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刘泓宇,博士,副教授,硕士生导师,瑞典卡罗林斯卡医学院博士后,先后主持广东省自然科学基金、中国-比利时国际合作项目及湛江市科技计划攻关项目多项,作为主要完成人参与国家自然基金项目3项、国家重大基础研究课题973项目、农业部科技跨越计划、行业公益项目及天津市农业科技成果转化与推广项目等10余项重大课题;在国内外知名刊物上发表学术论文40余篇,其中SCI收录论文30余篇(第一及通讯作者20篇);获山东省科学技术奖三等奖及湛江市科学技术奖三等奖各1项。目前从事水产动物营养和环境生理学及分子生物学的教学和科研工作,主讲本科生《细胞生物学》及研究生《分子营养学》课程,主要运用生物信息学、营养学、免疫组织化学及分子生物学技术研究水产经济动物抗逆应激基因和生长代谢基因的表达与调控。 一、学习/工作经历 1996 - 2000, 陕西师范大学,生物科学,学士 2000 - 2003,广东省深圳市铁路中学,教师 2003 - 2006, 中国海洋大学,水产养殖,硕士 2006 - 2009, 中国海洋大学,水产养殖,博士 2009 - 2014, 广东海洋大学水产学院,助教、讲师 2014 – 今, 广东海洋大学水产学院,副教授 2014 - 2015, 瑞典卡罗林斯卡医学院,博士后 二、主要科研项目 1、广东省自然科学基金,2018A030313154,珍珠龙胆石斑鱼GLUT4分子特性及葡萄糖耐受调控机制研究,2018/10-2021/10,10万元,在研,主持。 2、广东省自然科学基金,S2013010016511,军曹鱼葡萄糖转运蛋白及血糖内稳态调控机制研究,2013/10-2015/10,5万元,结题,主持。 3、国家自然科学基金,31772864,不同食性鱼类4型葡萄糖转运蛋白及其介导PI3K信号通路的糖耐受调控机制比较研究2018.01.01-2021.12.31,75万,在研,主要参与。 4、国家自然科学基金,31272673,不同食性热带海洋鱼类葡萄糖耐量及外周糖代谢调控与利用机制研究,2013.01.01-2016.12.01,85万,结题,主要参与。 5、国家自然科学基金,30871928,饲料或水体中添加K离子对凡纳滨对虾低盐环境下氨代谢、渗透调节和免疫力的影响,2009.01.01-2011.12.01,32万,结题,主要参与。 三、科研奖励 [1] 潘鲁青、王恒台、苗晶晶、张大科、刘泓宇、杨慧赞,盐碱地对虾养殖环境生理学及开发应用,山东省科学技术三等奖,2007,证书号:JB2006-3-43-3-5 [2] 周歧存、迟淑艳、杨奇慧、董晓慧、刘泓宇,台湾东风螺营养生理的研究及配合饲料的开发,湛江市科学技术奖励三等奖,2011,证书号:2011-3-31-R04-212 四、教学奖励 1、广东海洋大学中青年教师观摩授课竞赛三等奖(2012年) 2、广东海洋大学中青年教师观摩授课竞赛二等奖(2016年) 五、指导研究生获奖情况 李锐鑫(2016级),第五届“环北部湾高校研究生海洋学术论坛”论文一等奖 李锐鑫(2016级),第六届“环北部湾高校研究生海洋学术论坛”论文一等奖 殷彬(2016级),2018年广东水产学会首届青年科技论坛论文三等奖 李锐鑫(2016级),国家奖学金(2018年) 殷彬(2016级),国家奖学金(2018年) 六、荣誉称号 广东海洋大学先进个人(2012年) 广东海洋大学工会积极分子(2017年) 广东海洋大学优秀班主任(2018年)

研究领域

水产动物营养和环境生理学及分子生物学的教学和科研

近期论文

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[1] Liu H.Y., Pan L.Q., Lv F., 2008. Effects of salinity on biogenic amines, haemolymph osmotic pressure and activity of gills Na+-K+-ATPase in the Charybdis japonica (crustacea, Decapoda). J World Aquaculture Society. 39(6), 812~820. [2] Liu H.Y., Pan L.Q., Zheng D.B., 2008. Injection of biogenic amines modulates osmoregulation of Litopenaeus vannamei: Response of hemolymph osmotic pressure, ion concentration and osmolality effectors. Comp Biochem Physiol, PartA.151,191~197. [3] Liu H.Y., Pan L.Q., Zheng D.B., 2008. Effects of salinity on hemolymph osmotic pressure, sodium concentration and Na+-K+-ATPase activity of gills in the Chinese crab Eriocheir sinensis. J Ocean University of China, 6(4), 193~199. [4] Liu H.Y., Pan L.Q., Zheng D.B., 2009. Effects of biogenic amines injection on expression of gill related ion transpoter mRNA and α–subunit protein in Litopenaeus vannamei. Comp Biochem Physiol., Part A.154 (1), 29~36. [5] Hong-yu Liu, Wu-wei Sun, Bei-ping Tan, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang., 2012. Molecular cloning and expression of hepatopancreas glutamine synthetase in the Pacific white shrimp, Litopenaeus vannamei, induced by acute hypo-osmotic stress. Aquaculture 362–363:80–87. [6] Hong-yu Liu, Jin-fang Yang, Bei-ping Tan, Yingbo Lin, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang., 2014. Effects of dietary potassium on growth, nitrogen metabolism, osmoregulation and immunity in the Pacific white shrimp (Litopenaeus vannamei) reared in low salinity seawater. J Ocean University of China, 13 (2): 311-320. [7] Hongyu Liu, Xinjie Zhang, Beiping Tan*, Yingbo Lin, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang, 2014, Effect of various Na/K ratios in low salinity well water on growth performance and physiological response of Pacific white shrimp, Litopenaeus vannamei. Chinese Journal of Oceanology and Limnology, 32(5):991-999. [8] Hongyu Liu, Zheng Li, Beiping Tan*, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang, 2014, Isolation of a putative probiotic strain S12 and its effect on growth performance, non-specific immunity and disease-resistance of white shrimp, Litopenaeus vannamei. Fish & Shellfish Immunology, 41(2):300-307. [9] Hongyu Liu, Beiping Tan*, Jinfang Yang, Yingbo Lin, Shu-yan Chi, Xiao-hui Dong, Qi-hui Yang, 2016, Effects of aqueous Na/K and dietary K on growth and physiological characters of the Pacific white shrimp, Litopenaeus vannamei, reared in low-salt well water. Aquaculture Research, 47(2): 540-553. [10] Hong-yu Liu, Wu-wei Sun, Xiao-hui Dong, Shu-yan Chi, Qi-hui Yang, Yuan-you Li, Bei-ping Tan. 2016. Profiling of Up-Regulated Genes Response to Acute Hypo-Osmotic Stress in Hepatopancreas and Gill of the Pacific White Shrimps (Litopenaeus vannamei). International Journal of Biology. 8(2): 43-57 [11] Liu H.Y., Dong, X., Chi, S., Yang, Q., Zhang, S., Chen, L., & Tan, B. (2017). Molecular cloning of glucose transporter 1 in grouper Epinephelus coioides and effects of an acute hyperglycemia stress on its expression and glucose tolerance. Fish physiology and biochemistry, 43(1), 103-114. [12] Liu H.Y., Tan, B., Yang, J., Chi, S., Dong, X., & Yang, Q. (2016). Effects of aqueous Na/K and dietary K on growth and physiological characters of the Pacific white shrimp, L itopenaeus vannamei, reared in low‐salt well water. Aquaculture research, 47(2), 540-553. [13] Li, R., Liu H.Y(共同第一)., Dong, X., Chi, S., Yang, Q., Zhang, S., & Tan, B. (2018). Molecular characterization and expression analysis of glucose transporter 1 and hepatic glycolytic enzymes activities from herbivorous fish Ctenopharyngodon idellus in respond to a glucose load after the adaptation to dietary carbohydrate levels. Aquaculture, 492, 290-299. [14] Yin, B., Liu H.Y.(共同第一)., Tan, B., Dong, X., Chi, S., Yang, Q., ... & Chen, L. (2018). Cottonseed protein concentrate (CPC) suppresses immune function in different intestinal segments of hybrid grouper♀ Epinephelus fuscoguttatus×♂Epinephelus lanceolatu via TLR-2/MyD88 signaling pathways. Fish & shellfish immunology, 81, 318-328. [15] Liu, H.Y., Chen, Q., Tan, B. P., Dong, X. H., Chi, S. Y., Yang, Q. H., ... & Chen, L. Q. (2018). Effects of dietary carbohydrate levels on growth, glucose tolerance, glucose homeostasis and GLUT4 gene expression in Tilapia nilotica. Aquaculture Research, 49(12), 3735-3745. [16] Li, R. X., Liu, H. Y(*通讯)., Chen, Q., Tan, B. P., Dong, X. H., Chi, S. Y., ... & Chen, L. Q. (2018). Glucose tolerance of grass carp Ctenopharyngodon idellus after a long‐term adaptation to carbohydrate‐to‐lipid ratio diets. Aquaculture Research, 49(12), 3881-3888. [17] Li, R. X., Liu, H. Y(*通讯)., Li, S. Y., Tan, B. P., Dong, X. H., Chi, S. Y., ... & Chen, L. Q. (2019). Nutritional regulation of gene expression and enzyme activity of phosphoenolpyruvate carboxykinase in the hepatic gluconeogenesis pathway in golden pompano (Trachinotus ovatus). Aquaculture Research, 50(2), 634-643 [18] Li, R., Chen, Q., Liu H.Y(*通讯)., Tan, B., Dong, X., Chi, S., ... & Zhang, S. (2019). Molecular characterization and expression analysis of glucose transporter 4 from Trachinotus ovatus, Rachycentron canadums and Oreochromis niloticus in response to different dietary carbohydrate-to-lipid ratios. Aquaculture, 501, 430-440 [19] Li, R., Liu H.Y(*通讯)., Li, S., Tan, B., Dong, X., Chi, S., Yang, Q., Zhang, S., (2019). Nutritional regulation of pyruvate kinase and phosphoenolpyruvate carboxykinase at the enzymatic and molecular levels in cobia Rachycentron canadum. Fish Physiology and biochemistry. Accepted, In press [20] Zhang, W., Liu, K., Tan, B., Liu H.Y(*通讯), Dong, X., Yang, Q., ... & Wang, H. (2019). Transcriptome, enzyme activity and histopathology analysis reveal the effects of dietary carbohydrate on glycometabolism in juvenile largemouth bass, Micropterus salmoides. Aquaculture. Accepted, In press [21] 刘泓宇, 张新节,谭北平,董晓慧, 迟淑艳、杨奇慧.饲料钾水平对低盐井水养殖凡纳滨对虾生长及生理特性的影响, 中国水产科学, 2014. 21(2): 321-329. [22] 刘泓宇, 谭北平,董晓慧, 迟淑艳、杨奇慧.低盐胁迫下凡纳滨对虾鳃丝抑制性消减杂交cDNA文库构建及差异EST分析. 海洋湖沼通报, 2014. (1): 56-66. [23] 刘泓宇, 毛义波, 谭北平, 等. 饲料糖水平对不同食性鱼类生长及葡萄糖耐受能力的影响[J]. 水产学报, 2015, 39(12): 1852-1862.

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