance addictions and binge eating disorder in a novel analogue of the rodent serial reaction time task. Biological Psychiatry, 75(2),148-55. Caprioli, D., Sawiak, S.J., Merlo, E., Theobald, D.E., Spoelder, M., Jupp, B., Voon, V., Carpenter, T.A., Everitt, B.J., Robbins, T.W. & Dalley, J.W. (2013) Gamma aminobutyric acidergic and neuronalstructural markers in the nucleus accumbens core underlie trait-like impulsive behaviour. Biological Psychiatry, 75(2), 115-23. Gillan, C.M., Morein-Zamir, S., Urcelay, G.P., Sule, A., Voon, V., Apergis-Schoute, A.M., Fineberg, N.A., Sahakian, B.J. & Robbins, T.W. (2014) Enhanced avoidance habits in obsessive-compulsive disorder. Biological Psychiatry, 75(8), 631-8. Fernando, A., Urcelay, G., Mar, A., Dickinson, A., Robbins, T. (2014) Free-operant avoidance behavior by rats after reinforcer revaluation using opioid agonists and D-amphetamine. Journal of Neuroscience, 34(18), 6286-93. Kehagia AA, Housden CR, Regenthal R, Barker RA, Müller U, Rowe J, Sahakian BJ, Robbins TW. (2014) Targeting impulsivity in Parkinson's disease using atomoxetine. Brain, 137(Pt 7), 1986-97. Eisenegger C, Naef M, Linssen A, Clark L, Gandamaneni PK, Müller U, Robbins TW. (2014) Role of dopamine D2 receptors in human reinforcement learning. Neuropsychopharmacology, 39(10), 2366-2375 Gillan, C.M., Robbins, T.W. (2014) Goal-directed learning and obsessive-compulsive disorder.Philosophical Transactions of the Royal Society of London. Series B, Biological sciences, 369(1655). pii:20130475. Rygula, R., Clarke, H.F., Cardinal, R.N., Cockcroft, G.J., Xia, J., Dalley, J.W., Robbins, T.W., Roberts, A.C. (2014) Role of central serotonin in anticipation of rewarding and punishing outcomes: effects of selective amygdala or orbitofrontal 5-HT depletion. Cerebral Cortex, 25(9):3064-76. Voon, V., Derbyshire, K., Rück, C., Irvine, M.A., Worbe, Y., Enander, J., Schreiber, L.R., Gillan, C.,Fineberg, N.A., Sahakian, B.J., Robbins, T.W., Harrison, N.A., Wood, J., Daw, N.D., Dayan, P., Grant, J.E., Bullmore, E.T. (2015) Disorders of compulsivity: a common bias towards learning habits. Molecular Psychiatry, 20(3), 345-52. Giuliano, C., Goodlett, C.R., Economidou, D., García-Pardo, M.P., Belin, D., Robbins, T.W., Bullmore, E.T., Everitt, B.J. (2015) The novel μ-opioid receptor antagonist GSK1521498 decreases both alcohol seeking and drinking: evidence from a new preclinical model of alcohol seeking. Neuropsychopharmacology, 40(13), 2981-92. Everitt, B.J. & Robbins, T.W. (2016) Drug Addiction: Updating Actions to Habits to Compulsions Ten Years On. Annual Review of Psychology, 67, 23-50. Barnett JH, Blackwell AD, Sahakian BJ, Robbins TW. (2016) The Paired Associates Learning (PAL) Test: 30 years of CANTAB Translational Neuroscience from Laboratory to Bedside in Dementia Research. Curr Top Behav Neurosci., 28, 449-74. Ersche KD, Gillan CM, Jones PS, Williams GB, Ward LH, Luijten M, de Wit S, Sahakian BJ, Bullmore ET, Robbins TW. (2016) Carrots and sticks fail to change behavior in cocaine addiction. Science, 352(6292), 1468-71. Dalley JW, Robbins TW. (2017) Fractionating impulsivity: neuropsychiatric implications. Nat Rev Neurosci.,18(3), 158-171. Apergis-Schoute AM, Gillan CM, Fineberg NA, Fernandez-Egea E, Sahakian BJ, Robbins TW. (2017) Neural basis of impaired safety signaling in Obsessive Compulsive Disorder. Proc Natl Acad Sci U S A. 114(12), 3216-3221. Vaghi MM, Vértes PE, Kitzbichler MG, Apergis-Schoute AM, van der Flier FE, Fineberg NA, Sule A, Zaman R, Voon V, Kundu P, Bullmore ET, Robbins TW. (2017) Specific Frontostriatal Circuits for Impaired Cognitive Flexibility and Goal-Directed Planning in Obsessive-Compulsive Disorder: Evidence From Resting-State Functional Connectivity. Biol Psychiatry, 81(8), 708-717. Robbins TW, Costa RM. (2017) Habits. Curr Biol., 27(22), R1200-R1206. Vaghi MM, Luyckx F, Sule A, Fineberg NA, Robbins TW, De Martino B. (2017) Compulsivity Reveals a Novel Dissociation between Action and Confidence. Neuron. 96(2), 348-354. Zmigrod L, Rentfrow J and Robbins TW (2018) Cognitive underpinnings of nationalistic ideology in the context of Brexit. Proc. Natl. Acd. Sci. USA 115(19):E4532-E4540

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