Boecking, Till - University of New South Wales

个人简介

Till trained in the physical sciences as a PhD student with Hans Coster and Kevin Barrow and as a postdoctoral associate with Justin Gooding and Mike Gal focusing on molecular self-assembly before heading to Boston to work on the endocytosis machinery with cell biologist Tom Kirchhausen. He now leads the Molecular Machines Group in the Single Molecule Science unit at UNSW. Awards: 2011-2014 ARC Future Fellowship 2011-2014 NHMRC Career Development Award (honorary) 2007–2010 HFSP Cross-Disciplinary Fellowship

近期论文

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Bonello TT; Janco M; Hook J; Byun A; Appaduray M; Dedova I; Hitchcock-DeGregori S; Hardeman EC; Stehn JR; Böcking T; Gunning PW, 2016, 'A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep19816 Al-Zyoud WA; Hynson RMG; Ganuelas LA; Coster ACF; Duff AP; Baker MAB; Stewart AG; Giannoulatou E; Ho JWK; Gaus K; Liu D; Lee LK; Böcking T, 2015, 'Binding of transcription factor GabR to DNA requires recognition of DNA shape at a location distinct from its cognate binding site', Nucleic Acids Research, vol. 44, no. 3, pp. 1411 - 1420, http://dx.doi.org/10.1093/nar/gkv1466 Polling S; Ormsby AR; Wood RJ; Lee K; Shoubridge C; Hughes JN; Thomas PQ; Griffin MDW; Hill AF; Bowden Q; Böcking T; Hatters DM, 2015, 'Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation', Nature Structural and Molecular Biology, http://dx.doi.org/10.1038/nsmb.3127 Pham S; Tabarin T; Garvey M; Pade C; Rossy J; Monaghan P; Hyatt A; Böcking T; Leis A; Gaus K; Mak J, 2015, 'Cryo-electron microscopy and single molecule fluorescent microscopy detect CD4 receptor induced HIV size expansion prior to cell entry', Virology, vol. 486, pp. 121 - 133, http://dx.doi.org/10.1016/j.virol.2015.09.006 Böcking T; Aguet F; Rapoport I; Banzhaf M; Yu A; Zeeh JC; Kirchhausen T, 2014, 'Key interactions for clathrin coat stability', Structure, vol. 22, no. 6, pp. 819 - 829, http://dx.doi.org/10.1016/j.str.2014.04.002 Ngalim SH; Magenau A; Zhu Y; Tønnesen L; Fairjones Z; Gooding JJ; Böcking T; Gaus K, 2013, 'Creating adhesive and soluble gradients for imaging cell migration with fluorescence microscopy.', Journal of Visualized Experiments, no. 74 Böcking T; Kilian KA; Reece PJ; Gaus K; Gal M; Gooding JJ, 2012, 'Biofunctionalization of free-standing porous silicon films for self-assembly of photonic devices', Soft Matter, vol. 8, no. 2, pp. 360 - 366, http://dx.doi.org/10.1039/c1sm06651j Böcking T; Aguet F; Harrison SC; Kirchhausen T, 2011, 'Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating', Nature Structural and Molecular Biology, vol. 18, no. 3, pp. 295 - 301, http://dx.doi.org/10.1038/nsmb.1985 Le Saux G; Magenau A; Böcking T; Gaus K; Gooding JJ, 2011, 'The relative importance of topography and RGD ligand density for endothelial cell adhesion', PLoS One, vol. 6, no. 7, http://dx.doi.org/10.1371/journal.pone.0021869 Le Saux G; Magenau A; Gunaratnam K; Kilian KA; Böcking T; Gooding JJ; Gaus K, 2011, 'Spacing of integrin ligands influences signal transduction in endothelial cells', Biophysical Journal, vol. 101, no. 4, pp. 764 - 773, http://dx.doi.org/10.1016/j.bpj.2011.06.064 Xing Y; Böcking T; Wolf M; Grigorieff N; Kirchhausen T; Harrison SC, 2010, 'Structure of clathrin coat with bound Hsc70 and auxilin: Mechanism of Hsc70-facilitated disassembly', The EMBO Journal, vol. 29, no. 3, pp. 655 - 665, http://dx.doi.org/10.1038/emboj.2009.383 Qiao H; Guan B; Böcking T; Gal M; Gooding JJ; Reece PJ, 2010, 'Optical properties of II-VI colloidal quantum dot doped porous silicon microcavities', Applied Physics Letters, vol. 96, no. 16, http://dx.doi.org/10.1063/1.3404183 Böcking T; Kilian KA; Reece PJ; Gaus K; Gal M; Gooding JJ, 2010, 'Substrate independent assembly of optical structures guided by biomolecular interactions', ACS Applied Materials and Interfaces, vol. 2, no. 11, pp. 3270 - 3275, http://dx.doi.org/10.1021/am1007084 Kilian KA; Böcking T; Gooding JJ, 2009, 'The importance of surface chemistry in mesoporous materials: Lessons from porous silicon biosensors', Chemical Communications, no. 6, pp. 630 - 640, http://dx.doi.org/10.1039/b815449j Kilian KA; Lai LMH; Magenau A; Cartland S; Bocking T; Girolamo ND; Gal M; Gaus K; Gooding JJ, 2009, 'Smart tissue culture: in situ monitoring of the activity of protease enzymes secreted from live cells using nanostructured photonic crystals', Nano Letters: a journal dedicated to nanoscience and nanotechnology, vol. 9, no. 5, pp. 2021 - 2025, http://dx.doi.org/10.1021/nl900283j Rapoport I; Boll W; Yu A; Böcking T; Kirchhausen T, 2008, 'A motif in the clathrin heavy chain required for the Hsc70/auxilin uncoating reaction', Molecular Biology of the Cell, vol. 19, no. 1, pp. 405 - 413, http://dx.doi.org/10.1091/mbc.E07-09-0870 Ciampi S; Bocking T; Kilian KA; Harper JB; Gooding JJ, 2008, 'Click chemistry in mesoporous materials: Functionalization of porous silicon rugate filters', Langmuir: the ACS journal of surfaces and colloids, vol. 24, no. 11, pp. 5888 - 5892, http://dx.doi.org/10.1021/la800435d Chou A; Böcking T; Liu R; Singh NK; Moran G; Gooding JJ, 2008, 'Effect of dialysis on the electrochemical properties of acid-oxidized single-walled carbon nanotubes', The Journal of Physical Chemistry Part C: Nanomaterials and Interfaces, vol. 112, no. 36, pp. 14131 - 14138, http://dx.doi.org/10.1021/jp7113785 Kilian KA; Böcking T; Gaus K; Gooding JJ, 2008, 'Introducing distinctly different chemical functionalities onto the internal and external surfaces of mesoporous materials', Angewandte Chemie International Edition, vol. 47, no. 14, pp. 2697 - 2699, http://dx.doi.org/10.1002/anie.200704784 Böcking T; Kilian KA; Gaus K; Gooding JJ, 2008, 'Modifying porous silicon with self-assembled monolayers for biomedical applications: The influence of surface coverage on stability and biomolecule coupling', Advanced Functional Materials, vol. 18, no. 23, pp. 3827 - 3833, http://dx.doi.org/10.1002/adfm.200800640