White, Peter - University of New South Wales - School of Biotechnology and Biomolecular Science

个人简介

2013-current: Professor, School of BABS 2008-2012: Associate Professor, School of BABS 2003-2007: Senior Lecturer, School of BABS, UNSW 1998-2002: Hepatitis Group Leader, Virology Division, Prince of Wales Hospital 1997-1998: NHMRC-funded Postdoctoral Research Fellow, Macquarie University 1996-1997: Royal Society Postdoctoral Research Fellow, Macquarie University

研究领域

Peter is a Professor in Microbiology and Molecular Biology. His current work focuses on molecular virology with a particular interests in antiviral agents, viral replication, viral recombination, viral evolution and identification of pandemic noroviruses. He has a breadth of experience in the development of novel molecular assay systems to investigate viral infections. He also has interests in antibiotic resistance in gram-negative bacteria and applied biotechnology. Following a BSc (Hons) in Biotechnology from King’s College London, University of London (1992), Peter completed a PhD at University College, London (1996) in molecular microbiology, where he identified and studied virulence proteins from bacterial pathogens. He commenced his postdoctoral research at Macquarie University in Sydney as a recipient of a Royal Society Postdoctoral Fellowship. He spent two years working on integrons and their role in antibiotic resistance in gram-negative bacteria, before moving to the Microbiology of Department at the Prince of Wales Hospital as Hepatitis Group Leader. From 1998 to 2003 he continued his work on drug resistance in bacteria and he began a major norovirus research program, supported by Professor Bill Rawlinson and staff at the Prince of Wales Hospital. In 2003 he took up an appointment at the University of New South Wales as a Senior Lecturer in Microbiology and Molecular Biology, where he continued to work on hepatitis C virus (HCV), norovirus and antibiotic resistance. Peter has supervised 9 PhD, one M.Sc student and 26 Honours students and he has 76 publications in the field of microbiology. He is the current President of the Australian Centre for Hepatitis Virology. Peter heads the Molecular Microbiology Laboratory in the School of BABS, located in state-of-the-art facilities. Research in this multi-disciplined group encompasses the themes of molecular virology, evolution, antivirals and biotechnology. Projects currently focuses on two viruses, norovirus and hepatitis C virus, but other projects involving dog viruses, bovine fat stem cells, microbiological reference standards and antiviral topical creams are also running.

近期论文

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Lim KL; Hewitt J; Sitabkhan A; Eden JS; Lun J; Levy A; Merif J; Smith D; Rawlinson WD; White PA, 2016, 'A multi-site study of norovirus molecular epidemiology in australia and New Zealand, 2013-2014', PLoS One, vol. 11, no. 4, http://dx.doi.org/10.1371/journal.pone.0145254 Urakova N; Netzler N; Kelly AG; Frese M; White PA; Strive T, 2016, 'Purification and biochemical characterisation of rabbit calicivirus RNA-dependent RNA polymerases and identification of non-nucleoside inhibitors', Viruses, vol. 8, no. 4, http://dx.doi.org/10.3390/v8040100 Eltahla AA; Luciani F; White PA; Lloyd AR; Bull RA, 2015, 'Inhibitors of the hepatitis C virus polymerase; mode of action and resistance', Viruses, vol. 7, no. 10, pp. 5206 - 5224, http://dx.doi.org/10.3390/v7102868 Koromyslova AD; White PA; Hansman GS, 2015, 'Treatment of norovirus particles with citrate', Virology, vol. 485, pp. 199 - 204, http://dx.doi.org/10.1016/j.virol.2015.07.009 De Graaf M; Van Beek J; Vennema H; Podkolzin AT; Hewitt J; Bucardo F; Templeton K; Mans J; Nordgren J; Reuter G; Lynch M; Rasmussen LD; Iritani N; Chan MC; Martella V; Ambert-Balay K; Vinjé J; White PA; Koopmans MP, 2015, 'Emergence of a novel GII.17 norovirus – end of the GII.4 era?', Eurosurveillance, vol. 20, no. 26, pp. 1 - 8 Castro TX; Cubel Garcia RDCN; Fumian TM; Costa EM; Mello R; White PA; Leite JPG, 2015, 'Detection and molecular characterization of caliciviruses (vesivirus and norovirus) in an outbreak of acute diarrhea in kittens from Brazil', The Veterinary Journal, http://dx.doi.org/10.1016/j.tvjl.2015.06.014 Alavi M; Spelman T; Matthews GV; Haber PS; Day C; van Beek I; Walsh N; Yeung B; Bruneau J; Petoumenos K; Dolan K; Kaldor JM; Dore GJ; Hellard M; Grebely J, 2015, 'Injecting risk behaviours following treatment for hepatitis C virus infection among people who inject drugs: The Australian Trial in Acute Hepatitis C', International Journal of Drug Policy, http://dx.doi.org/10.1016/j.drugpo.2015.05.003 Bretaña NA; Boelen L; Bull R; Teutsch S; White PA; Lloyd AR; Luciani F; HITS-p investigators, 2015, 'Transmission of Hepatitis C Virus among Prisoners, Australia, 2005-2012.', Emerging Infectious Diseases, vol. 21, no. 5, pp. 765 - 774, http://dx.doi.org/10.3201/eid2105.141832 Alhammad YMO; Maharajh S; Butcher R; Eden JS; White PA; Poumbourios P; Drummer HE, 2015, 'Longitudinal sequence and functional evolution within glycoprotein E2 in hepatitis C virus genotype 3a infection', PLoS One, vol. 10, no. 5, http://dx.doi.org/10.1371/journal.pone.0126397 Eltahla AA; Tay E; Douglas MW; White PA, 2014, 'Cross-genotypic examination of hepatitis c virus polymerase inhibitors reveals a novel mechanism of action for thumb binders', Antimicrobial Agents and Chemotherapy, vol. 58, no. 12, pp. 7215 - 7224, http://dx.doi.org/10.1128/AAC.03699-14 Hamblin SR; White PA; Tanaka MM, 2014, 'Viral niche construction alters hosts and ecosystems at multiple scales', Trends in Ecology and Evolution, vol. 29, no. 11, pp. 594 - 599, http://dx.doi.org/10.1016/j.tree.2014.08.005 White PA, 2014, 'Evolution of norovirus', Clinical Microbiology and Infection, vol. 20, no. 8, pp. 741 - 745, http://dx.doi.org/10.1111/1469-0691.12746 Hartfield M; Bull R; White PA; Lloyd A; Luciani F; Alizon S, 2014, 'Evidence that hepatitis C virus genome partly controls infection outcome', Evolutionary Applications: evolutionary approaches to environmental, biomedical and socio-economic issues, vol. 7, no. 5, pp. 533 - 547, http://dx.doi.org/10.1111/eva.12151 Eltahla AA; Lim KL; Eden JS; Kelly AG; Mackenzie JM; White PA, 2014, 'Nonnucleoside inhibitors of norovirus rna polymerase: Scaffolds for rational drug design', Antimicrobial Agents and Chemotherapy, vol. 58, no. 6, pp. 3115 - 3123, http://dx.doi.org/10.1128/AAC.02799-13 Eden JS; Hewitt J; Lim KL; Boni MF; Merif J; Greening G; Ratcliff RM; Holmes EC; Tanaka MM; Rawlinson WD; White PA, 2014, 'The emergence and evolution of the novel epidemic norovirus GII.4 variant Sydney 2012.', Virology, vol. 450-451, pp. 106 - 113, http://dx.doi.org/10.1016/j.virol.2013.12.005 van Beek J; Ambert-Balay K; Botteldoorn N; Eden JS; Fonager J; Hewitt J; Iritani N; Kroneman A; Vennema H; Vinjé J; White PA; Koopmans M; NoroNet, 2013, 'Indications for worldwide increased norovirus activity associated with emergence of a new variant of genotype II.4, late 2012.', Eurosurveillance, vol. 18, no. 1, pp. 8 - 9, http://www.ncbi.nlm.nih.gov/pubmed/23305715 Flynn JK; Dore GJ; Hellard M; Yeung B; Rawlinson WD; White PA; Kaldor JM; Lloyd AR; Ffrench RA, 2013, 'Maintenance of Th1 hepatitis C virus (HCV)-specific responses in individuals with acute HCV who achieve sustained virological clearance after treatment', Journal of Gastroenterology and Hepatology, vol. 28, no. 11, pp. 1770 - 1781, http://dx.doi.org/10.1111/jgh.12265 Lim KL; Eden J-S; Oon LLE; White PA, 2013, 'Molecular epidemiology of norovirus in Singapore, 2004-2011', Journal of Medical Virology, vol. 85, no. 10, pp. 1842 - 1851, http://dx.doi.org/10.1002/jmv.23669 Kroneman A; Vega E; Vennema H; Vinjé J; White PA; Hansman G; Green K; Martella V; Katayama K; Koopmans M, 2013, 'Proposal for a unified norovirus nomenclature and genotyping', Archives of Virology, vol. 158, no. 10, pp. 2059 - 2068, http://dx.doi.org/10.1007/s00705-013-1708-5 Sugden PB; Pham TNQ; Ratnarajah S; Cameron B; Bull R; White PA; Michalak TI; Lloyd AR, 2013, 'Rare occurrence of occult hepatitis C virus in apparently uninfected injecting drug users: a two-centre, masked, case-control study', Journal of Viral Hepatitis, vol. 20, no. 10, pp. 725 - 728, http://dx.doi.org/10.1111/jvh.12098