Trapani, Giovanna Di - Griffith University - School of Natural Sciences

研究领域

My research interest is mainly focused on the thioredoxin system, a key antioxidant defence system that protects cells from the damage caused by reactive oxygen species (ROS) and that has been implicated in many cellular processes. Currently we are investigating the role mediated by thioredoxin and thioredoxin reductase in cancer cells under hypoxic stress and the cross talk between the hypoxic and redox systems in the cancer cell environment. Development and implementation of innovative and non-traditional practices of teaching and learning in laboratory courses, including the use of blended learning methodology, a combination of traditional practice of teaching and technology based material in laboratory courses.

近期论文

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Prahlad V. Raninga, Giovanna Di Trapani, Kathryn F. Tonissen. Cross-talk between two antioxidant systems, Thioredoxin and DJ-1: consequences for cancer. Oncoscience, (2014), 1 (1), 95-110. Maneet Bhatia, Therese C. Karlenius, Giovanna Di Trapani and Kathryn F. Tonissen. The Interaction between Redox and Hypoxic Signalling Pathways in the Dynamic Oxygen Environment of Cancer Cells (2013), Carcinogenesis, Edited by Tonissen Kathryn, Chapter 7, 125-152. Therese C. Karlenius, Fenil Shah, Giovanna Di Trapani, Frank M. Clarke and Kathryn F. Tonissen. Cycling Hypoxia up-regulates Thioredoxin levels in human MDA-MB-231 breast cancer cells. Biochemical and Biophysical Research Communications, (2012), 419, 350-355. Giovanna Di Trapani and Frank Clarke “Biotechniques Laboratory: An enabling course in the biological sciences”, Biochemistry and Molecular Biology Education (BAMBED), 2012, 40 (1), 29-36. Sarah-Jane Gregory and Giovanna Di Trapani “A Blended Learning Approach to Laboratory Preparation”, International Journal of Innovation in Science and Mathematics Education, (2012), 20(1), 51-64. Susan Lee, Giovanna Di Trapani and J. Alejandro Lopez. “Using student presentations of clinical case studies to integrate knowledge, revise concepts and develop graduate attributes”. Proceedings of the 4th International Conference of Education, Research, Innovation. Madrid 14-17 November, 2011. Kathryn F. Tonissen and Giovanna Di Trapani. Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy, Molecular Nutrition and Food Research, (2009), 53, 87-103