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个人简介

Ph.D. 1987 University of Sydney D.Sc. 2002 University of Sydney Postdoctoral Fellow, Université Louis Pasteur, Strasbourg, France 1986-1988 Ramsay Memorial Fellow, Cambridge University, UK, 1989-1989 Lecturer (1990), Senior Lecturer (1994) Associate Professor (1999) Professor (2005) University of Sydney DNA Programme Leader, CRC for Molecular Engineering, 1992-1998 RACI Rennie Medal, 1993; RACI Biota Medal for Medicinal Chemistry, 1995 RACI Nyholm Youth Lecturer, 1999 Vice-Chancellor's Award for Excellence in Postgraduate Supervision, 2002 Deputy Head, School of Chemistry, 2000-2005 Associate Dean for Postgraduate Research, Faculty of Science, University of Sydney, 2000-2004 Member of ARC College of Experts, 2004-2006 Dean of Graduate Research & Professor of Chemistry, UNSW, 2005-2008 Pro Vice-Chancellor (Research Strategy) & Dean of Graduate Research, UNSW April 2008 - 2009 Pro Vice-Chancellor (Research) 2010-2012 Deputy Vice-Chancellor (Research) at ANU since June 2012 Visiting Professorial Fellow UNSW 2012-2015

研究领域

Medicinal and biological chemistry

Antifreeze Proteins and Glycoproteins Ligand-DNA Interactions

近期论文

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Durai, C & Harding, P 2011, 'Targeting nucleic acids using dynamic combinatorial chemistry', Australian Journal of Chemistry, vol. 64, no. 6, pp. 671-680. C. Sherman Durai and M. M. Harding, Targeting Nucleic Acids Using Dynamic Combinatorial Chemistry, Aust. J. Chem. 2011, 64, 671-680. Schilter, D, Clegg, J, Harding, P et al 2010, 'Platinum(II) and palladium(II) metallomacrocycles derived from cationic 4,4'-bipyridinium, 3-aminopyrazinium and 2-aminopyrimidinium ligands', Dalton Transactions, vol. 39, no. 1, pp. 239-247. Schilter, D, Urathamakul, T, Harding, P et al 2010, 'ESI-MS and thermal melting studies of nanoscale platinum(II) metallomacrocycles with DNA', Dalton Transactions, vol. 39, no. 46, pp. 11263-11271. Hunter, L, Condie, G & Harding, P 2010, 'Reversible aqueous metathesis reactions for potential application in dynamic combinatorial chemistry', Tetrahedron Letters, vol. 51, no. 38, pp. 5064-5067. Garner, J & Harding, P 2010, 'Design and Synthesis of Antifreeze Glycoproteins and Mimics', ChemBioChem, vol. 11, no. 18, pp. 2489-2498. L. Hunter, G. Condie and M. M. Harding, Reversible Aqueous Metathesis Chemistry for potential applications in dynamic combinatorial chemistry, Tetrahedron Lett., 2010, 51, 5064-5067 Manohari Abeysinghe, p, Han, Y & Harding, P 2009, 'Oxidation of threonine residues with IBX reagents', Tetrahedron Letters, vol. 50, no. 21, pp. 2601-2604. Garner, J, Jolliffe, K, Harding, P et al 2009, 'Synthesis of homogeneous antifreeze glycopeptides via a ligation-desulfurization strategy', Chemical Communications, vol. 45, no. 45, pp. 6925-6927. J. Garner, K. A. Jolliffe, M. M. Harding and R. J. Payne, Synthesis of homogeneous antifreeze glycopeptides via a ligation-desulfurisation strategy, Chem. Commun., 2009, 6925-6927 P. M. Abeysinghe, Y. Han and M. M .Harding, Oxidation of Threonine residues in Peptides with Hypervalent Iodine Reagents, Tetrahedron Letters., 2009, 50, 2601-2604 Garner, J, Inglis, S, Hook, J et al 2008, 'A solid-state NMR study of the interaction of fish antifreeze proteins with phospholipid membranes', European Biophysics Journal, vol. 37, no. 6, pp. 1031-1038. Buck, D, Manohari Abeysinghe, p, Cullinane, C et al 2008, 'Inclusion complexes of the antitumor metallocenes Cp2MCl2 (M = Mo, Ti) with cucurbit[n]urils', Dalton Transactions, vol. 1, no. 17, pp. 2328-2334. Harding, P & Manohari Abeysinghe, p 2007, 'Antitumor bis(cyclopentadienyl) metal complexes: titanocene and molybdocene dichloride and derivatives', Dalton Transactions, vol. 1, no. 32, pp. 3474-3482. Garner, J & Harding, P 2007, 'Design and synthesis of a-helical peptides and mimetics', Organic and Biomolecular Chemistry, vol. 5, no. 22, pp. 3557-3720. Waern, J, Turner, P & Harding, P 2006, 'Synthesis and Hydrolysis of Thiol Derivatives of Molybdocene Dichloride Incorporating Electron-Withdrawing Substituents', Organometallics, vol. 25, no. 14, pp. 3417-3421. Campbell, K, Foster, A, Dillon, C et al 2006, 'Genotoxicity and transmission electron microscopy studies of molybdocene dichloride', Journal of Inorganic Biochemistry, vol. 100, no. 7, pp. 1194-1198. Waern, J, Harris, H, Lai, B et al 2005, 'Intracellular mapping of the distribution of metals derived from the antitumor metallocenes', Journal of Biological Inorganic Chemistry, vol. 10, no. 5, pp. 443-452. Kwan, A, Fairley, K, Anderberg, P et al 2005, 'Solution Structure of a Recombinant Type I Sculpin Antifreeze Protein', Biochemistry, vol. 44, no. 6, pp. 1980-1988. Waern, J, Dillon, C & Harding, P 2005, 'Organometallic Anticancer Agents: Cellular Uptake and Cytotoxicity Studies on Thiol Derivatives of the Antitumor Agent Molybdocene Dichloride', Journal of Medicinal Chemistry, vol. 48, no. 6, pp. 2093-2099.

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