Wilson, Mark - University of Wollongong - School of Biological Sciences

个人简介

Academic Degrees PhD The University of Sydney 1985 BSc (Hons) (First class) The University of Sydney 1980 Prizes, Scholarships, Fellowships and Awards VC's Award for Supervisor of the Year, University of Wollongong 2008 Outstanding Achievement in Teaching Award, Australian College of Education 1997 VC's Excellence in Teaching Award, University of Wollongong 1997 Travelling Fellowship The Faculty of Medicine, University of Sydney 1993 Medical Research Fellowship, The Medical Foundation 1993

研究领域

Extracellular chaperones Extracellular protein homeostasis (proteostasis) Motor Neurone Disease (MND) Cellular analyses (e.g. flow cytometry, confocal microscopy)

近期论文

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Yerbury, J., Stewart, E., Wyatt, A. and Wilson, M R. (2005) Quality control of protein folding in extracellular space. EMBO Reports 6: 1131-1136 Yerbury, JJ, Kumita, JR, Meehan, S, Dobson, CM & Wilson, MR. (2009) Alpha-2-macroglobulin and haptoglobin suppress amyloid formation by interacting with prefibrillar protein species. Journal of Biological Chemistry 284: 4246-4254 Wyatt, AR and Wilson, MR (2010) Identification of human plasma proteins as major clients for the extracellular chaperone clusterin. Journal of Biological Chemistry 285: 3532-3539 Wyatt, AR, Yerbury, JJ, Berghoffer, P, Greguric, I, Katsifis, A, Dobson, CM and Wilson, MR (2011) Clusterin facilitates in vivo clearance of extracellular misfolded proteins. Cell and Molecular Life Sciences 68: 3919-3931 Narayan, P, Orte, A, Clarke, RW, Bolognesi, B, Hook, S, Ganzinger, K, Meehan, S, Wilson, MR1, Dobson, C1 and Klenerman, D1 (2012) The extracellular chaperone clusterin sequesters oligomeric forms of the Alzheimer’s Ab peptide. Nature Structural & Molecular Biology 19: 79-84 1 Corresponding authors Wyatt, AR, Yerbury, JJ, Ecroyd, H & Wilson, MR (2012) Extracellular chaperones and proteostasis. Annual Review of Biochemistry in press (accepted 20 Sept 2012)