Jackson, Colin - The Australian National University

个人简介

Dr Colin Jackson has held research positions at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) and was a visiting research fellow at the Weizmann Institute of Science (Rehovot, Israel) and a Marie Curie Research Fellow at the Institut de Biologie Structurale (Grenoble, France), before his appointment as a Senior Lecturer at the Research School of Chemistry

研究领域

Chemical & structural biology

近期论文

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Mabbitt, P, Correy, G, Fraser, N et al 2016, 'Conformational Disorganization within the Active Site of a Recently Evolved Organophosphate Hydrolase Limits Its Catalytic Efficiency', Biochemistry, vol. 55, no. 9, pp. 1408-1417. Greening, C, Biswas, A, Carere, C et al 2016, 'Genomic and metagenomic surveys of hydrogenase distribution indicate H2 is a widely utilised energy source for microbial growth and survival', The International Society of Microbial Ecology, vol. 10, no. 5, pp. 761-777. Fraser, N, Liu, J, Mabbitt, P et al 2016, 'Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability', Journal of Molecular Biology, pp. -. Sugrue, E, Fraser, N, Hopkins, D et al 2015, 'Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to synthetic compounds: the molinate and diuron hydrolases', Applied and Environmental Microbiology, vol. 8, no. 7, pp. 2612-2624. Kaltenbach, M, Jackson, C, Campbell, E et al 2015, 'Reverse evolution leads to genotypic incompatibility despite functional and active site convergence', eLife, vol. 4, pp. 1-20. Van Benschoten, A, Afonine, P, Terwilliger, T et al 2015, 'Predicting X-ray diffuse scattering from translation-libration-screw structural ensembles', Acta Crystallographica Section D: Biological Crystallography, vol. D71, pp. 1657-1667. Whitfield, J, Zhang, W, Herde, M et al 2015, 'Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction', Protein Science, vol. 24, pp. 1412-1422. Riley, B, Broendum, S, Reboul, C et al 2015, 'Dynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyC', PLOS ONE (Public Library of Science), vol. 10, pp. 1-17. Banwell, M, Buckler, J, Jackson, C et al 2015, 'Devising New Syntheses of the Alkaloid Galanthamine, a Potent and Clinically Deployed Inhibitor of Acetylcholine Esterase', Strategies and Tactics in Organic Synthesis, vol. 11, pp. 29-50. Ahmed, H, Carr, P, Lee, B et al 2015, 'Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria', Journal of Molecular Biology, vol. 427, no. 22, pp. 3554-3571. Jackson, C, Carville, A, Ward, J et al 2014, 'Use of OpdA, an organophosphorus (OP) hydrolase, prevents lethality in an African green monkey model of acute OP poisoning', Toxicology, vol. 317, pp. 1-5. Naqvi, T, Warden, A, French, N et al 2014, 'A 5000-fold increase in the specificity of a bacterial phosphotriesterase for malathion through combinatorial active site mutagenesis', PLOS ONE (Public Library of Science), vol. 9, no. 4, pp. e94177/1-7. Jackson, C, Coppin, C, Carr, P et al 2014, '300-Fold Increase in Production of the Zn2+ -Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme Stabilization', Applied and Environmental Microbiology, vol. 80, no. 13, pp. 4003-4011. Lan, P, Jackson, C, Banwell, M et al 2014, 'Synthesis of a D-ring isomer of galanthamine via a radical-based Smiles rearrangement reaction', Journal of Organic Chemistry, vol. 79, no. 14, pp. 6759-6764. Carr, P, Ewens, C, Dai, J et al 2014, 'Crystal structure of the mouse interleukin-3 ?2-receptor: insights into interleukin-3 binding and receptor activation', Biochemical Journal, vol. 463, no. 3, pp. 393-403. Tokuriki, N & Jackson, C 2014, 'Enzyme dynamics and engineering: one step at a time', Chemistry and Biology, vol. 21, no. 10, pp. 1259-1260. Carruthers, T, Carr, P, Loh, C et al 2014, 'Iron(III) located in the dinuclear metallo-beta-lactamase IMP-1 by pseudocontact shifts', Angewandte Chemie International Edition, vol. 53, no. 51, pp. 14269-14272. Jackson, C, Liu, J, Carr, P et al 2013, 'Structure and function of an insect ?±-carboxylesterase (?±Esterase7) associated with insecticide resistance', PNAS - Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 25, pp. 10177-10182. Zhang, W, Otting, G & Jackson, C 2013, 'Protein engineering with unnatural amino acids', Current Opinion in Structural Biology, vol. 23, no. 4, pp. 581-587. Noor, S, Taylor, M, Russell, R et al 2012, 'Intramolecular epistasis and the evolution of a new enzymatic function', PLoS ONE (Public Library of Science), vol. 7, no. 6, pp. e39822/1-11.