Quek, Lake-Ee - University of New South Wales

研究领域

Cell Metabolism, Systems Biology

近期论文

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Martínez VS; Buchsteiner M; Gray P; Nielsen LK; Quek LE, 2015, 'Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism', Metabolic Engineering Communications, vol. 2, pp. 46 - 57, http://dx.doi.org/10.1016/j.meteno.2015.06.001 de Oliveira Dal'Molin CG; Quek LE; Saa PA; Nielsen LK, 2015, 'A multi-tissue genome-scale metabolic modeling framework for the analysis of whole plant systems', Frontiers in Plant Science, vol. 6, no. JAN, pp. 1 - 12, http://dx.doi.org/10.3389/fpls.2015.00004 Dal'Molin CGO; Quek LE; Palfreyman RW; Nielsen LK, 2014, 'Plant genome-scale modeling and implementation', Methods in Molecular Biology, vol. 1090, pp. 317 - 332, http://dx.doi.org/10.1007/978-1-62703-688-7_19 Arifin Y; Archer C; Lim SA; Quek LE; Sugiarto H; Marcellin E; Vickers CE; Krömer JO; Nielsen LK, 2014, 'Escherichia coli W shows fast, highly oxidative sucrose metabolism and low acetate formation', Applied Microbiology and Biotechnology, vol. 98, no. 21, pp. 9033 - 9044, http://dx.doi.org/10.1007/s00253-014-5956-4 Quek LE; Dietmair S; Hanscho M; Martínez VS; Borth N; Nielsen LK, 2014, 'Reducing Recon 2 for steady-state flux analysis of HEK cell culture', Journal of Biotechnology, vol. 184, pp. 172 - 178, http://dx.doi.org/10.1016/j.jbiotec.2014.05.021 Martínez VS; Quek LE; Nielsen LK, 2014, 'Network thermodynamic curation of human and yeast genome-scale metabolic models', Biophysical Journal, vol. 107, no. 2, pp. 493 - 503, http://dx.doi.org/10.1016/j.bpj.2014.05.029 Quek LE; Nielsen LK, 2014, 'A depth-first search algorithm to compute elementary flux modes by linear programming', BMC Systems Biology, vol. 8, no. 1, http://dx.doi.org/10.1186/s12918-014-0094-2 Arifin Y; Archer C; Lim S; Quek L-E; Sugiarto H; Marcellin E; Vickers CE; Krömer JO; Nielsen LK, 2014, 'Escherichia coli W shows fast, highly oxidative sucrose metabolism and low acetate formation', Applied Microbiology and Biotechnology, http://dx.doi.org/10.1007/s00253-014-5956-4 Turner J; Quek LE; Titmarsh D; Krömer JO; Kao LP; Nielsen L; Wolvetang E; Cooper-White J, 2014, 'Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrations', PLoS One, vol. 9, no. 11, http://dx.doi.org/10.1371/journal.pone.0112757 Martínez VS; Dietmair S; Quek LE; Hodson MP; Gray P; Nielsen LK, 2013, 'Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption', Biotechnology and Bioengineering, vol. 110, no. 2, pp. 660 - 666, http://dx.doi.org/10.1002/bit.24728 Dietmair S; Hodson MP; Quek LE; Timmins NE; Chrysanthopoulos P; Jacob SS; Gray P; Nielsen LK, 2012, 'Metabolite profiling of CHO cells with different growth characteristics', Biotechnology and Bioengineering, vol. 109, no. 6, pp. 1404 - 1414, http://dx.doi.org/10.1002/bit.24496 Dietmair S; Hodson MP; Quek LE; Timmins NE; Gray P; Nielsen LK, 2012, 'A multi-omics analysis of recombinant protein production in Hek293 cells', PLoS One, vol. 7, no. 8, http://dx.doi.org/10.1371/journal.pone.0043394 Licona-Cassani C; Marcellin E; Quek LE; Jacob S; Nielsen LK, 2012, 'Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production', Antonie van Leeuwenhoek: international journal of general and molecular microbiology, vol. 102, no. 3, pp. 493 - 502, http://dx.doi.org/10.1007/s10482-012-9783-2 Gomes de Oliveira Dal'Molin C; Quek LE; Palfreyman RW; Nielsen LK, 2011, 'AlgaGEM - a genome-scale metabolic reconstruction of algae based on the Chlamydomonas reinhardtii genome', BMC Genomics, vol. 12, no. SUPPL. 4, http://dx.doi.org/10.1186/1471-2164-12-S4-S5 Dal'Molin CGDO; Quek LE; Palfreyman RW; Brumbley SM; Nielsen LK, 2010, 'AraGEM, a genome-scale reconstruction of the primary metabolic network in Arabidopsis', Plant Physiology, vol. 152, no. 2, pp. 579 - 589, http://dx.doi.org/10.1104/pp.109.148817 Quek LE; Dietmair S; Krömer JO; Nielsen LK, 2010, 'Metabolic flux analysis in mammalian cell culture', Metabolic Engineering, vol. 12, no. 2, pp. 161 - 171, http://dx.doi.org/10.1016/j.ymben.2009.09.002 Dal'Molin CGDO; Quek LE; Palfreyman RW; Brumbley SM; Nielsen LK, 2010, 'C4GEM, a genome-scale metabolic model to study C4 plant metabolism', Plant Physiology, vol. 154, no. 4, pp. 1871 - 1885, http://dx.doi.org/10.1104/pp.110.166488 Kromer JO; Quek L, 2009, '13C-fluxomics: A tool for measuring metabolic phenotypes', Australian Biochemist, vol. 40, no. 3, pp. 17 - 20, http://asbmb.org.au/magazine/2009-December_Issue40-3/Technical%20Feature%204%20-%20Kromer.pdf Quek LE; Wittmann C; Nielsen LK; Krömer JO, 2009, 'OpenFLUX: Efficient modelling software for 13C-based metabolic flux analysis', Microbial Cell Factories, vol. 8, http://dx.doi.org/10.1186/1475-2859-8-25 Quek LE; Nielsen LK, 2008, 'On the reconstruction of the Mus musculus genome-scale metabolic network model.', Genome informatics. International Conference on Genome Informatics, vol. 21, pp. 89 - 100