个人简介
Dr. Indira Prasadam obtained her PhD degree from Queensland University of Technology. Her training has had a special focus on bone and cartilage related disorders, chiefly osteoarthritis as well as osteoporosis disorders. After a PhD degree in Cell & Molecular biology she is currently working as a post-doctoral research fellow in QUT. She supervised three international exchange students, 1 occupational trainee and currently supervising 2 PhD students in QUT. Her research projects have attracted research funding from various competitive grant schemes.
研究领域
* Developing disease modifying drugs for osteoarthritis therapy and prevention
* Role of subchondral bone in osteoarthritis
Cross-talk of bone and cartilage
Osteoarthritic animal models
Role of signalling pathways in osteoarthritis
* Role of miRNAs in osteoarthritis
近期论文
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Prasadam, Indira, Batra, Jyotsna, Perry, Samuel, Gu, Wenyi, Crawford, Ross, & Xiao, Yin (2016) Systematic identification, characterization and target gene analysis of microRNAs involved in osteoarthritis subchondral bone pathogenesis. Calcified Tissue International, 99(1), pp. 43-55.
Gu, Wenyi, Prasadam, Indira, Yu, Meihua, Zhang, Fengxia, Ling, Patrick, Xiao, Yin, et al. (2015) Gamma tocotrienol targets tyrosine phosphatase SHP2 in mammospheres resulting in cell death through RAS/ERK pathway. BMC Cancer, 15, Article 609.
Zhou, Yinghong, Fan, Wei, Prasadam, Indira, Crawford, Ross, & Xiao, Yin (2015) Implantation of osteogenic differentiated donor mesenchymal stem cells causes recruitment of host cells. Journal of Tissue Engineering and Regenerative Medicine, 9(2), pp. 118-126.
Afara, Isaac O., Moody, Hayley, Singh, Sanjleena, Prasadam, Indira, & Oloyede, Adekunle (2015) Spatial mapping of proteoglycan content in articular cartilage using near-infrared (NIR) spectroscopy. Biomedical Optics Express, 6(1), pp. 144-154.
Prasadam, Indira, Zhou, Yinghong, Shi, Wei, Crawford, Ross, & Xiao, Yin (2014) Role of dentin matrix protein 1 in cartilage redifferentiation and osteoarthritis. Rheumatology, 53(12), pp. 2280-2287.
Wei, Lingfei, Ke, Jin, Prasadam, Indira, Miron, Richard J., Lin, Shirao, Xiao, Yin, et al. (2014) A comparative study of Sr-incorporated mesoporous bioactive glass scaffolds for regeneration of osteopenic bone defects. Osteoporosis International, 25(8), pp. 2089-2096.
Afara, Isaac Oluwaseun, Prasadam, Indira, Moody, Hayley, Crawford, Ross W., Xiao, Yin, & Oloyede, Adekunle (2014) Near infrared spectroscopy for rapid determination of Mankin score components : a potential tool for quantitative characterization of articular cartilage at surgery. Arthroscopy : The Journal of Arthroscopic & Related Surgery, 30(9), pp. 1146-1155.
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