研究领域

Pharmacology

Opioid and cannabinoid receptor signalling Effects of natural variants of opioid receptors on drug action Molecular targets of cannabis constituents Illicit synthetic cannabinoids Opioid receptors in cancer

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Redmond W, Cawston E, Grimsey N, Stuart J, Edington A, Glass M, Connor M (2015). Identification of N-arachidonoyl dopamine as a highly biased ligand at cannabinoid CB1 receptors. Brit J Pharmacol, In Press Cawston E, Connor M, Di Marzo V, Silvestri R, Glass M (2015). Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signalling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors. J Med Chem, 58, 5979-5988 Banister S, Moir M, Stuart J, Kevin R, Wood K, Longworth M, Wilkinson S, Beinat C, Buchanan A, Glass M, Connor M, McGregor I, Kassiou M (2015). The pharmacology of indole and indazole synthetic cannabinoid designer drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA and 5F-ADBICA. ACS Chem Neurosci 6, 1546-1559 Knapman AJ, Santiago M, Connor M (2015). The A6V polymorphism of the human µ-opioid receptor negatively impacts signalling of morphine and endogenous opioids in vitro. Brit of Pharmacol, 172, 2258-2272