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个人简介

教育经历 2006.9 2012.9 大连理工大学 生物化工 博士 2002.9 2006.7 辽宁大学 生物技术 学士 1999.9 2002.7 大连市第一高中 工作经历 2014.12 至今 大连理工大学 讲师 2012.7 2014.12 大连理工大学 博士后

研究领域

肿瘤分子生物学 周期节律与肿瘤发生发展机制

近期论文

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Chen Huan,Wang Miao,Wu Huijian,Xu Zhaowei,Li Xiahui,Yang Yangyang,Li Bowen,Li Yanan,Xia Kangkai,Wang Jian,Li Shujing.α-catenin SUMOylation increases IκBα stability and inhibits breast cancer progression[J],Oncogenesis,2018,7(3):28 Jia Zhaojun,Wu Huijian,Wang Miao,Li Shujing,Li Xiahui,Bai Xiao-Yan,Xu Zhaowei,Yang Yangyang,Li Bowen,Li Yanan.U-box ubiquitin ligase PPIL2 suppresses breast cancer invasion and metastasis by altering cell mo...[J],Cell death & disease,2018,9(2):63 Chen, Huan,Wang, Miao,Wu, Huijian,Xu, Zhaowei,Li, Xiahui,Yang, Yangyang,Li, Bowen,Li, Yanan,Xia, Kangkai,Wang, Jian,Li, Shujing.alpha-catenin SUMOylation increases IkappaBalpha stability and inhibits breast cancer progression...[J],Oncogenesis,2018,7(3) 李淑晶.α-catenin SUMOylation increases IκBαstability and inhibits breast cancer progression[J],Oncogenesis,2018 Bai, Xiao-Yan,Chen, Huan,Wu, Huijian,Li, Shujing,Wang, Miao,Li, Xiahui,Yang, Yangyang,Xu, Zhaowei,Li, Bowen,Li, Yanan,Xia, Kangkai.Kruppel-like factor 9 down-regulates matrix metalloproteinase 9 transcription and suppresses hu...[J],CANCER LETTERS,2018,412(412):224-235 Xu, Zhaowei,Wu, Huijian,Yang, Yangyang,Li, Bowen,Li, Yanan,Xia, Kangkai,Yang, Yuxi,Li, Xiahui,Wang, Miao,Li, Shujing.Checkpoint suppressor 1 suppresses transcriptional activity of ERalpha and breast cancer cell pro...[J],Cell death & disease,2018,9(5):559 李淑晶.Checkpoint suppressor 1 suppresses transcriptional activity of ERα and breastcancer cell prolife...[J],Cell death & disease,2018 Wang, Miao,Chen, Huan,Wu, Huijian,Li, Shujing,Xu, Zhaowei,Li, Xiahui,Yang, Yangyang,Li, Bowen,Li, Yanan,Guo, Jing.SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor...[J],ONCOTARGET,2017,8(52):89692-89706 李霞辉,李淑晶,伍会健.近日节律对乳腺癌他莫昔芬耐药的影响[J],生命的化学,2017,37(3):313-318 Li, Shujing,Wang, Miao,Qu, Xinjian,Xu, Zhaowei,Yang, Yangyang,Su, Qiming,Wu, Huijian.SUMOylation of PES1 upregulates its stability and function via inhibiting its ubiquitination[J],ONCOTARGET,2016,7(31):50507-50519 Jiang, Xiao,Zhang, Mei,Bai, Xiao-Yan,Li, Shujing,Wu, Huijian.Association between 17q25.3-rs6465657 polymorphism and prostate cancer susceptibility: a meta-a...[J],ONCOTARGETS AND THERAPY,2016,9:4491-4503 Ao, Xiang,Li, Shujing,Xu, Zhaowei,Yang, Yangyang,Chen, Min,Jiang, Xiao,Wu, Huijian.Sumoylation of TCF21 downregulates the transcriptional activity of estrogen receptor-alpha[J],ONCOTARGET,2016,7(18):26220-26234 Bi, H.,Yang, Y.,Wu, H.,Li, S.,Qu, X.,Wang, M.,Bai, X.,Xu, Z.,Ao, X.,Jia, Z.,Jiang, X..DEC1 regulates breast cancer cell proliferation by stabilizing cyclin E protein and delays the ...[J],CELL DEATH & DISEASE,2015,6(9):e1891 Bai, Xiao-Yan,Li, Shujing,Wang, Miao,Qu, Xinjian,Hu, Gaolei,Xu, Zhaowei,Chen, Min,He, Guo-Wei,Wu, Huijian.Association of Monocyte Chemoattractant Protein-1 (MCP-1)-2518A > G Polymorphism with Susceptib...[J],ANNALS OF HUMAN GENETICS,2015,79(3):173-187 Zhao, F.,Wang, M.,Li, S.,Bai, X.,Bi, H.,Liu, Y.,Ao, X.,Jia, Z.,Wu, H..DACH1 inhibits SNAI1-mediated epithelial-mesenchymal transition and represses breast carcinoma ...[J],ONCOGENESIS,2015,4(3):e143 Cui, Xiaoneng,Lou, Zhangrong,Li, Shujing,Wu, Huijian,Han, Ke-li,Zhao, Jianzhang.Switching of the Triplet Excited State of Rhodamine/Naphthaleneimide Dyads: An Experimental and...[J],JOURNAL OF ORGANIC CHEMISTRY,2015,80(1):568-581 王淼,李淑晶,伍会健.跨校区网络同步教学课程模式探索 细胞生物学课程改革[J],中国细胞生物学学报,2015,37(5):715-719 杨杨杨,李淑晶,伍会健.F-box蛋白家族在肿瘤发生中的作用[J],中国细胞生物学学报,2015,37(8):1180-1186 李淑晶.Association of Monocyte Chemoattractant Protein-1(MCP-1)-2518AG Polymorphism with Susceptibility ...[J],Annals of Human Genetics,2015,79(3):137-187 Zhao, Jianzhang,Huang, Ling,Cui, Xiaoneng,Li, Shujing,Wu, Huijian.Maximizing the thiol-activated photodynamic and fluorescence imaging functionalities of therano...[J],JOURNAL OF MATERIALS CHEMISTRY B,2015,3(47):9194-9211 陈敏,李淑晶,伍会健.泛素化与SUMO化对DNA损伤应答的调控作用简[J],生命的化学,2015,35(6):801-806 Bi, Hailian,Li, Shujing,Wang, Miao,Jia, Zhaojun,Chang, Alan K.,Pang, Pengsha,Wu, Huijian.SUMOylation of GPS2 protein regulates its transcription-suppressing function[J],MOLECULAR BIOLOGY OF THE CELL,2014,25(16):2499-2508 Xiao, Liyun,Li, Shujing,Wang, Miao,Xing, Xinrong,Wu, Huijian,Chang, Alan K.,Zang, Ming-Xi,Bi, Hailian.Induction of the CLOCK Gene by E2-ER alpha Signaling Promotes the Proliferation of Breast Cance...[J],PLOS ONE,2014,9(5):e95878 Li N.,Song Y.,Yu W.,Ma X.,Zhang Y.,Liu Y.,Xiu Z.,Tan M.,Li S.,Guo X.,Wang Y.,Chen L.,Lv G..Improved islet purity by the hypertonic-hypotonic method[J],International Journal of Artificial Organs,2014,37(6):477-485 Li, S.,Chang, A. K.,Yang, C.,Zhao, F.,Bi, H.,Liu, Y.,Xiao, L.,Wu, H.,Wang, M.,Ao, X..CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity ...[J],ONCOGENE,2013,32(41):4883-4891 Li, Shujing,Ao, Xiang,Wu, Huijian.The role of circadian rhythm in breast cancer[J],CHINESE JOURNAL OF CANCER RESEARCH,2013,25(4):442-450 Wang, Miao,Zhao, Feng,Pan, Hongming,Wu, Huijian,Li, Shujing,Chang, Alan K.,Jia, Zhaojun,Chen, Yixuan,Xu, Feihong.AIB1 Cooperates with ER alpha to Promote Epithelial Mesenchymal Transition in Breast Cancer thr...[J],PLOS ONE,2013,8(6):e65556 Yang, Chunhua,Li, Shen,Wu, Huijian,Li, Shujing,Wang, Miao,Chang, Alan K.,Liu, Ying,Zhao, Feng,Xiao, Liyun,Han, Lin,Wang, Dao.PTEN suppresses the oncogenic function of AIB1 through decreasing its protein stability via mec...[J],MOLECULAR CANCER,2013,12(1):21 Li, Shujing,Liu, Ying,Ao, Xiang,Pang, Pengsha,Xing, Xinrong,Chang, Alan K.,Xiao, Liyun,Zhang, Yuanyuan,Wu, Huijian,Yang, Chunhua,Hong, Yongde,Bi, Hailian,Zhao, Feng.The transcriptional activity of co-activator AIB1 is regulated by the SUMO E3 Ligase PIAS1[J],BIOLOGY OF THE CELL,2012,104(5):287-296 Hong, Yongde,Wu, Huijian,Xing, Xinrong,Li, Shujing,Bi, Hailian,Yang, Chunhua,Zhao, Feng,Liu, Ying,Ao, Xiang,Chang, Alan K..SUMOylation of DEC1 Protein Regulates Its Transcriptional Activity and Enhances Its Stability[J],PLOS ONE,2011,6(8):e23046 李淑晶,毕海连,伍会健.泛素连接酶APC/C和SCF复合物与肿瘤的关系[J],北京大学学报(医学版),2010,42(2):243-封3 敖翔,李淑晶,伍会健.周期节律与肿瘤关系的分子机理[J],中国生物化学与分子生物学报,2010,26(11):998-1002 李淑晶,刘文栋,伍会健.二恶英对雌激素受体的干扰作用[J],生命科学,2008,20(5):764-767 杨春华,李淑晶,伍会健.PTEN对ERα转录活性的调节[A],2008,1 李淑晶,程智逵,伍会健.SUMO在转录中的抑制作用[J],中国生物化学与分子生物学报,2007,23(7):525-530

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