Palmer, Amy - University of Colorado - Chemistry and Biochemistry

个人简介

Ph.D.: Biophysical Chemistry, Stanford University, 2001 Postdoctoral Fellow: NIH Postdoctoral Fellow University of California San Diego 2001 - 2005

研究领域

Cell Signaling Chemical Biology/Genetics Molecular Biophysics Bioinorganic Chemistry Biophysics

近期论文

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Dean, K. M., Lubbeck, J. L., Davis, L. M., Regmi, C. K., Chapagain, P. P., Gerstman, B. S., et al. Microfluidics-based selection of red-fluorescent proteins with decreased rates of photobleaching. Integrative Biology : Quantitative Biosciences From Nano to Macro. 2014. Farnsworth, N. L., Mead, B. E., Antunez, L. R., Palmer, A. E., & Bryant, S. J. Ionic osmolytes and intracellular calcium regulate tissue production in chondrocytes cultured in a 3D charged hydrogel. Matrix Biology : Journal of the International Society for Matrix Biology. 2014. Dean, K. M., & Palmer, A. E. Advances in Fluorescence Labeling Strategies for Dynamic Cellular Imaging. Nature Chemical Biology, 10(7), 512–523. 2014. Carter, K. P., Young, A. M., & Palmer, A. E. Fluorescent Sensors for Measuring Metal Ions in Living Systems. Chemical Reviews, 114 (8), 4564–4601. 2014. Park, J.G. & Palmer A.E. Quantitative Measurement of Ca2+ and Zn2+ in Mammalian Cells Using Genetically Encoded Fluorescent Biosensors. Methods in Molecular Biology 1071, 29-47. 2013. Stavru, F., Palmer, A. E., Wang, C., Youle, R. J., & Cossart, P. Atypical mitochondrial fission upon bacterial infection. Proc Natl Acad Sci USA, 110(40), 16003–16008. 2013. Qin, Y., Miranda, J. G., Stoddard, C. I., Dean, K. M., Galati, D. F., & Palmer, A. E. Direct Comparison of a Genetically Encoded Sensor and Small Molecule Indicator: Implications for Quantification of Cytosolic Zn2+. ACS Chemical Biology, 8, 2366?2371. 2013. Davis, L. M., Lubbeck, J. L., Dean, K. M., Palmer, A. E., & Jimenez, R. Microfluidic cell sorter for use in developing red fluorescent proteins with improved photostability. Lab on a Chip, 13(12), 2320. 2013. Jeong J, Walker JM, Wang F, Park JG, Palmer AE, Guita C, Rohrbach M, Steinmann B, Eide DJ. Promotion of vesicular zinc efflux by Zip13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome. Proc Natl Acad Sci USA. epub ahead of print 2012. Miranda, J. G., Weaver, A. L., Qin, Y., Park, J. G., Stoddard, C. I., Lin, M. Z., & Palmer, A. E. New Alternately Colored FRET Sensors for Simultaneous Monitoring of Zn2+ in Multiple Cellular Locations. PLoS ONE, 7(11), 2012. Geng X, Huang C, Qin Y, McCombs JE, Yuan Q, Harry BL, Palmer AE, Xia NS, and Xue D. Hepatitits B virus X protein targerts Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction. Proc Natl Acad Sci USA 2012. Park, J.G., Qin, Y. Galati, D.F., Palmer, A.E., New Sensors for Quantitative Measurement of Mitochondrial Zinc (II). ACS Chem. Biol. 2012. Epub. Dean, K.M., Qin, Y., Palmer, A.E. Visualizing Metal Ions in Cells: An Overview of Analytical Techniques, Approaches, and Probes. Biochim. Biophys. Acta. 2012. Sep;1823(9)1406-15. Differential Effects of Procaspase-3 Activating Compounds in the Induction of Cancer Cell Death. West, D.C., et al. Mol. Pharm. 2012. May 7;9(5);1425-34. Lubbeck, J.L., Dean, K.M., Ma, H., Palmer, A.E., Jimenez, R. Microfluidic Flow Cytometer for Quantifying Photobleaching of Fluorescent Proteins in Cells. Anal. Chem. 2012. May 7;9(5):1425-34. Ma, H., Gibson, E.A., Dittmer, P.J., Jimenez, R. Palmer, A.E. High-Throughput Examination of FRET-detected Metal Ion Response in Mammalian Cells. J. Am. Chem. Soc. 2012. Feb 8;134(5):2488-91. Dean K.M., Lubbeck J.L., Binder J.K., Schwall L.R., Jimenez R, Palmer A.E. Analysis of Red-Fluorescent Proteins Provides Insight into Dark-State Conversion and Photodegradation. Biophys J. 2011 Aug 17;101(4):961-9. Qin, Y., Dittmer, P.J., Park, J.G., Jansen, K.B., Palmer, A.E. Measuring Steady State and Dynamic ER and Golgi Zn2+ with Genetically Encoded Sensors. Proc. Nat. Acad. Sci. U S A, 108(18):7351-6. Palmer AE, Qin Y, Park JG, McCombs JE. Trends Biotechnol. 2011 Mar; 29(3):144-52 Perocchi, F., Gohil, V.M., Girgis, H.S., Bao, X.R., McCombs, J.E., Palmer, A.E., Mootha, V.K. MICU1 encodes a mitochondrial EF hand protein required for Ca(II) uptake. Nature. 2010. Sep 16;467(7313):291-6