研究领域

Animal Cell and Molecular Biology

My research focuses on the relationship between impaired cholesterol homeostasis and disease. Dynamic multi-technology approaches to understand - from single molecule systems to organs and whole body physiology.

近期论文

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Cochran BJ; Ryder WJ; Parmar A; Tang S; Reilhac A; Arthur A; Charil A; Hamze H; Barter PJ; Kritharides L; Meikle SR; Gregoire MC; Rye KA, 2016, 'In vivo PET imaging with [18F]FDG to explain improved glucose uptake in an apolipoprotein A-I treated mouse model of diabetes', Diabetologia, vol. 59, no. 9, pp. 1977 - 1984, http://dx.doi.org/10.1007/s00125-016-3993-5 Sultana A; Cochran BJ; Tabet F; Patel M; Torres LC; Barter PJ; Rye KA, 2016, 'Inhibition of inflammatory signaling pathways in 3T3-L1 adipocytes by apolipoprotein A-I', The FASEB Journal, vol. 30, no. 6, pp. 2324 - 2335, http://dx.doi.org/10.1096/fj.201500026R Rye KA; Barter PJ; Cochran BJ, 2015, 'Apolipoprotein A-I interactions with insulin secretion and production', Current Opinion in Lipidology, http://dx.doi.org/10.1097/MOL.0000000000000253 Cochran BJ; Bisoendial RJ; Hou L; Glaros EN; Rossy J; Thomas SR; Barter PJ; Rye KA, 2014, 'Apolipoprotein A-I increases insulin secretion and production from pancreatic β-cells via a G-protein-cAMPPKA-FoxO1-dependent mechanism', Arteriosclerosis, Thrombosis and Vascular Biology, vol. 34, no. 10, pp. 2261 - 2267, http://dx.doi.org/10.1161/ATVBAHA.114.304131 Lee JA; Cochran BJ; Lobov S; Ranson M, 2011, 'Forty years later and the role of plasminogen activator inhibitor type 2/SERPINB2 is still an enigma', Seminars in Thrombosis and Hemostasis, vol. 37, no. 4, pp. 395 - 407, http://dx.doi.org/10.1055/s-0031-1276589 Cochran BJ; Croucher DR; Lobov S; Saunders DN; Ranson M, 2011, 'Dependence on endocytic receptor binding via a minimal binding motif underlies the differential prognostic profiles of serpinE1 and serpinB2 in cancer', Journal of Biological Chemistry, vol. 286, no. 27, pp. 24467 - 24475, http://dx.doi.org/10.1074/jbc.M111.225706 Cochran BJ; Gunawardhana LP; Vine KL; Lee JA; Lobov S; Ranson M, 2009, 'The CD-loop of PAI-2 (SERPINB2) is redundant in the targeting, inhibition and clearance of cell surface uPA activity', BMC Biotechnology, vol. 9, http://dx.doi.org/10.1186/1472-6750-9-43