Huttley, Gavin - The Australian National University

个人简介

Professor Gavin Huttley is a group leader in the Research School of Biology at the Australian National University. He obtained a B.Sc (Hons I) from Macquarie University in Sydney, a PhD in Molecular Population Genetics from the University of California, Riverside and undertook postdoctoral research in the Laboratory of Genomic Diversity, National Cancer Institute (USA). He is a recipient of the Howard Florey Young Investigator award. Professor Huttleys research is focussed on genome decryption — identifying regions of the genome which encode functions that influence susceptibility to disease — through analysis of genetic variation

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Padovan, A, Patel, H, Chuah, A et al 2015, 'Transcriptome Sequencing of Two Phenotypic Mosaic Eucalyptus Trees Reveals Large Scale Transcriptome Re-Modelling', PLOS ONE (Public Library of Science), vol. 10, no. 5, pp. 1-20. Kaehler, B, Yap, V, Zhang, R et al 2015, 'Genetic distance for a general non-stationary markov substitution process', Systematic Biology, vol. 64, no. 2, pp. 281-293. Maitip, J, Trueman, H, Kaehler, B et al 2015, 'Folding behavior of four silks of giant honey bee reflects the evolutionary conservation of aculeate silk proteins', Insect Biochemistry and Molecular Biology, vol. 59, pp. 72-79. Engelthaler, D, Hicks, N, Gillece, J et al 2014, 'Cryptococcus gattii in North American Pacific Northwest: Whole-Population Genome Analysis Provides Insights into Species Evolution and Dispersal', mBio, vol. 5, no. 4. Kitahara, M, Lin, M, Foret, S et al 2014, 'The ''Naked Coral'' Hypothesis revisited - evidence for and against scleractinian monophyly', PLOS ONE (Public Library of Science), vol. 9, no. 4. Da Paz Filho, G, Boguszewski, M, Mastronardi, C et al 2014, 'Whole Exome Sequencing of Extreme Morbid Obesity Patients: Translational Implications for Obesity and Related Disorders', GENES, vol. 5, no. 3, pp. 709-725. Ye, Y, Woolfit, M, Huttley, G et al 2013, 'Infection with a Virulent Strain of Wolbachia Disrupts Genome Wide-Patterns of Cytosine Methylation in the Mosquito Aedes aegypti', PLOS ONE (Public Library of Science), vol. 8, no. 6. Verbyla, K, Yap, V, Pahwa, A et al 2013, 'The Embedding Problem for Markov Models of Nucleotide Substitution', PLOS ONE (Public Library of Science), vol. 8, no. 7. Casewell, N, Huttley, G & Wuster, W 2012, 'Dynamic evolution of venom proteins in squamate reptiles', Nature Communications, vol. 3, pp. 1-10. Bellani, M, Epps, J & Huttley, G 2012, 'A Comparison of Periodicity Profile Methods for Sequence Analysis', IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS 2012), IEEE Engineering in Medicine and Biology Society, Washington DC USA, p. 4. Nekrasov, M, Amrichova, J, Parker, B et al., 'Histone H2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics', Nature Structural and Molecular Biology. 2012, vol. 19, no. 11, pp. 1076-1083. Soboleva TA, Nekrasov M, Pahwa A, Williams R, Huttley GA, Tremethick DJ. 'A unique H2A histone variant occupies the transcriptional start site of active genes', Nature Structural and Molecular Biology. 2012 Jan; 19(1): 25-30. Epps, J, Ying, H & Huttley, G 2011, 'Statistical methods for detecting periodic fragments in DNA sequence data', Biology Direct, vol. 6, no. 21, p. 16. Ying, H & Huttley, G 2011, 'Exploiting CpG hypermutability to identify phenotypically significant variation within human protein coding genes', Genome Biology and Evolution, vol. 3, no. 1, pp. 938-949. Sammut, R & Huttley, G 2011, 'Regional Context in the Alignment of Biological Sequence Pairs', Journal of Molecular Evolution, vol. 72, no. 2, pp. 147-159. Yap, V, Lindsay, H, Easteal, S et al 2010, 'Estimates of the effect of natural selection on protein-coding content', Molecular Biology and Evolution, vol. 27, no. 3, pp. 726-34. Ying, H, Epps, J, Williams, R et al 2010, 'Evidence that localized variation in primate sequence divergence arises from an influence of nucleosome placement on DNA repair', Molecular Biology and Evolution, vol. 27, no. 3, pp. 637-649. Caporaso, J, Kuczynski, J, Stombaugh, J et al 2010, 'QIIME allows analysis of high-throughput community sequencing data', Nature Methods: techniques for life scientists and chemists, vol. 7, no. 5, pp. 335-336. Simpson, N, Gatenby, P, Wilson, A, Malik, S, Fulcher, DA, Tangye, SG, Manku, H,Vyse, TJ, Roncador, G, Huttley, G, Goodnow, CC, Vinuesa, CG, Cook, MC, 2010, 'Expansion of Circulating T Cells Resembling Follicular Helper T Cells Is a Fixed Phenotype That Identifies a Subset of Severe Systemic Lupus Erythematosus', Arthritis & Rheumatism, vol. 62, no. 1, pp. 234-244. Huttley, G 2009, 'Do genomic datasets resolve the correct relationship among the placental, marsupial and monotreme lineages?', Australian Journal of Zoology, vol. 57, pp. 167-174.