Kumar, Naresh - University of New South Wales

个人简介

PhD in Organic Chemistry from Wollongong University, 1983; Postdoctoral Research Fellow in Organic Chemistry, University of New South Wales, 1983 - 1985; Professional Officer, Organic Chemistry, UNSW 1985 - 1995; Project Scientist 1995 - 2003; Lecturer 2003 - 2008; Associate Professor 2008 - 2012; Professor 2013 - present.

研究领域

Natural products chemistry. Development of new synthetic methodologies for the preparation of biologically important natural products and their analogues. Novel antimicrobial biomaterials. Heterocyclic chemistry. Medicinal chemistry. Design and synthesis of quorum-sensing inhibitors.

近期论文

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Zhang R, Iskander G, da Dilva P, Chan D, Vignevich V, Nguyen V, Bhadbhade M, Black D, Kumar N, Synthesis of new aryl substituted furan-2(5H)-ones using the Suzuki-Miyaura reaction, Tetrahedron, 2011, 67, 3010-3016. Cheah WC,Wood K, Black DStC, and Kumar N, Facile ring-opening of N-acylisatins for the development of novel peptidomimetics. Tetrahedron, 2011, 67, 7603-7610. Devakaram R, Black DStC, Andrews KT, Fisher GM, Davis RA, Kumar N, Synthesis and antimalarial evaluation of novel benzopyrano[4,3-b]benzopyran derivatives. Bioorganic & Medicinal Chemistry, 2011,19, 5199-5206. Chen, R., Willcox M. D. P., Cole, N., Ho, K. K. K., Rasul, R., Denman, J. A., and Kumar, N., (2012) Characterization of chemoselective surface attachment of the cationic peptide melimine and its effects on antimicrobial activity. Acta Biomaterialia, 2012, 8, 4371-4379. Suryanti, V., Bhadbhade, M., Bishop, R., Black, D. StC., and Kumar, N. Self-assembly of alkyl N-acetylglyoxylic amides of varying chain lengths. CrystEngComm. 2012, 14, 7345-7354. Gardner, C. R., Cheung, B. B., Koach, J., Black, D. StC., Marshall, G. M., and Kumar, N. Synthesis of retinoid enhancers based on 2-aminobenzothiazoles for anti-cancer therapy. Bioorganic & Medicinal Chemistry, 2012, 20, 6877-6884. Ho K, Cole N, Chen R, Willcox MDP, Rice S, Kumar, N. Immobilisation of antibacterial dihydropyrrol-2-ones onto functional polymer supports to prevent bacterial infections in vivo, Antimicrobial Agents and Chemotherapy, 2012, 56, 1138-1141. Kutty, S. K., Barraud, N., Pham, A., Iskander, G., Rice, S. A., Black, D., StC.; Kumar, N. Design, Synthesis, and Evaluation of Fimbrolide-Nitric Oxide Donor Hybrids as Antimicrobial Agents, Journal of Medicinal Chemistry, 2013, 56, 9517-9529. Eugene MH, Pasqueir E, Iskander G, Black DStC, and Kumar N, Synthesis of novel isoflavene-propranolol hybrids as anti-tumor agents, Bioorganic &. Medicinal Chemistry, 2013, 21,1652-1660 Ho, K. K. K., Chen, R., Willcox, M. D. P., Rice, S. A., Cole, N, Iskander, G., Kumar, N. (2014) Quorum sensing inhibitory activities of surface immobilized antibacterial dihydropyrrolones via click chemistry, Biomaterials, 2014, 35, 2336-2345. Mielczarek, M., Devakaram, R. V., Ma, C., Yang, X., Kandemir, H., Purwono, B., Black, D. StC., Griffith, R., Lewis, P. J., Kumar, N., Synthesis and biological activity of novel bis-indole inhibitors of bacterial transcription initiation complex formation, Organic & Biomolecular Chemistry, 2014, 12, 2882-2882. Kutty, SK, Barraud N, Ho, KKK, Iskander GM, Griffith R, Rice S, Bhadbhade M, Willcox M, Black DStC, Kumar N., Hybrids of acylated homoserine lactone and nitric oxide donors as inhibitors of quorum sensing and virulence factors in Pseudomonas aeruginosa, Organic & Biomolecular Chemistry, 2015, 13, 9850-9861. Ho, K. K., Kutty, S., Chan, D., Chen, R., Willcox, M., Kumar, N., (2015) Development of Fimbrolides, Halogenated Furanones and their Analogues as Antimicrobial Agents, In E. Ivanova and R. Crawford (Eds): Antibacterial Surface Design, Springer International, 149-170. Hong, K, Ball G, Black DStC, Kumar, N., The Mosaic of Rotterlin, J. Org. Chem, 2015, 80, 10668-10674. Chen R, Willcox MDP, Ho KKK, Smyth D, Kumar N., Antimicrobial peptide melimine coating for titanium and its in vivo antibacterial activity in rodent subcutaneous infection models. Biomaterials, 2016, 85, 142-151. Nizalapur S, Kimyon O, Biswas NN, Gardner CR, Griffith R, Rice S, Manefield M, Willcox M, Black DStC, Kumar N., Design, synthesis and evaluation of N-arylglyoxylamides derivatives as structurally novel bacterial quorum sensing inhibitors, Organic & Biomolecular Chemistry, 2016, 14, 680-693.