Karuso, Peter - Macquarie University - Department of Chemistry and Biomolecular Sciences

研究领域

Chemical Biology and Natural Product Chemistry, in particular Marine Natural Products and chemical proteomics. Phage display/yeast surface display in the isolation of small molecule bining proteins (Reverse Chemical Proteomics). Structure and dynamics of biomolecules using high-field NMR spectroscopy.

近期论文

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Peixoto, P. A., Boulange, A., Ball, M., Naudin, B., Alle, T., Cosette, P., Karuso, P. Franck, X. (2014) "Design and Synthesis of Epicocconone Analogues with Improved Fluorescence Properties" J. Am. Chem. Soc., 136, 15248-56 Shengule, S. R., Karuso, Peter "Diastereoselective Pictet-Spengler reactions of a tethered 2-aminoimidazole" (2014) Aust. J. Chem., 67, 184-91. Chatterjee, S., Karuso, P., Boulange, A., Peixoto, P. A., Franck, X., Datta, A. "The Role of Different Structural Motifs in the Ultrafast Dynamics of Second Generation Protein Stains" J. Phys. Chem. B (2013), 117, 14951-9. Shengule, S. R., Karuso, Peter "Three-component Mannich-like reaction of 2-aminoimidazole" Aust. J. Chem. (2011), 64, 1617-20. Shengule, S. R., Loa-Kum-Cheung, W. L., Parish, C. R., Blairvacq, M., Meijer, L., Nakao, Y., Karuso, Peter "A One-Pot Synthesis and Biological Activity of Ageladine A and Analogues" J. Med. Chem. (2011), 54, 2492-503. Bickmeyer, U., Heine, M., Podbielski, I., Muend, D., Köck, M., Karuso, Peter "Tracking of fast moving neuronal vesicles with ageladine A" Biochem. Biophys. Res. Commun. (2010), 402, 489-94. Piggott, A. M., Kriegel, A. M., Willows, R. D., Karuso, Peter "Rapid isolation of novel FK506 binding proteins from multiple organisms using gDNA and cDNA T7 phage display" Bioorg. Med. Chem. (2009), 17, 6841-50. Piggott, A. M. and Karuso, P. (2008) "Rapid identification of a protein binding partner for the marine natural product kahalalide F using reverse chemical proteomics" ChemBioChem, 9, 524-30. Karuso, P., Crawford, A. S., Veal, D. A., Scott, G. B. I. and Choi, Y-H. (2008) "Real-time fluorescence monitoring of proteolysis" J. Proteome Res., 7, 361-6. Ball, M. S. and Karuso, Peter "Mass Spectral Compatibility of Four Proteomics Stains" J. Proteome Res. (2007), 6, 4313-20