Rnjak-Kovacina, Jelena - University of New South Wales - Graduate School of Biomedical Engineering

个人简介

Postdoctoral scholar- Department of Biomedical Engineering, Tufts University, Boston, USA, 2011-2013 Research area: Development of novel silk-based biomaterials for tissue engineering and regenerative medicine, Supervisor: Prof David Kaplan Doctor of Philosophy, School of Molecular Bioscience, University of Sydney, 2011 Research area: Development of human elastin-based dermal substitutes for the treatment of severe burn injuries, Supervisor: Prof Antony Weiss Bachelor of Science (Molecular Biology & Genetics) (Honours I) (University Medal),University of Sydney, 2007

研究领域

Dr Rnjak-Kovacina’s research interests are at the interface of biology and engineering, focusing on the development of novel, biomimetic biomaterial platforms with tuneable biophysical and biochemical features that direct cellular behaviour and function. In particular, she works on developing strategies to promote vascular regeneration on biomaterials.

近期论文

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Ghezzi CE; Wang L; Behlau I; Rnjak-Kovacina J; Wang S; Goldstein MH; Liu J; Marchant JK; Rosenblatt MI; Kaplan DL, 2016, 'Degradation of silk films in multipocket corneal stromal rabbit models', Journal of Applied Biomaterials and Fundamental Materials, vol. 14, no. 3, pp. e266 - e276, http://dx.doi.org/10.5301/jabfm.5000274 Rnjak-Kovacina J; Wray LS; Burke KA; Torregrosa T; Golinski JM; Huang W; Kaplan DL, 2015, 'Lyophilized Silk Sponges: A Versatile Biomaterial Platform for Soft Tissue Engineering', ACS biomaterials science & engineering, vol. 1, no. 4, pp. 260 - 270, http://dx.doi.org/10.1021/ab500149p Chen Y; Lin Y; Davis KM; Wang Q; Rnjak-Kovacina J; Li C; Isberg RR; Kumamoto CA; Mecsas J; Kaplan DL, 2015, 'Robust bioengineered 3D functional human intestinal epithelium', Scientific Reports, vol. 5, http://dx.doi.org/10.1038/srep13708 Ghezzi CE; Rnjak-Kovacina J; Kaplan DL, 2015, 'Corneal Tissue Engineering: Recent Advances and Future Perspectives', Tissue Engineering Part B: Reviews, vol. 21, no. 3, pp. 278 - 287, http://dx.doi.org/10.1089/ten.teb.2014.0397 Zhang W; Wray LS; Rnjak-Kovacina J; Xu L; Zou D; Wang S; Zhang M; Dong J; Li G; Kaplan DL; Jiang X, 2015, 'Vascularization of hollow channel-modified porous silk scaffolds with endothelial cells for tissue regeneration', Biomaterials, vol. 56, pp. 68 - 77, http://dx.doi.org/10.1016/j.biomaterials.2015.03.053 Rnjak-Kovacina J; Desrochers TM; Burke KA; Kaplan DL, 2015, 'The Effect of Sterilization on Silk Fibroin Biomaterial Properties', Macromolecular Bioscience, http://dx.doi.org/10.1002/mabi.201500013 Lord MS; Farrugia BL; Rnjak-Kovacina J; Whitelock JM, 2015, 'Current serological possibilities for the diagnosis of arthritis with special focus on proteins and proteoglycans from the extracellular matrix', Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare, vol. 15, no. 1, pp. 77 - 95, http://dx.doi.org/10.1586/14737159.2015.979158 McNamara SL; Rnjak-Kovacina J; Schmidt DF; Lo TJ; Kaplan DL, 2014, 'Silk as a biocohesive sacrificial binder in the fabrication of hydroxyapatite load bearing scaffolds', Biomaterials, vol. 35, no. 25, pp. 6941 - 6953, http://dx.doi.org/10.1016/j.biomaterials.2014.05.013 Liu H; Wise SG; Rnjak-Kovacina J; Kaplan DL; Bilek MMM; Weiss AS; Fei J; Bao S, 2014, 'Biocompatibility of silk-tropoelastin protein polymers', Biomaterials, vol. 35, no. 19, pp. 5138 - 5147, http://dx.doi.org/10.1016/j.biomaterials.2014.03.024 Partlow BP; Hanna CW; Rnjak-Kovacina J; Moreau JE; Applegate MB; Burke KA; Marelli B; Mitropoulos AN; Omenetto FG; Kaplan DL, 2014, 'Highly tunable elastomeric silk biomaterials', Advanced Functional Materials, http://dx.doi.org/10.1002/adfm.201400526 Wu J; Rnjak-Kovacina J; Du Y; Funderburgh ML; Kaplan DL; Funderburgh JL, 2014, 'Corneal stromal bioequivalents secreted on patterned silk substrates', Biomaterials, vol. 35, no. 12, pp. 3744 - 3755, http://dx.doi.org/10.1016/j.biomaterials.2013.12.078 Ghezzi CE; Rnjak-Kovacina J; Weiss AS; Kaplan DL, 2013, 'Multifunctional silk-tropoelastin biomaterial systems', Israel Journal of Chemistry, vol. 53, no. 9-10, pp. 777 - 786, http://dx.doi.org/10.1002/ijch.201300082 Wise SG; Hiob MA; Ng MKC; Yeo GC; Weiss AS; Rnjak-Kovacina J; Kaplan DL, 2013, 'Tropoelastin: A versatile, bioactive assembly module', Acta Biomaterialia, http://dx.doi.org/10.1016/j.actbio.2013.08.003 Reddel CJ; Cultrone D; Rnjak-Kovacina J; Weiss AS; Burgess JK, 2013, 'Tropoelastin modulates TGF-β1-induced expression of VEGF and CTGF in airway smooth muscle cells', Matrix Biology, vol. 32, no. 7-8, pp. 407 - 413, http://dx.doi.org/10.1016/j.matbio.2013.04.003 Seib FP; Jones GT; Rnjak-Kovacina J; Lin Y; Kaplan DL, 2013, 'pH-Dependent Anticancer Drug Release from Silk Nanoparticles', Advanced healthcare materials, vol. 2, no. 12, pp. 1606 - 1611, http://dx.doi.org/10.1002/adhm.201300034 Rnjak-Kovacina J; Wray LS; Golinski JM; Kaplan DL, 2013, 'Arrayed Hollow Channels in Silk-Based Scaffolds Provide Functional Outcomes for Engineering Critically Sized Tissue Constructs', Advanced Functional Materials, http://dx.doi.org/10.1002/adfm.201302901 Wray LS; Rnjak-Kovacina J; Mandal BB; Schmidt DF; Gil ES; Kaplan DL, 2012, 'A silk-based scaffold platform with tunable architecture for engineering critically-sized tissue constructs', Biomaterials, vol. 33, no. 36, pp. 9214 - 9224, http://dx.doi.org/10.1016/j.biomaterials.2012.09.017 Rnjak-Kovacina J; Wise SG; Li Z; Maitz PKM; Young CJ; Wang Y; Weiss AS, 2012, 'Electrospun synthetic human elastin:collagen composite scaffolds for dermal tissue engineering', Acta Biomaterialia, vol. 8, no. 10, pp. 3714 - 3722, http://dx.doi.org/10.1016/j.actbio.2012.06.032 Rnjak J; Wise SG; Mithieux SM; Weiss AS, 2011, 'Severe burn injuries and the role of Elastin in the design of dermal substitutes', Tissue Engineering Part B: Reviews, vol. 17, no. 2, pp. 81 - 91, http://dx.doi.org/10.1089/ten.teb.2010.0452