Crossley, Merlin - University of New South Wales - School of Biotechnology and Biomolecular Science

研究领域

The Role of Transcription Factors in Development and Disease; Molecular Genetics and Gene Regulation

近期论文

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Knights AJ; Yik JJ; Jusoh HM; Norton LJ; Funnell APW; Pearson RCM; Bell-Anderson KS; Crossley M; Quinlan KGR, 2016, 'Krüppel-like factor 3 (KLF3/BKLF) is required for widespread repression of the inflammatory modulator galectin-3 (Lgals3)', Journal of Biological Chemistry, vol. 291, no. 31, pp. 16048 - 16058, http://dx.doi.org/10.1074/jbc.M116.715748 Mak KS; Burdach J; Norton LJ; Pearson RCM; Crossley M; Funnell APW, 2016, 'Erratum to: Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor [Genome Biology, 15 (2014) R58]', Genome Biology: biology for the post-genomic era, vol. 17, no. 1, http://dx.doi.org/10.1186/s13059-016-0977-1 Berber S; Wood M; Llamosas E; Thaivalappil P; Lee K; Liao BM; Chew YL; Rhodes A; Yucel D; Crossley M; Nicholas HR, 2016, 'Homeodomain-Interacting Protein Kinase (HPK-1) regulates stress responses and ageing in C. elegans', Scientific Reports, vol. 6, http://dx.doi.org/10.1038/srep19582 Masuda T; Wang X; Maeda M; Canver MC; Sher F; Funnell APW; Fisher C; Suciu M; Martyn GE; Norton LJ; Zhu C; Kurita R; Nakamura Y; Xu J; Higgs DR; Crossley M; Bauer DE; Orkin SH; Kharchenko PV; Maeda T, 2016, 'Gene regulation: Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin', Science, vol. 351, no. 6270, pp. 285 - 289, http://dx.doi.org/10.1126/science.aad3312 Lim WF; Burdach J; Funnell APW; Pearson RCM; Quinlan KGR; Crossley M, 2015, 'Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain', Nucleic Acids Research, vol. 44, no. 7, pp. 3118 - 3130, http://dx.doi.org/10.1093/nar/gkv1380 Wienert B; Funnell APW; Norton LJ; Pearson RCM; Wilkinson-White LE; Lester K; Vadolas J; Porteus MH; Matthews JM; Quinlan KGR; Crossley M, 2015, 'Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin', Nature Communications, vol. 6, http://dx.doi.org/10.1038/ncomms8085 Dewi V; Kwok A; Lee S; Lee MM; Tan YM; Nicholas HR; Isono KI; Wienert B; Mak KS; Knights AJ; Quinlan KGR; Cordwell SJ; Funnell APW; Pearson RCM; Crossley M, 2015, 'Phosphorylation of krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomaininteracting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity', Journal of Biological Chemistry, vol. 290, no. 13, pp. 8591 - 8605, http://dx.doi.org/10.1074/jbc.M115.638338 Ballester B; Medina-Rivera A; Schmidt D; Gonzàlez-Porta M; Carlucci M; Chen X; Chessman K; Faure AJ; Funnell APW; Goncalves A; Kutter C; Lukk M; Menon S; McLaren WM; Stefflova K; Watt S; Weirauch MT; Crossley M; Marioni JC; Odom DT; Flicek P; Wilson MD, 2014, 'Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways', eLife, vol. 3, pp. e02626, http://dx.doi.org/10.7554/eLife.02626 Clifton MK; Westman BJ; Thong SY; O'Connell MR; Webster MW; Shepherd NE; Quinlan KG; Crossley M; Blobel GA; Mackay JP, 2014, 'The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins', PLoS One, vol. 9, no. 8, http://dx.doi.org/10.1371/journal.pone.0106011 Ballester B; Medina-Rivera A; Schmidt D; Gonzàlez-Porta M; Carlucci M; Chen X; Chessman K; Faure AJ; Funnell APW; Goncalves A; Kutter C; Lukk M; Menon S; McLaren WM; Stefflova K; Watt S; Weirauch MT; Crossley M; Marioni JC; Odom DT; Flicek P; Wilson MD, 2014, 'Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways', eLife, vol. 3, no. October2014, pp. 1 - 29, http://dx.doi.org/10.7554/eLife.02626 Reid A; Yücel D; Wood M; Llamosas E; Kant S; Crossley M; Nicholas H, 2014, 'The transcriptional repressor CTBP-1 functions in the nervous system of Caenorhabditis elegans to regulate lifespan', Experimental Gerontology, vol. 60, pp. 153 - 165, http://dx.doi.org/10.1016/j.exger.2014.09.022 Yücel D; Hoe M; Llamosas E; Kant S; Jamieson C; Nicholas HR; Young PA; Crossley M, 2014, 'SUMV-1 antagonizes the activity of synthetic multivulva genes in Caenorhabditis elegans', Developmental Biology, http://dx.doi.org/10.1016/j.ydbio.2014.05.018 Funnell APW; Vernimmen D; Lim WF; Mak KS; Wienert B; Martyn GE; Artuz CM; Burdach J; Quinlan KGR; Higgs DR; Whitelaw E; Pearson RCM; Crossley M, 2014, 'Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells', BMC Molecular Biology, vol. 15, http://dx.doi.org/10.1186/1471-2199-15-8 Mak KS; Burdach J; Norton LJ; Pearson RCM; Crossley M; Funnell APW, 2014, 'Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor', Genome Biology: biology for the post-genomic era, vol. 15, no. 4, http://dx.doi.org/10.1186/gb-2014-15-4-r58 Knights AJ; Funnell AP; Pearson RC; Crossley M; Bell-Anderson KS, 2014, 'Adipokines and insulin action: A sensitive issue.', Adipocyte, vol. 3, no. 2, pp. 88 - 96, http://dx.doi.org/10.4161/adip.27552 Burdach J; Funnell APW; Mak KS; Artuz CM; Wienert B; Lim WF; Tan LY; Pearson RCM; Crossley M, 2014, 'Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor', Nucleic Acids Research, vol. 42, no. 1, pp. 276 - 289, http://dx.doi.org/10.1093/nar/gkt895 Funnell APW; Crossley M, 2014, 'Hemophilia B Leyden and once mysterious cis-regulatory mutations', Trends in Genetics, vol. 30, no. 1, pp. 18 - 23, http://dx.doi.org/10.1016/j.tig.2013.09.007 Bell-Anderson KS; Funnell AP; Williams H; Jusoh HM; Scully T; Lim WF; Burdach JG; Mak KS; Knights AJ; Hoy AJ; Nicholas HR; Sainsbury A; Turner N; Pearson RC; Crossley M, 2013, 'Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/C1qdc2)', Diabetes, vol. 62, no. 8, pp. 2728 - 2737, http://dx.doi.org/10.2337/db12-1745 Berber S; Llamosas E; Thaivalappil P; Boag PR; Crossley M; Nicholas HR, 2013, 'Homeodomain interacting protein kinase (HPK-1) is required in the soma for robust germline proliferation in C. elegans', Developmental Dynamics, vol. 242, no. 11, pp. 1250 - 1261, http://dx.doi.org/10.1002/dvdy.24023 Mackay JP; Segal DJ; Crossley M, 2013, 'Is there a telltale RH fingerprint in zinc fingers that recognizes methylated CpG dinucleotides?', Trends in Biochemical Sciences, vol. 38, no. 9, pp. 421 - 422, http://dx.doi.org/10.1016/j.tibs.2013.06.005