个人简介
Associate Professor Travis Klein is an ARC Future Fellow who heads the Cartilage Regeneration Laboratory (CRL) and the Orthopaedics, Trauma & Emergency Care Program at the Institute of Health and Biomedical Innovation. The ultimate goal of the CRL is to help develop long-term regenerative therapies for treating cartilage defects, including osteoarthritis. To help understand chondrogenesis and joint pathologies, and engineer functional tissues, the group is developing:
model systems using human cells
functionalised biomaterials
biofabrication approaches
mechanical stimulation technologies
近期论文
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Levett PA, Melchels FP, Schrobback K, Hutmacher D, Malda J, Klein TJ, (2014) A biomimetic extracellular matrix for cartilage tissue engineering centered on photocurable gelatin, hyaluronic acid and chondroitin sulfate, Acta Biomaterialia p214-223
Schuurman W, Levett PA, Pot MW, Van Weeren P, Dhert WJ, Hutmacher D, Melchels FP, Klein TJ, Malda J, (2013) Gelatin-methacrylamide hydrogels as potential biomaterials for fabrication of tissue-engineered cartilage constructs, Macromolecular Bioscience p551-561
Schrobback K, Wrobel J, Hutmacher D, Woodfield TB, Klein TJ, (2013) Stage-specific embryonic antigen-4 Is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells, Tissue Engineering Part A: Tissue Engineering p1316-1326
Melchels F, Domingos MA, Klein T, Malda J, Bartolo PJ, Hutmacher D, (2012) Additive manufacturing of tissues and organs, Progress in Polymer Science p1079-1104
Schrobback K, Malda J, Crawford R, Upton Z, Leavesley D, Klein T, (2012) Effects of oxygen on zonal marker expression in human articular chondrocytes, Tissue Engineering, Part A p920-933
Schrobback K, Klein TJ, Schuetz M, Upton Z, Leavesley DI, Malda J, (2011) Adult human articular chondrocytes in a microcarrier-based culture system: expansion and redifferentiation, Journal of Orthopaedic Research p539-546
Benders K, Malda J, Saris DB, Dhert W, Steck R, Hutmacher D, Klein TJ, (2010) Formalin fixation affects equilibrium partitioning of an ionic contrast agent-microcomputed tomography (EPIC-uCT) imaging of osteochondral samples, Osteoarthritis and Cartilage p1586-1591
Klein TJ, Rizzi SC, Schrobback K, Reichert J, Jeon J, Crawford RW, Hutmacher D, (2010) Long-term effects of hydrogel properties on human chondrocyte behavior, Soft Matter p5175-5183
Klein TA, Rizzi SC, Reichert JC, Georgi N, Malda J, Schuurman W, Crawford RW, Hutmacher D, (2009) Strategies for zonal cartilage repair using hydrogels, Macromolecular Biosciences p1049-1058
Klein TA, Malda J, Sah RL, Hutmacher D, (2009) Tissue engineering of articular cartilage with biomimetic zones., Tissue Engineering. Part B. Reviews p143-157