研究领域

Ecology

The evolution of defence: Investigates the internal defence (immune) mechanisms of advanced invertebrates (ascidians/tunicates) at the cell and molecular biological levels. The overall goals of this work are: (i) to determine the ways in which invertebrate animals defend themselves from infection, and, (ii) to study the ways in which immune mechanisms have evolved throughout the animal kingdom. Effects of environmental pollutants on marine invertebrates Studies the effects of environmental pollutants on the cell and molecular biological systems of common marine invertebrates ascidians/tunicates). The aims of this research are: (i) to identify the cellular systems that are affected by specific pollutants, and determine the ramifications of those cellular effects on the whole animal, and, (ii) to develop rapid and reproducible cell or molecular biological assays for the biomonitoring of pollution.

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D. Butt, S. J. O'Connor, R. Kuchel, W. A. O'Connor, and D. A. Raftos. Effects of the muscle relaxant, magnesium chloride, on the sydney rock oyster (saccostrea glomerata). Aquaculture, 275(1-4):342-346, 2008. S. Aladaileh, S. V. Nair, and D. A. Raftos. Effects of noradrenaline on immunological activity in sydney rock oysters. Developmental and Comparative Immunology, 32(6):627-636, 2008. V. Brockton, J. H. Henson, D. A. Raftos, A. J. Majeske, Y. O. Kim, and L. C. Smith. Localization and diversity of 185/333 proteins from the purple sea urchin - unexpected protein-size range and protein expression in a new coelomocyte type. Journal of Cell Science, 121(3):339-348, 2008. D. Butt and D. Raftos. Phenoloxidase-associated cellular defence in the sydney rock oyster, saccostrea glomerata, provides resistance against qx disease infections. Developmental and Comparative Immunology, 32(3):299-306, 2008. S. Aladaileh, S. V. Nair, and D. A. Raftos. Induction of phenoloxidase and other immunological activities in sydney rock oysters challenged with microbial pathogen-associate molecular patterns. Fish & Shellfish Immunology, 23(6):1196-1208, 2007.