Abell, Andrew D. - University of Adelaide

个人简介

2014 Adelaide Node Leader Centre for Nanosale BioPhotonics (CNBP) 2013 - 2014 Head of School of Chemistry and Physics The University of Adelaide 2011 Chief Scientific Advisor Calpain Therapeutics 2007 Professor University of Adelaide 2007 Adjunct Professor University of Canterbury 2007 Adjunct Professor Lincoln University (New Zealand) 2001 - 2007 Professor University of Canterbury 1993 - 1994 Visiting Scientist and Fulbright Scientist SmithKline Beecham 1985 - 1987 Postdoctoral Fellow University of Cambridge

研究领域

The focus of our extended group is concerned with the design, synthesis, and exploitation of small molecule enzyme inhibitors and mimics of key biological compounds. These compounds provide a basis of new therapeutics for the treatment of cancer and other diseases, as well as probes to study key metabolic processes such as electron transfer. They can also be attached to surfaces to provide functional materials and biosensors.

近期论文

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Pan, X., Zhao, J., Qian, G., Zhang, X., Ruan, Y., Abell, A., & Ebendorff-Heidepriem, H. (2020). Mechanistic insight into the non-hydrolytic sol-gel process of tellurite glass films to attain a high transmission. RSC Advances, 10(4), 2404-2415. Yu, J., Horsley, J. R., & Abell, A. D. (2020). Unravelling electron transfer in peptide-cation complexes: a model for mimicking redox centres in proteins.. Phys Chem Chem Phys. Law, C. S., Lim, S. Y., Liu, L., Abell, A. D., Marsal, L. F., & Santos, A. (2020). Realization of high-quality optical nanoporous gradient-index filters by optimal combination of anodization conditions.. Nanoscale. Horsfall, A. J., Abell, A. D., & Bruning, J. (2020). Targeting PCNA with peptide mimetics for therapeutic purposes. ChemBioChem, 21(4), 442-450. Lee, K., Tieu, W., Blanco-Rodriguez, B., Paparella, A., Yu, J., Hayes, A., . . . Abell, A. (2019). Sulfonamide-based inhibitors of biotin protein ligase as new antibiotic leads. ACS Chemical Biology, 14(9), 1990-1997. Liu, L., Lim, S. Y., Law, C. S., Jin, B., Abell, A. D., Ni, G., & Santos, A. (2019). Light-confining semiconductor nanoporous anodic alumina optical microcavities for photocatalysis. Journal of Materials Chemistry A, 7(39), 22514-22529. Guo, C., Yu, J., Horsley, J. R., Sheves, M., Cahen, D., & Abell, A. D. (2019). Backbone-constrained peptides: temperature and secondary structure affect solid-state electron transport. Journal of Physical Chemistry B, 123(51), 10951-10958. Bachhuka, A., Heng, S., Vasilev, K., Kostecki, R., Abell, A., & Ebendorff-Heidepriem, H. (2019). Surface Functionalization of Exposed Core Glass Optical Fiber for Metal Ion Sensing.. Sensors, 19, 1829. Schumann, N., Bruning, J., Marshall, A., & Abell, A. (2019). The role of N-terminal heterocycles in hydrogen bonding to α-chymotrypsin. Bioorganic and Medicinal Chemistry Letters, 29(3), 396-399. Pehere, A. D., Nguyen, S., Garlick, S. K., Wilson, D. W., Hudson, I., Sykes, M. J., . . . Abell, A. D. (2019). Tripeptide analogues of MG132 as protease inhibitors. Bioorganic and Medicinal Chemistry, 27(2), 436-441. Bachhuka, A., Heng, S., Vasilev, K., Kostecki, R., Abell, A., & Ebendorff-Heidepriem, H. (2019). Surface functionalization of exposed core glass optical fiber for metal ion sensing. Sensors, 19(8), 1-8. Lim, S., Law, C., Markovic, M., Marsal, L., Voelcker, N., Abell, A., & Santos, A. (2019). Rational management of photons for enhanced photocatalysis in structurally-colored nanoporous anodic alumina photonic crystals. ACS Applied Energy Materials, 2(2), 1169-1184. Peddie, V., & Abell, A. (2019). Photocontrol of peptide secondary structure through non-azobenzene photoswitches. Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 40, 1-20. Lim, S. Y., Law, S., Liu, L., Markovic, M., Abell, A. D., & Santos, A. (2019). Integrating surface plasmon resonance and slow photon effects in nanoporous anodic alumina photonic crystals for photocatalysis. Catalysis Science and Technology, 9(12), 3158-3176. Heng, S., Zhang, X., Pei, J., Adwal, A., Reineck, P., Gibson, B., . . . Abell, A. (2019). Spiropyran-based nanocarrier: a new Zn²⁺-responsive delivery system with real-time intracellular sensing capabilities. Chemistry - A European Journal, 25(3), 854-862. Law, S., Lim, S., Macalincag, R., Abell, A., & Santos, A. (2018). Light-confining nanoporous anodic alumina microcavities by apodized stepwise pulse anodization. ACS Applied Nano Materials, 1(9), 4418-4434. Zhang, X., Heng, S., Pei, J., Morey, J., McDevitt, C., & Abell, A. (2018). A liposomal platform for sensing of extracellular analytes near cells. Biosensors, 8(4), 1-11. Marshall, A., Keiller, B., Pederick, J., Abell, A., & Bruning, J. (2018). Crystal structure of bovine alpha-chymotrypsin in space group P65. Crystals, 8(12), 460. Wegener, K., Mcgrath, A., Dixon, N., Oakley, A., Scanlon, D., Abell, A., & Bruning, J. (2018). Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp [Cover Profile]. Chemistry - A European Journal, 24(44), 11238. Paparella, A., Feng, J., Blanco-Rodriguez, B., Feng, Z., Phetsang, W., Blaskovich, M., . . . Abell, A. (2018). A template guided approach to generating cell permeable inhibitors of Staphylococcus aureus biotin protein ligase. Tetrahedron, 74(12), 1175-1183. Paparella, A., Lee, K., Hayes, A., Feng, J., Feng, Z., Cini, D., . . . Abell, A. (2018). Halogenation of biotin protein ligase inhibitors improves whole cell activity against Staphylococcus aureus. ACS infectious diseases, 4(2), 175-184.