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个人简介

刘芳,教授,博士生导师。2014年取得博士学位,师从计算有机化学界知名学者、美国 科学院院士 K. N. Houk教授;先后在美国加州大学洛杉矶分校和南京大学进行博士后研 究,2018年作为高层次引进人才加入南京农业大学理学院。主要研究有机反应机理、活 性和选择性以及催化剂设计。在 Nature, Acc. Chem. Res., J. Am. Chem. Soc., Angew. Chem. Int. Ed.等国际期刊上发表 SCI论文 20余篇,其中第一作者文章 7篇。 工作经历 2018/09-今:南京农业大学,理学院,教授,博士生导师 2016/10-2018/08:南京大学,化学化工学院,博士后 2016/03-2016/09:美国加州大学洛杉矶分校(UCLA),化学与生物化学学院,博士后 教育经历 2009/09-2014/06:美国加州大学洛杉矶分校(UCLA),化学与生物化学学院,博士 2005/09-2009/06:南开大学,化学学院,学士 教学信息 有机化学,物理化学,计算化学课程

研究领域

有机反应机理,催化剂设计

科研项目 (2)南京农业大学引进人才科研启动经费,2018/09-2023/09,在研,主持 (1)中国博士后科学基金面上项目,2017/08-2018/08,结题,主持

近期论文

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21. Yi-Shuang Wang, Bo Zhang, Jiapeng Zhu, Cheng-Long Yang, Yu Guo, Cheng-Li Liu, Fang Liu, Huiqin Huang, Suwen Zhao, Yong Liang, Rui-Hua Jiao, Ren-Xiang Tan, and Hui-Ming Ge: “Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis,” J. Am. Chem. Soc. 2018, 140, 10909-10914. 20. Joyann Barber, Michael Yamano, Melissa Ramirez, Evan Darzi, Rachel Knapp, Fang Liu, K. N. Houk, and Neil Garg: “Diels–Alder Cycloadditions of Strained Azacyclic Allenes,” Nat. Chem. 2018, 10, 953-960. 19. Huimin Tao‡, Fang Liu‡, Ruxin Zeng, Zhuzhou Shao, Lufeng Zou, Yang Cao, Jennifer M. Murphy, K. N. Houk, and Yong Liang: “Origins of Halogen Effects in Bioorthogonal Sydnone Cycloadditions,” Chem. Commun. 2018, 54, 5082-5085. 18. K. N. Houk and Fang Liu: “John D. Roberts, his beginnings at UCLA, his transformation of physical organic chemistry, and his impact on science,” J. Phys. Org. Chem. 2018, DOI: 10.1002/poc.3810. 17. Masao Ohashi, Fang Liu, Yang Hai, Mengbin Chen, Man-cheng Tang, Zhongyue Yang, Michio Sato, Kenji Watanabe, K. N. Houk, and Yi Tang: “SAM-Dependent Enzyme-Catalyzed Pericyclic Reactions in Natural Product Biosynthesis,” Nature, 2017, 549, 502-506. 16. Fang Liu, Yong Liang, and K. N. Houk: “Bioorthogonal Cycloadditions: Computational Analysis with the Distortion/Interaction Model, and Prediction of Reactivities,”Acc. Chem. Res., 2017, 50, 2297-2308. 15. Ilke Ugur, Sesil Agopcan Cinar, Burcu Dedeoglu, Viktorya Aviyente, M. Frederick Hawthorne, Peng Liu, Fang Liu, K. N. Houk, and Gonzalo Jimenez-Oses: "1,3-Dipolar Cycloaddition Reactions of Low-Valent Rhodium and Iridium Complexes with Arylnitrile NOxides," J. Org. Chem., 2017, 82, 5096-5101. 14. K. N. Houk and Fang Liu: "Holy Grails for Computational Organic Chemistry and Bichemistry," Acc. Chem. Res., 2017, 50, 539-543. 13. Abing Duan, Peiyuan Yu, Fang Liu, Huang Qiu, Feng Long Gu, Michael P. Doyle, and K. N. Houk: "Diazo Esters as Dienophiles in Intramolecular (4 + 2) Cycloadditions: Computational Explorations of Mechanism," J. Am. Chem. Soc., 2017, 139, 2766-2770. 12. Xia Yu, Fang Liu, Yi Zou, Man-Cheng Tang, Leibniz Hang, K. N. Houk, and Yi Tang: "Biosynthesis of Strained Piperazine Alkaloids: Uncovering the Concise Pathway of Herquline A," J. Am. Chem. Soc., 2016, 138, 13529-13532. 11. Yun-Fang Yang, Yong Liang, Fang Liu, and K. N. Houk: "Diels-Alder Reactivities of Benzene, Pyridine, and Di-, Tri-, and Tetrazines: The Roles of Geometrical Distortions and Orbital Interactions," J. Am. Chem. Soc., 2016, 138, 1660-1667. 10. David N. Kamber, Yong Liang, Robert J. Blizzard, Fang Liu, Ryan A. Mehl, K. N. Houk, and Jennifer A. Prescher: "1,2,4-Triazines Are Versatile Bioorthogonal Reagents," J. Am. Chem. Soc., 2015, 137, 8388-8391. 9. Lisa Tork, Gonzalo Jimenez-Oses, Charles Doubleday, Fang Liu, and K. N. Houk: "Molecular Dynamics of the Diels-Alder Reactions of Tetrazines with Alkenes and N2 Extrusions from Adducts," J. Am. Chem. Soc., 2015, 137, 4749-4758. 8. Fang Liu, Yong Liang, and K. N. Houk: "Theoretical Elucidation of the Origins of Substituent and Strain Effects on the Rates of Diels-Alder Reactions of 1,2,4,5-Tetrazines," J. Am. Chem. Soc., 2014, 136, 11483-11493. 7. Fang Liu, Roger C. Helgeson, and K. N. Houk: "Building on Cram's Legacy: Stimulated Gating in Hemicarcerands," Acc. Chem. Res., 2014, 47, 2168-2176. 6. Denisse de Loera, Fang Liu, K. N. Houk, and Miguel A. Garcia-Garibay: "Aziridine Nitrogen Inversion by Dynamic NMR: Activation Parameters in a Fused Bicyclic Structure," J. Org. Chem., 2013, 78, 11623-11636. 5. Fang Liu, Hao Wang, and Kendall N. Houk: "Gating in Host-Guest Chemistry," Curr. Org. Chem., 2013, 17, 1470-1480. 4. Fang Liu, Robert S. Paton, Seonah Kim, Yong Liang, and K. N. Houk: "Diels-Alder Reactivities of Strained and Unstrained Cycloalkenes with Normal and Inverse-ElectronDemand- Dienes: Activation Barriers and Distortion/Interaction Analysis," J. Am. Chem. Soc., 2013, 135, 15642-15649. 3. Hao Wang, Fang Liu, Roger C. Helgeson, Kendall N. Houk: "Reversible Photochemically Gated Transformation of a Hermicarcerand to a Carcerand," Angew. Chem. Int. Ed., 2012, 52, 655-659. 2. Yong Liang, Joel L. Mackey, Steven A. Lopez, Fang Liu, and K. N. Houk: "Control and Design of Mutual Orthogonality in Bioorthogonal Cycloadditions," J. Am. Chem. Soc., 2012, 134, 17904-17907. 1. Fang Liu, Hao Wang, and K. N. Houk: "Gated Container Molecules," Sci. China. Chem., 2011, 54, 2038-2044. 书籍章节 K. N. Houk, Fang Liu, Yun-Fang Yang, Xin Hong: Applied Theoretical Organic Chemistry, Chapter 13: The Distortion/Interaction Model for Analysis of Activation Energies of Organic Reactions, pp 371-402. Editor: Dean J. Tantillo. World Scientific, 2018.

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