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研究领域

Gastrointestinal Diseases, Pharmacology, Neuroscience, Urology, Ageing

a) neurochemicals in human intestine: alterations in disease. b) neurochemicals in the human bladder: relevance to urinary incontinence. c) urothelium of the pig bladder as a model for human bladder studies.

近期论文

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Dai L; King DW; Perera DS; Lubowski DZ; Burcher E; Liu L, 2015, 'Inverse Expression of Prostaglandin E2-Related Enzymes Highlights Differences Between Diverticulitis and Inflammatory Bowel Disease', Digestive Diseases and Sciences, http://dx.doi.org/10.1007/s10620-014-3478-7 Cheng Y; Mansfield KJ; Allen W; Chess-Williams R; Burcher E; Moore KH, 2014, 'ATP during early bladder stretch is important for urgency in detrusor overactivity patients', BioMed Research International, vol. 2014, http://dx.doi.org/10.1155/2014/204604 Bahadory F; Moore KH; Liu L; Burcher E, 2013, 'Gene expression of muscarinic, tachykinin, and purinergic receptors in porcine bladder: Comparison with cultured cells', Frontiers in Pharmacology, vol. 4, no. NOV, pp. 1 - 7, http://dx.doi.org/10.3389/fphar.2013.00148 Cheng Y; Mansfield KJ; Allen W; Millard RJ; Burcher E; Moore KH, 2013, 'Correlation between cystometric volumes, ATP release, and pH in women with overactive bladder versus controls', Obstetrical and Gynecological Survey, vol. 68, no. 12, pp. 790 - 791, http://dx.doi.org/10.1097/01.ogx.0000441143.51421.c4 Cheng Y; Mansfield KJ; Allen W; Millard RJ; Burcher E; Moore KH, 2013, 'Correlation between cystometric volumes, ATP release, and pH in women with overactive bladder versus controls', Neurourology and Urodynamics, vol. 32, no. 7, pp. 969 - 973, http://dx.doi.org/10.1002/nau.22344 Dai L; Perera DS; King DW; Southwell BR; Burcher E; Liu L, 2012, 'Hemokinin-1 stimulates prostaglandin E 2 production in human colon through activation of cyclooxygenase-2 and inhibition of 15-hydroxyprostaglandin dehydrogenase', Journal of Pharmacology and Experimental Therapeutics, vol. 340, no. 1, pp. 27 - 36, http://dx.doi.org/10.1124/jpet.111.186155 Sadananda P; Kao FCL; Liu L; Mansfield KJ; Burcher E, 2012, 'Acid and stretch, but not capsaicin, are effective stimuli for ATP release in the porcine bladder mucosa: Are ASIC and TRPV1 receptors involved?', European Journal of Pharmacology, vol. 683, no. 1-3, pp. 252 - 259, http://dx.doi.org/10.1016/j.ejphar.2012.02.041 French M; Peck C; Liu L; Burcher E; Southwell BR, 2011, 'Hemokinin-immunoreactivity in immune cells in inflamed colon', Journal of Gastroenterology and Hepatology, vol. 26, pp. 21 - 21, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295157300053&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a Azriel Y; Liu L; Burcher E, 2011, 'Erratum: Complex actions of neurotensin in ascending and sigmoid colonic muscle: Involvement of enteric mediators (European Journal of Pharmacology (2010) 644 (195-202))', European Journal of Pharmacology, vol. 650, no. 2-3, pp. 708, http://dx.doi.org/10.1016/j.ejphar.2010.10.018 Liu L; Markus I; Saghire HE; Perera DS; King DW; Burcher E, 2011, 'Distinct differences in tachykinin gene expression in ulcerative colitis, Crohn's disease and diverticular disease: A role for hemokinin-1?', Neurogastroenterology and Motility, vol. 23, no. 5, http://dx.doi.org/10.1111/j.1365-2982.2011.01685.x Woodman JR; Mansfield KJ; Lazzaro VA; Lynch W; Burcher E; Moore KH, 2011, 'Immunocytochemical characterisation of cultures of human bladder mucosal cells', BMC Urology, vol. 11, http://dx.doi.org/10.1186/1471-2490-11-5 Cheng Y; Mansfield KJ; Sandow SL; Sadananda P; Burcher E; Moore KH, 2011, 'Porcine bladder urothelial, myofibroblast, and detrusor muscle cells: Characterization and ATP release', Frontiers in Pharmacology, vol. JUN, http://dx.doi.org/10.3389/fphar.2011.00027 Sandow SL; Sadananda P; Burcher E, 2010, 'INNERVATED MYOFIBROBLASTS IN THE URINARY BLADDER? FUNCTIONAL AND ULTRASTRUCTURAL EVIDENCE', International Urogynecology Journal and Pelvic Floor Dysfunction, vol. 21, pp. S97 - S98, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000281061800065&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a Harrington AM; Peck CJ; Liu L; Burcher E; Hutson JM; Southwell BR, 2010, 'Localization of muscarinic receptors M1R, M2R and M3R in the human colon', Neurogastroenterology and Motility, vol. 22, no. 9, http://dx.doi.org/10.1111/j.1365-2982.2009.01456.x Cheng Y; Mansfield KJ; Allen W; Walsh CA; Burcher E; Moore KH, 2010, 'Does Adenosine Triphosphate Released Into Voided Urodynamic Fluid Contribute to Urgency Signaling in Women With Bladder Dysfunction?', Journal of Urology, vol. 183, no. 3, pp. 1082 - 1086, http://dx.doi.org/10.1016/j.juro.2009.11.028 Mansfield KJ; Chandran JJ; Vaux KJ; Millard RJ; Christopoulos A; Mitchelson FJ; Burcher E, 2009, 'Comparison of receptor binding characteristics of commonly used muscarinic antagonists in human bladder detrusor and mucosa', Journal of Pharmacology and Experimental Therapeutics, vol. 328, no. 3, pp. 893 - 899, http://dx.doi.org/10.1124/jpet.108.145508 Liu L; Shang F; Morgan MJ; King DW; Lubowski DZ; Burcher E, 2009, 'Cyclooxygenase-dependent alterations in substance P-mediated contractility and tachykinin NK1 receptor expression in the colonic circular muscle of patients with slow transit constipation', Journal of Pharmacology and Experimental Therapeutics, vol. 329, no. 1, pp. 282 - 289, http://dx.doi.org/10.1124/jpet.108.148148 Sadananda P; Shang F; Liu L; Mansfield KJ; Burcher E, 2009, 'Release of ATP from rat urinary bladder mucosa: Role of acid, vanilloids and stretch', British Journal of Pharmacology, vol. 158, no. 7, pp. 1655 - 1662, http://dx.doi.org/10.1111/j.1476-5381.2009.00431.x Sadananda P; Chess-Williams R; Burcher E, 2008, 'Contractile properties of the pig bladder mucosa in response to neurokinin A: A role for myofibroblasts?', British Journal of Pharmacology, vol. 153, no. 7, pp. 1465 - 1473, http://dx.doi.org/10.1038/bjp.2008.29 Burcher E; Shang F; Warner FJ; Du Q; Lubowski DZ; King DW; Liu L, 2008, 'Tachykinin NK2 receptor and functional mechanisms in human colon: Changes with indomethacin and in diverticular disease and ulcerative colitis', Journal of Pharmacology and Experimental Therapeutics, vol. 324, no. 1, pp. 170 - 178, http://dx.doi.org/10.1124/jpet.107.130385

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