Jamie, Joanne - Macquarie University - Department of Chemistry and Biomolecular Sciences

研究领域

Working in partnership with Indigenous people on traditional medicinal plant knowledge for cultural preservation and drug discovery. Understanding the structure, function and inhibition of the medicinally important human enzyme indoleamine 2,3-dioxygenase to rationally develop potent inhibitors. Understanding age-related nuclear cataract and human lens chemistry using synthesis and biological models.

近期论文

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J Gaikwad, V Khanna, S Vemulpad, J Jamie, J Kohen, S Ranganathan, "CMKb: a Web Based Prototype for Integrating Australian Aboriginal Customary Medicinal Plant Knowledge". BMC Bioinformatics, 2008, 9, S25-33. " S Vemulpad, J Jamie, "Partnerships in Traditional Medicinal Plant Research". Issues, 2008, 84, 45-48.. J Mizdrak, P Hains, R Truscott, J Jamie, M Davies, "Tryptophan-Derived Ultraviolet Filter Compounds Covalently Bound to Lens Proteins are Photosensitisers of Oxidative Damage", Free Radical Biology & Medicine, 2008, 44, 1108-1119. C Austin, F Astelbauer, P Kosim-Satyaputra, H Ball, R Willows, J Jamie, N Hunt, "Mouse and Human Indoleamine 2,3-Dioxygenase Display Some Direct Biochemical and Structural Properties", Amino Acids, 2008, 99-106. J Mizdrak, PG Hains, RJW Truscott, MJ Davies, JF Jamie, "Novel Human Lens Metabolite from Normal Cataractous Human Lenses", Tetrahedron, 2007, 63, 4990-4999." Q Liu, D Harrington, JL Kohen, S Vemulpad, JF Jamie, "Bactericidal and Cyclooxygenase Inhibitory Diterpenes from Eremophila sturtii", Phytochemistry, 2006, 67, 1256-1261." A Matin, IM Streete, IM Jamie, RJW Truscott, JF Jamie, "A Fluorescence-Based Assay for Indoleamine 2,3-Dioxygenase", Analytical Biochemistry, 2006, 349, 96-102. N Brouwer, J Kohen, J., J Jamie, S Vemulpad, "Modification of the Fluorescein Diacetate Assay for Screening of Antifungal Agents Against Candida albicans: Comparison with the NCCLS methods", Journal of Microbiological Methods, 2006, 66, 234-241. S Wanandy, N Brouwer, Q Liu, A Mahon, S Cork, P Karuso, S Vemulpad, J Jamie, "Optimisation of the Fluorescein Diacetate Antibacterial Assay", Journal of Microbiological Methods, 2005, 60, 21-30. N Brouwer, Q Liu, D Harrington, J Kohen, S Vemulpad, J Jamie, M Randall, D Randall, "An Ethnopharmacological Study of Medicinal Plants in New South Wales", Molecules, 2005, 10, 1252-1262.