研究领域
有机合成方法学;不对称催化;自由基化学;偶联反应; 光催化绿色反应;药物及其中间体的合成和工艺研究
专利
(5)朱映光,曹淑君,郭康,彭琛,石云,一种菲啶类杂环化合物的制备方法。专利申请号: 201710872338.X;公开号:CN108299296A
(4) 朱映光,周华婷,彭琛,孟菲,顾晨,一种四取代烯烃及其制备方法。专利申请号: 201711308278.5;公开号:CN108218707A
(3) 胡文浩, 朱映光, 翟昌伟, 岳永力, 杨琍苹, “一种二氢吡咯衍生物的制备方法”, 专利号: ZL200810203772.X
(2) 胡文浩, 阚洪柱, 朱映光, 任白燕, 马海坤, 杨琍苹, “一种合成(R)-3-哌啶乙酸乙酯盐酸 盐的方法”, 专利号: ZL200910198818.8
(1) 胡文浩, 戚浩强, 朱映光, 杨琍苹, “一种 3-氮杂-4-氧代-三环[4.2.1.0 (2,5)]壬-7-烯的合成 方法”, 专利号: ZL200910048909.3
科研项目
(6)主持国家自然科学基金(21502096)
(5) 主持江苏省自然科学基金(BK20150652)
(4) 主持中央高校基本科研业务费专项资金项目(KJQN201629)
(3) 主持南京农业大学引进人才科研启动经费
(2) 作为主要成员曾参与美国 NIH 资助的基金项目(NIH-5R01-GM083944)
(1) 作为主要成员曾参与国家自然科学基金面上项目(20772033,20872036)和国家杰出青年 科学基金(21125209)等研究工作
近期论文
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(25) Fei Meng#, Honglin Zhang#, Han He, Ning Xu, Qin Fang, Kang Guo, Shujun Cao, Yun Shi, Yingguang Zhu*, “Copper-catalyzed domino cyclization/thiocyanation of unactivated olefins: access to SCN-containing pyrazolines”, Adv. Synth. Catal. 2020, 362, 248-254. (SCI, IF = 5.451) (24) Fei Meng, Qin Fang, Weidong Yuan, Ning Xu, Shujun Cao, Jianlin Chun, Jie Li, Honglin Zhang*, Yingguang Zhu*, “Access to cyano-substituted pyrazolines through copper-catalyzed cascade cyanation/cyclization of unactivated olefins”, Org. Chem. Front. 2020, 7, 1358-1364. (SCI, IF = 5.076) (23) Fei Meng, Honglin Zhang, Jie Li, Jianlin Chun, Yun Shi, Han He, Bin Chen, Zhenbo Gao, Yingguang Zhu*, “Highly selective and switchable access to tetrasubstituted alkenyl sulfones and naphthyl sulfones: 1,4-aryl migration versus cyclization”, Org. Lett. 2019, 21, 8537-8542. (SCI, IF = 6.555) (22) Kang Guo, Honglin Zhang, Shujun Cao, Chen Gu, Huating Zhou, Jie Li, Yingguang Zhu*, “Copper-Catalyzed Domino Cyclization/Trifluoromethylthiolation of Unactivated Alkenes: Access to SCF3-Containing Pyrrolines”, Org. Lett. 2018, 20, 2261−2264. (SCI, IF = 6.555) (21) Zhen Chen, Kang Guo, Rongshun Chen, Chen Gu, Huating Zhou, Yingguang Zhu*, “Facile Access to β-Ketosulfones via Mn-Mediated Reductive Coupling of α-Bromoketones with Sulfonyl Chlorides”, Chin. J. Org. Chem. 2018, 38, 963−968. (SCI) (20) Yun Shi#, Rongshun Chen#, Kang Guo, Fei Meng, Shujun Cao, Chen Gu, Yingguang Zhu*, “Visible light-promoted metal-free aerobic oxyphosphorylation of olefins: A facile approach to β-ketophosphine oxides”, Tetrahedron Lett. 2018, 59, 2062–2065. (SCI, IF = 2.125) (19) Fei Meng, Honglin Zhang, Kang Guo, Jiayue Dong, Ai-Min Lu, Yingguang Zhu*, “Access to Cyano-Containing Isoxazolines via Copper-Catalyzed Domino Cyclization/Cyanation of Alkenyl Oximes”, J. Org. Chem. 2017, 82, 10742−10747. (SCI, IF = 4.805) (18) Yingguang Zhu, Qian Wang, Richard G. Cornwall, Yian Shi*, “Organocatalytic Asymmetric Epoxidation and Aziridination of Olefins and Their Synthetic Applications”, Chem. Rev. 2014, 114, 8199–8256. (SCI, IF = 52.613) (17) Yingguang Zhu, Richard G. Cornwall, Haifeng Du, Baoguo Zhao, Yian Shi*, “Catalytic
Diamination of Olefins via N–N Bond Activation”, Acc. Chem. Res. 2014, 47, 3665–3678. (SCI, IF = 24.348) (16) Yingguang Zhu, Changwei Zhai, Liping Yang, Wenhao Hu*, “Copper(II)-catalyzed highly diastereoselective three-component reactions of aryl diazoacetates with alcohols and chalcones: an easy access to furan derivatives”, Chem. Commun. 2010, 46, 2865-2867. (SCI, IF = 6.718) (本文被 Synfacts 收录‚ Synfacts 2010, 691) (15) Yingguang Zhu,# Tao Xiong,# Wenyong Han,# Yian Shi*, “Copper-Catalyzed Oxidative Homo- and Cross-Coupling of Grignard Reagents Using Diaziridinone”, Org. Lett. 2014, 16, 6144–6147. (SCI, IF = 6.555) (14) Yingguang Zhu, Yian Shi*, “Cu(I)-Catalyzed Sequential Diamination and Dehydrogenation of Terminal Olefins: A Facile Approach to Imidazolinones”, Chem. Eur. J. 2014, 20, 13901–13904. (SCI, IF = 5.696) (13) Yingguang Zhu, Changwei Zhai, Yongli Yue, Liping Yang, Wenhao Hu*, “One-pot three-component tandem reaction of diazo compounds with anilines and unsaturated ketoesters: a novel synthesis of 2,3-dihydropyrrole derivatives”, Chem. Commun. 2009, 1362–1364. (SCI, IF = 6.718) (12) Yingguang Zhu, Baoguo Zhao, Yian Shi*, “Highly Efficient Cu(I)-Catalyzed Oxidation of Alcohols to Ketones and Aldehydes with Diaziridinone”, Org. Lett. 2013, 15, 992–995. (SCI, IF = 6.555) (本文被 Synform 收录‚ Synform 2013, A85–A86) (11) Yingguang Zhu, Yian Shi*, “Facile Cu(I)-Catalyzed Oxidative Coupling of Anilines to Azo Compounds and Hydrazines with Diaziridinone under Mild Conditions”, Org. Lett. 2013, 15, 1942–1945. (SCI, IF = 6.555) (10) Yingguang Zhu, Yian Shi*, “A facile copper(I)-catalyzed homocoupling of terminal alkynes to 1,3-diynes with diaziridinone under mild conditions”, Org. Biomol. Chem. 2013, 11, 7451–7454. (SCI, IF = 6.492) (9) Yingguang Zhu, Changwei Zhai, Liping Yang, Wenhao Hu*, “Highly Regioselective, Three-Component Reactions of Diazoacetates with Anilines and β,γ-Unsaturated α-Keto Esters: 1,2-Addition versus 1,4-Addition”, Eur. J. Org. Chem. 2011, 1113–1124. (SCI, IF = 3.154) (8) Yingguang Zhu, Hongzhu Kan, Liqin Jiang, Wenhao Hu*, “Practical and Scalable Synthesis of Ethyl (R)-Piperidine-3-acetate”, Synth. Commun. 2012, 42, 1137-1145. (SCI, IF = 0.984) (7) Yingguang Zhu, Changwei Zhai, Wenhao Hu*, “Asymmetric Multicomponent Reactions”, Progress in Chemistry 2010, 22, 1380–1396. (SCI, IF = 0.714) (6) Huaiji Zheng, Yingguang Zhu, Yian Shi*, “Palladium(0)-Catalyzed Heck Reaction/C-H Activation/Amination Sequence with Diaziridinone: A Facile Approach to Indolines” , Angew. Chem. Int. Ed. 2014, 53, 11280–11284. (SCI, IF = 11.336) (5) Xingao Peng, Yingguang Zhu, Thomas A. Ramirez, Baoguo Zhao, Yian Shi*, “New Reactivity of Oxaziridine: Pd(II)-Catalyzed Aromatic C-H Ethoxycarbonylation via C-C Bond Cleavage”, Org. Lett. 2011, 13, 5244-5247. (SCI, IF = 6.555) (4) Thomas A. Ramirez, Qian Wang, Yingguang Zhu, Huaiji Zheng, Xingao Peng, Richard G. Cornwall, Yian Shi*, “Pd(0)-Catalyzed Sequential C-N Bond Formation via Allylic and Aromatic C-H Amination of α-Methylstyrenes with Diaziridinone”, Org. Lett. 2013, 15, 4210-4213. (SCI, IF = 6.492)
(3) Jingjing Ji, Xia Zhang, Yingguang Zhu, Yu Qian, Jing Zhou, Liping Yang, Wenhao Hu*, “Diastereoselectivity Switch in Cooperatively Catalyzed Three-Component Reactions of an Aryldiazoacetate, an Alcohol, and a β,γ-Unsaturated α-Keto Ester”, J. Org. Chem. 2011, 76, 5821-5824. (SCI, IF =4.805) (2) Xia Zhang, Jingjing Ji, Yingguang Zhu, Changcheng Jing, Ming Li, Wenhao Hu*, “A highly diastereoselective three-component tandem 1,4-conjugated addition–cyclization reaction to multisubstituted pyrrolidines”, Org. Biomol. Chem. 2012, 10, 2133–2138. (SCI, IF = 3.487) (1) Baoguo Zhao, Xingao Peng, Yingguang Zhu, Thomas A. Ramirez, Richard G. Cornwall, Yian Shi*, “Cu(I)-Catalyzed Diamination of Conjugated Dienes. Complementary Regioselectivity from Two Distinct Mechanistic Pathways Involving Cu(II) and Cu(III) Species”, J. Am. Chem. Soc. 2011, 133, 20890-20900. (SCI, IF = 14.357)
书籍章节 丁奎岭,范青华,刘元红,胡文浩,杨震,王正,李贵杰,朱映光,有机合成化学(第一章), pp 32-108;杜灿屏,麻生明主编,《有机化学学科前沿与展望》,科学出版社,2011 年。