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个人简介

刘基巍 职务: 教授 专业: 肿瘤学 Education/Professional Experience Sep.1980-Jul.1986 Norman Bethune Medical University English class of Clinical medine, bachelordegree Sep.1986-Jul.1989 Norman Bethune Medical University Oncology, Masterdegree Sep.2001-Jul.2004 Dalian Medical University Molecular biology, Ph.D. Sep.1989.7up to now The First Affiliated Hospital of Dalian Medical University Department of Oncology,Professor andDepartment Director Jun.1998-Dec.1998 Japan KitakyushuMedical Center Cancer center, Visiting scholar Oct.2006-Mar.2007 Northwestern University, USA Robert Lurrie cancer center, Visiting scholar Research Projects/Grants Principal Investigator of the National Natural Science Foundation of China-“Study on the mechanism of Rg3 on the effect of novel serum marker d-GM3 in the malignant melanoma metastasis” Admission Plan/Requirements One for Doctoral Candidate One for Master’s Degree Candidate

近期论文

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1. Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation. PLOS ONE, 2014, 9 (12): e115401. IF:3.534, Corresponding author doi: 10.1371/journal.pone.0115401. 2. Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cells proliferation via decreasing of FUT4/LeY expression. Int J Oncol. 2015, 46 (4): 1667-76. IF:3.025, Corresponding author; doi: 10.3892/ijo.2015.2886. 3. Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death. Int J Oncol. 2015, 47: 701-709. IF: 3.025, Corresponding author; doi: 10.3892/ijo.2015.3057. 4. Clinical observation of liver cancer patients treated with axitinib and cabozantinib after failed sorafenib treatment: a case report and literature review.Cancer Biol Ther. 2015; 16 (2): 215-8. IF: 3.072, Corresponding author; doi: 10.4161/15384047.2014.962318. 5. Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4. Oncotarget ,2016, 7(2):1619-1632.IF:6.359 ,Corresponding author;DOI:10.18632/oncotarget.6451 6. Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions. Toxicol In Vitro, 2016 ,31:158-166. IF:2.903, Co-corresponding author;DOI:10.1016/j.tiv.2015.09.025 7. Effects of cinobufacini injection on cell proliferation and the expression of topoisomerases in human HepG-2 hepatocellular carcinoma cells, 2015, MOLECULAR MEDICINE REPORTS, Volume: 12; Issue: 1; Pages: 1598-1604; Impact Factor(JCR2014) IF: 1.554, Co-corresponding author; DOI:10.3892/mmr.2015.3552

学术兼职

Standing Committee member of the Chinese society of Clinical Oncology (CSCO) Committeemember of Chemotherapy, Chinese Anti-cancer Association Vice Chairman of Small cell lung cancer expert committee-CSCO Vice Chairman of Cancer Society of Liaoning Province, Chinese Medical Association Vice Chairman of ChemotherapyCommittee,Liaoning Anti-cancer Association Committeemember of Oncologist, Chinese Medical Doctor Association

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