Pather, Nalini - University of New South Wales

个人简介

Nalini Pather is a lecturer in the School of Medical Sciences. Her research is currently focussed on two areas: tissue repair and medical education. TISSUE REPAIR: This is particularly focussed on the relation between the processes of angiogenesis and tissue repair following muscle degeneration. There is strong evidence that the processes of angiogenesis and muscle regeneration share common cytokines and chemokines, and that these cytokines and chemokines are able to activate resident stem cell populations, causing them to migrate to and proliferate in the injured muscle bed where they are integral to the regenerating damaged tissue. More recent evidence suggests that the injured muscle secretes ‘myokines’ that direct these processes. Nalini's research group is focussing on elucidating the role of angiogenic cytokines and chemokines in orchestrating the repair of muscle following injury and in activating resident stem cell populations. An understanding of these mechanisms has potential for optimising and increasing the efficacy of stem cell and cytokine therapies for congenital diseases such as muscular dystrophies. In the long term, this data should aid in developing effective cytokine therapies for acute muscle injury (such as from trauma) and degenerative muscular diseases. This research presently focuses on muscle tissue and in future, will be expanded to include other solid organs, applying the principles and knowledge gained from muscle as a solid organ. MEDICAL EDUCATION: In the area of medical education, Nalini is particularly interested in student learning and assessment in the medical sciences. She is currently developing Adaptive eLearning tutorials in Anatomy to be used as a formative assessment tool. Adaptive eLearning tutorials provide a platform for formative assessment of students providing immediate feedback and opportunity to remediate gaps in knowledge. At an educator level, it has the potential to identify areas of troublesome knowledge for a cohort of students, and to evaluate student learning. Nalini is also investigating personality traits and learning styles and how these influence assessment performance in various modes of assessment. This research is aimed at developing sustainable and robust assessment methods for medicine and science students.

研究领域

Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

近期论文

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Yoo S; Dedova I; Pather N, 2015, 'An appraisal of the short lateral rotators of the hip joint', Clinical Anatomy, vol. 28, no. 6, pp. 800 - 812, http://dx.doi.org/10.1002/ca.22568 Štrkalj G; Pather N, 2014, 'A proposal for introducing a requirement to declare the provenience of cadavers in anatomy publications', Clinical Anatomy, http://dx.doi.org/10.1002/ca.22390 Lee AS; Anderson JE; Joya JE; Head SI; Pather N; Kee AJ; Gunning PW; Hardeman EC, 2013, 'Aged skeletal muscle retains the ability to fully regenerate functional architecture.', Bioarchitecture, vol. 3, no. 2, pp. 25 - 37, http://dx.doi.org/10.4161/bioa.24966 Štrkalj G; Pather N, 2013, 'Phillip V. Tobias as an anatomist', Clinical Anatomy, vol. 26, no. 4, pp. 423 - 429, http://dx.doi.org/10.1002/ca.22163 Olateju OI; Pather N; Kramer B, 2012, 'The proliferative effect of all-trans retinoic acid during wound healing: A compromised effect in the presence of dimethyl sulphoxide', Wound practice and research, vol. 20(4), no. 4, pp. 1 - 7 Pather N; Kramer B, 2012, 'Bulbine Natalensis and Bulbine Frutescens promote cutaneous wound healing', Journal of Ethnopharmacology, vol. 144, no. 3, pp. 523 - 532, http://dx.doi.org/10.1016/j.jep.2012.09.034 Strkalj G; Schroder T; Pather N; Solyali V, 2011, 'A preliminary assessment of the fifth-year chiropractic students' knowledge of anatomy', Journal of Alternative and Complementary Medicine, vol. 17, no. 1, pp. 63 - 66, http://dx.doi.org/10.1089/acm.2010.0157 Pather N; Viljoen AM; Kramer B, 2011, 'A biochemical comparison of the in vivo effects of Bulbine frutescens and Bulbine natalensis on cutaneous wound healing', Journal of Ethnopharmacology, vol. 133, no. 2, pp. 364 - 370, http://dx.doi.org/10.1016/j.jep.2010.10.007 Kramer B; Pather N; Ihunwo AO, 2008, 'Anatomy: The African spotlight unfurls', Anatomical Sciences Education, vol. 1, no. 5, pp. 231 - 232, http://dx.doi.org/10.1002/ase.47 Kramer B; Pather N; Ihunwo AO, 2008, 'Anatomy: Spotlight on Africa', Anatomical Sciences Education, vol. 1, no. 3, pp. 111 - 118, http://dx.doi.org/10.1002/ase.28 Pather N; Osman M, 2006, 'Landmarks of the facial nerve: Implications for parotidectomy', Surgical and Radiologic Anatomy: journal of clinical anatomy, vol. 28, no. 2, pp. 170 - 175, http://dx.doi.org/10.1007/s00276-005-0070-z Pather N; Partab P; Singh B; Satyapal KS, 2006, 'Cervico-thoracic ganglion: Its clinical implications', Clinical Anatomy, vol. 19, no. 4, pp. 323 - 326, http://dx.doi.org/10.1002/ca.20214 Pather N; Ramsey S, 2005, 'The aortic root: establishing the norm', The FASEB Journal, vol. 19, no. 4, pp. A246 - A247 Pather N; Singh B; Partab P; Ramsaroop L; Satyapal KS, 2004, 'The anatomical rationale for an upper limb sympathetic blockade: Preliminary report', Surgical and Radiologic Anatomy: journal of clinical anatomy, vol. 26, no. 3, pp. 178 - 181, http://dx.doi.org/10.1007/s00276-003-0209-8 Pather N; Partab P; Singh B; Satyapal KS, 2003, 'The sympathetic contributions to the cardiac plexus', Surgical and Radiologic Anatomy: journal of clinical anatomy, vol. 25, no. 3-4, pp. 210 - 215, http://dx.doi.org/10.1007/s00276-003-0113-2 Ramsaroop L; Singh B; Moodley J; Partab P; Pather N; Satyapal KS, 2003, 'A thoracoscopic view of the nerve of Kuntz.', Surgical Endoscopy: surgical and interventional techniques, vol. 17, no. 9, pp. 1498 Satyapal KS; Singh B; Partab P; Ramsaroop L; Pather N, 2003, 'Thoracoscopy: A New Era for Surgical Anatomy', Clinical Anatomy, vol. 16, no. 6, pp. 538 - 541, http://dx.doi.org/10.1002/ca.10174 Naidoo N; Partab P; Pather N; Moodley J; Singh B; Satyapal KS, 2001, 'Thoracic splanchnic nerves: Implications for splanchnic denervation', Journal of Anatomy, vol. 199, no. 5, pp. 585 - 590