van Oijen, Antoine - University of Wollongong

个人简介

Professional Experience 2001-2004 Postdoctoral Fellow, Harvard University, USA 2004-2010 Assistant Professor, Harvard Medical School, USA 2010-2014 Professor, Groningen University, the Netherlands 2015-present Professor, School of Chemistry, University of Wollongong Other Experience and Professional Memberships 2007-2010 Scientific Advisory Board Ion Torrent Systems 2011-present Editorial Board member Cell Reports 2012-present Council member (elected) Biophysical Society 2013-present Editorial Board member Biophysical Journal 2013-present Scientific Advisory Board 4Catalyzer

研究领域

The fundamental processes of life, one molecule at a time: Single-molecule biophysics

近期论文

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A.M. van Oijen, M. Ketelaars, J. Köhler, T.J. Aartsma, J. Schmidt; Unraveling the electronic structure of individual photosynthetic pigment-protein complexes; Science 1999; 285: 400-402 A.M. van Oijen, P.C. Blainey, D.J. Crampton, C.C. Richardson, T. Ellenberger, X.S. Xie; Single-molecule kinetics reveal base dependence and dynamic disorder of ambda exonuclease; Science 2003; 301: 1235-1238 B.P. English, W. Min, A.M. van Oijen, K.T. Lee, G. Luo, H. Sun, B.J. Cherayil, S.C. Kou, X.S. Xie; Ever-Fluctuating Single Enzyme Molecules: the Michaelis-Menten Equation Revisited; Nature Chemical Biology, 2006; 2: 87-94 J.B. Lee, R.K. Hite, S.M. Hamdan, X.S. Xie, C.C. Richardson, A.M. van Oijen; DNA primase acts as a molecular brake in DNA replication; Nature, 2006; 439: 621-624 S.M. Hamdan, D.E. Johnson, N.A. Tanner, J.-B. Lee, U. Qimron, S. Tabor, A.M. van Oijen, C.C. Richardson; Dynamic DNA Helicase-DNA Polymerase Interactions Assure Processive Replication Fork Movement; Molecular Cell, 2007; 27: 539-549 N.A. Tanner, S.M. Hamdan, J. Slobodan, K.V. Loscha, P.M. Schaeffer, N.E. Dixon, A.M. van Oijen; Single-molecule studies of fork dynamics in Escherichia coli DNA replication; Nature Structure & Molecular Biology, 2008; 15: 170-175 D.L. Floyd, J. Ragains, J.J. Skehel, S.C. Harrison, A.M. van Oijen; Single-particle kinetics of influenza membrane fusion; Proc. Natl. Acad. Sci. USA, 2008; 105: 15382-15387 S.M. Hamdan, J.J. Loparo, M. Takahashi, C.C. Richardson, A.M. van Oijen; Dynamics of individual DNA replication loops reveal temporal control of lagging-strand synthesis; Nature, 2009; 457: 336-339 H. Yardimci, A.B. Loveland, S. Habuchi, A.M. van Oijen, J.C. Walter; Uncoupling of sister replisomes during eukaryotic DNA replication Mol. Cell, 2010; 40: 834-840 A. Tafvizi, F. Huang, A.R. Fersht, L.A. Mirny, A.M. van Oijen; A single-molecule characterization of p53 search on DNA; Proc. Natl. Acad. Sci. USA, 2011; 108: 563-568 J.J. Loparo, A.W. Kulczyk, C.C. Richardson, A.M. van Oijen; Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange; Proc. Natl. Acad. Sci. USA, 2011; 108, 3584-3589 H. Yardimci, X. Wang, A.B. Loveland, I. Tappin, D.Z. Rudner, J. Hurwitz J, A.M. van Oijen, J.C. Walter; Bypass of a protein barrier by a replicative DNA helicase; Nature, 2012; 492, 205-209 A.B. Loveland, S. Habuchi, J.C. Walter, A.M. van Oijen; A general approach to break the concentration barrier in single-molecule imaging; Nature Methods, 2012; 9, 987-992