个人简介
Stefan studied Biochemistry at the University of Tuebingen/Germany from 1981 to 1986. He completed his Masters in 1987 and moved to the Research Center in Juelich where he worked on amino acid producing bacteria during his PhD. He was awarded his PhD in 1991 and moved to the University of Illinois in Chicago as a research fellow of the German Science Foundation. In 1993 he was appointed as Junior Lecturer at the University of Tuebingen in the Institute of Physiological Chemistry. In 1998 Stefan was promoted to Senior Lecturer and moved to the Institute of Physiology at the University of Tuebingen. In 2000 Stefan moved to ANU as a Senior Lecturer in the School of Biochemistry and Molecular Biology. He was promoted to Associate Professor in 2006 and to full Professor in 2008. Stefan was treasurer and council member of the Australian Physiological Society from 2005-2009
研究领域
Membrane transporters in health and disease
近期论文
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Tumer, E., Broer, A., Balkrishna, S., Julich, T. and Broer, S. (2013) Enterocyte-specific regulation of the apical nutrient transporter SLC6A19 (B(0)AT1) by transcriptional and epigenetic networks. The Journal of biological chemistry. 288, 33813-33823
Yabas, M., Teh, C. E., Frankenreiter, S., Lal, D., Roots, C. M., Whittle, B., Andrews, D. T., Zhang, Y., Teoh, N. C., Sprent, J., Tze, L. E., Kucharska, E. M., Kofler, J., Farell, G. C., Broer, S., Goodnow, C. C. and Enders, A. (2011) ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes. Nat Immunol. 12, 441-449
Broer, S. and Palacin, M. (2011) The role of amino acid transporters in inherited and acquired diseases. Biochem J. 436, 193-211
Broer, A., Juelich, T., Vanslambrouck, J. M., Tietze, N., Solomon, P. S., Holst, J., Bailey, C. G., Rasko, J. E. and Broer, S. (2011) Impaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse. J Biol Chem. 286, 26638-26651
Bailey, C. G., Ryan, R. M., Thoeng, A. D., Ng, C., King, K., Vanslambrouck, J. M., Auray-Blais, C., Vandenberg, R. J., Broer, S. and Rasko, J. E. (2011) Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria. J Clin Invest. 121, 446-453
Kowalczuk, S., Broer, A., Tietze, N., Vanslambrouck, J. M., Rasko, J. E. and Broer, S. (2008) A protein complex in the brush-border membrane explains a Hartnup disorder allele. Faseb J. 22, 2880-2887
Seow, H. F., Broer, S., Broer, A., Bailey, C. G., Potter, S. J., Cavanaugh, J. A. and Rasko, J. E. (2004) Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19. Nat Genet. 36, 1003-1007
Broer, A., Klingel, K., Kowalczuk, S., Rasko, J. E., Cavanaugh, J. and Broer, S. (2004) Molecular Cloning of Mouse Amino Acid Transport System B0, a Neutral Amino Acid Transporter Related to Hartnup Disorder. J Biol Chem. 279, 24467-24476