研究领域

Clinical Research, Pharmacology, Metabolism, Inflammation, Diabetes

Interests span the general area of conducting of clinical trials of new medicines (design, ethical issues, endpoints including surrogate outcomes), including complementary medicines complementary medicines. A particular focus is on arthritis, gout and diabetes. Drug metabolism and disposition and pharmacokinetics are also interests.

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Rasheed H; McKinney C; Stamp LK; Dalbeth N; Topless RK; Day R; Kannangara D; Williams K; Smith M; Janssen M; Jansen TL; Joosten LA; Radstake TR; Riches PL; Tausche AK; Lioté F; Lu L; Stahl EA; Choi HK; So A; Merriman TR, 2016, 'The toll-like receptor 4 (TLR4) variant rs2149356 and risk of gout in European and polynesian sample sets', PLoS One, vol. 11, no. 1, http://dx.doi.org/10.1371/journal.pone.0147939 Kannangara DRW; Phipps-Green AJ; Dalbeth N; Stamp LK; Williams KM; Graham GG; Day RO; Merriman TR, 2016, 'Hyperuricaemia: Contributions of urate transporter ABCG2 and the fractional renal clearance of urate', Annals of the Rheumatic Diseases, vol. 75, no. 7, pp. 1363 - 1366, http://dx.doi.org/10.1136/annrheumdis-2015-208111 Kannangara DRW; Graham GG; Williams KM; Day RO, 2016, 'Effect of xanthine oxidase inhibitors on the renal clearance of uric acid and creatinine', Clinical Rheumatology, pp. 1 - 2, http://dx.doi.org/10.1007/s10067-015-3165-x Vaccher S; Kannangara DR; Baysari MT; Reath J; Zwar N; Williams KM; Day RO, 2016, 'Barriers to Care in Gout: From Prescriber to Patient.', Journal of Rheumatology, vol. 43, no. 1, pp. 144 - 149, http://dx.doi.org/10.3899/jrheum.150607 Hmar RC; Kannangara DRW; Ramasamy SN; Baysari MT; Williams KM; Day RO, 2015, 'Understanding and improving the use of allopurinol in a teaching hospital', Internal Medicine Journal, vol. 45, no. 4, pp. 383 - 390, http://dx.doi.org/10.1111/imj.12701 Merriman TR; Stamp LK; Dalbeth N; Topless R; Day R; Kannangara D; Williams K; Janssen M; Jansen T; Joosten LA; Radstake T; Riches PL; Tausche A-K; Liote F; So A; McKinney C, 2015, 'Epistatic Interaction of Functional Inflammasome Genetic Variants in Determining the Risk of Gout', Arthritis & Rheumatology, vol. 67, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000370860204715&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a McKinney C; Stamp LK; Dalbeth N; Topless RK; Day RO; Kannangara DRW; Williams KM; Janssen M; Jansen TL; Joosten LA; Radstake TR; Riches PL; Tausche AK; Lioté F; So A; Merriman TR, 2015, 'Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout', Arthritis Research and Therapy, http://dx.doi.org/10.1186/s13075-015-0802-3 Duong JK; Kumar SS; Furlong TJ; Kirkpatrick CM; Graham GG; Greenfield JR; Williams KM; Day RO, 2015, 'The pharmacokinetics of metformin and concentrations of haemoglobin A1C and lactate in Indigenous and non-Indigenous Australians with type 2 diabetes mellitus', British Journal of Clinical Pharmacology, vol. 79, no. 4, pp. 617 - 623, http://dx.doi.org/10.1111/bcp.12525 Ghosh D; Williams KM; Graham GG; Nair P; Buscher H; Day RO, 2014, 'Multiple episodes of aspirin overdose in an individual patient: a case report', Journal of Medical Case Reports, vol. 8, pp. 374, http://dx.doi.org/10.1186/1752-1947-8-374 Ghosh D; Williams KM; Graham GG; Nair P; Buscher H; Day RO, 2014, 'Multiple episodes of aspirin overdose in an individual patient: A case report', Journal of Medical Case Reports, pp. 1 - 5, http://dx.doi.org/10.1186/1752-1947-8-374 Rasheed H; Topless R; Day R; Kannangara D; Williams K; Bradbury L; Brown M; Hill C; Lester S; Rischmueller M; Smith M; Andres M; Bardin T; Doherty M; Janssen M; Jansen T; Joosten L; Perez-Ruiz F; Radstake T; Riches PL; Roddy E; Tausche A-K; Stamp LK; Dalbeth N; Liote F; So A; McKinney C; Merriman TR, 2014, 'Association of the Toll-like Receptor 4 (TLR4) Gene with Gout.', Arthritis & Rheumatology, vol. 66, pp. S1294 - S1295, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344384906196&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a Chung WH; Chang WC; Stocker SL; Juo CG; Graham GG; Lee MHH; Williams KM; Tian YC; Juan KC; Wu YJJ; Yang CH; Chang CJ; Lin YJ; Day RO; Hung SI, 2014, 'Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: The impact of renal insufficiency, high plasma levels of oxypurinol and granulysin', Annals of the Rheumatic Diseases, http://dx.doi.org/10.1136/annrheumdis-2014-205577 Kannangara DRW; Ramasamy SN; Ray JE; Jones G; Graham GG; Williams KM; Day RO, 2013, 'An audit of a therapeutic drug monitoring service for allopurinol therapy', Therapeutic Drug Monitoring, vol. 35, no. 6, pp. 863 - 866, http://dx.doi.org/10.1097/FTD.0b013e318299920a Ramasamy SN; Korb-Wells CS; Kannangara DRW; Smith MWH; Wang N; Roberts DM; Graham GG; Williams KM; Day RO, 2013, 'Allopurinol hypersensitivity: A systematic review of all published cases, 1950-2012', Drug Safety, vol. 36, no. 10, pp. 953 - 980, http://dx.doi.org/10.1007/s40264-013-0084-0 Wong C; Kumar SS; Graham GG; Begg EJ; Chin PKL; Brett J; Ray JE; Marriott DJE; Williams KM; Day RO, 2013, 'Comparing dose prediction software used to manage gentamicin dosing', Internal Medicine Journal, vol. 43, no. 5, pp. 519 - 525, http://dx.doi.org/10.1111/imj.12067 Day R; Lee H; Graham G; Williams K, 2013, 'Benzbromarone: Availability for general prescribing in New Zealand (a response to letters by Dr Lance Gravatt on benzbromarone)', New Zealand Medical Journal, vol. 126, no. 1382, pp. 124 - 126 Brett J; Chong O; Graham GG; Ray JE; Marriott D; Williams KM; Day RO, 2013, 'Antifungal use and therapeutic monitoring of plasma concentrations of itraconazole in heart and lung transplantation patients', Therapeutic Drug Monitoring, vol. 35, no. 1, pp. 133 - 136, http://dx.doi.org/10.1097/FTD.0b013e318275fe69 Lee MHH; Stocker SL; Williams KM; Day RO, 2013, 'HLA-B*5801 should be used to screen for risk of Stevens-Johnson syndrome in family members of Han Chinese patients commencing allopurinol therapy', Journal of Rheumatology, vol. 40, no. 1, pp. 96 - 97, http://dx.doi.org/10.3899/jrheum.120803 Stocker SL; Mclachlan AJ; Savic RM; Kirkpatrick CM; Graham GG; Williams KM; Day RO, 2012, 'The pharmacokinetics of oxypurinol in people with gout', British Journal of Clinical Pharmacology, vol. 74, no. 3, pp. 477 - 489, http://dx.doi.org/10.1111/j.1365-2125.2012.04207.x Kannangara DRW; Roberts DM; Furlong TJ; Graham GG; Williams KM; Day RO, 2012, 'Oxypurinol, allopurinol and allopurinol-1-riboside in plasma following an acute overdose of allopurinol in a patient with advanced chronic kidney disease', British Journal of Clinical Pharmacology, vol. 73, no. 5, pp. 828 - 829, http://dx.doi.org/10.1111/j.1365-2125.2011.04147.x