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个人简介

黄琳 职务: Professor 专业: 病理学 Education/Working Experience EDUCATION 2002-2006 Ph.D., in Molecular Oncology and Microbiology, Graduate School of Medicine and Dentistry, Tokyo Medical and Dental University, Tokyo, Japan. 1998-2001 Master of Medicine in Pathology and Pathophysiology, Graduate School, Dalian Medical University, Dalian, China. 1993-1998 M.D., in Clinical Medicine, Dalian Medical University, Dalian, China. EMPLOYMENT 2012.10 -present Professor, Dalian Medical University, Dalian, China. 2012.4-2013.3 Assistant Professor, University of Tsukuba, Ibaraki, Japan. 2008.4 -2012.3 Foreign Postdoctoral Researcher, RIKEN, Saitama, Japan. 2006.4 – 2007.3 Postdoctoral Fellow, Research Institute, National Cancer Center, Tokyo, Japan. Research Projects/Grants 1. Liaoning Natural Science Fundation Program, 2014-2017. 2. Liaoning Provincial Climbing Scholars Supporting Program, 2014-2017. 3. Liaoning Provincial Developing Program for Distinguished Young Scholars of University (LJQ2013096), 2013-2016. 4. National Natural Science Fundation of China Program (81201562), 2013-2015. 5. RIKEN Foreign Postdoctoral Researchers Program (080081), 2008-2012. Admission Plan/Requirements 1 for master student

近期论文

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1. Dan Lv, Jinye Liu, Lianying Guo, Dawei Wu, Ken Matsumoto, Lin Huang. PRAS40 deregulates apoptosis in Ewing sarcoma family tumors by enhancing the insulin receptor/Akt and mTOR signaling pathways. Am J Cancer Res. In press. 2. Huang L, Haratake K, Miyahara H, Chiba T. Proteasome activators, PA28 and PA200, play indispensable roles in male fertility. Sci Rep. 6:23171, 2016. 3. Huang L, Kuwahara I, Matsumoto K. EWS represses cofilin 1 expression by inducing nuclear retention of cofilin 1 mRNA. Oncogene. 33, 2995-3003, 2014. 4. Huang L, Nakai Y, Kuwahara I, Matsumoto K. PRAS40 is a functionally critical target for EWS repression in Ewing's sarcoma. Cancer Res. 72, 1260-9, 2012. 5. Huang L, Shitashige M, Satow R, Honda K, Ono M, Yun J, Tomida A, Tsuruo T, Hirohashi S, Yamada T. Functional interaction of DNA topoisomerase IIa with the b-catenin and T-cell factor-4 complex. Gastroenterology. 133, 1569-78, 2007. 6. Huang L, Watanabe M, Chikamori M, Kido Y, Yamamoto T, Shibuya M, Gotoh N, Tsuchida N. Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways. Oncogene. 25, 6457-66, 2006. 7. Huang L, Gotoh N, Zhang S, Shibuya M, Yamamoto T, Tsuchida N. SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation. Biochem Biophys Res Commun. 324, 1011-17, 2004.

学术兼职

Member of Chinese Association of Pathophysiology Young Committee Member of Immunology Section of Chinese Association of Pathophysiology Young Committee Member of Cancer Section of Chinese Association of Pathophysiology

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