冯延宾 - 大连理工大学 - 生物工程学院

个人简介

教育经历 2009.9 2014.6 南开大学生物化学与分子生物学博士 2005.9 2009.6 南开大学生物技术学士工作经历 2019.7 至今大连理工大学生物工程学院副教授 2018.6 2019.6 中国科学院大连化学物理研究所副研究员 2014.6 2018.6 中国科学院大连化学物理研究所助理研究员

研究领域

以蛋白质结构、进化和再设计为核心，建立新型蛋白质标记技术，如蛋白质荧光标记、蛋白质配体标记技术，进而研究蛋白质相互作用。结合结构生物学，细胞生物学，分析化学及酶催化动力学技术与方法，尤其通过蛋白-蛋白/小分子相互作用，研究新型生物能源合成途径关键酶的催化机制及理性设计改造。通过多酶体系构建与生物合成途径重构等方法，建立生物医药合成策略及目标物质定向生物合成

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Wang Q(#), Feng Y(#), Lu Y, Xin Y, Shen C, Wei L, Liu Y, Lv N, Du X, Zhu W, Jeong B, Xue S, Xu J Manipulating fatty-acid profile at unit chain length resolution in the model industrial oleaginous microalgae Nannochloropsis. Metabolic Engineering 2021; 66; 157-162 Liu Y(#), Feng Y(#), Wang L, Guo X, Liu W, Li Q, Wang X, Xue S, Zhao Z. Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor. ACS Catalysis 2019; 9(3); 1883-1887 Feng Y, Wang Y, Chu H, Fan Y, Cao X, Liu Y, Li G, Xue S. Stereoselective catalysis controlled by a native leucine or variant isoleucine wing-gatekeeper in 2-haloacid dehalogenase. Febs Lett 2019; 593(3); 308-318 Feng Y, Zhang Y, Ding W, Wu P, Cao X, Xue S. Expanding of Phospholipid:Diacylglycerol AcylTransferase from Saccharomyces cerevisiae as Multifunctional Biocatalyst With Broad Acyl Donor/Accpetor Selectivity. Appl. Biochem. Biotechnol. 2019;188(3):824-835 Ji F(#), Feng Y(#), Li M, Long F, Yang Y, Wang T, Wang J, Bao Y, Xue S. Structure and catalytic mechanism insight into the acetolactate decarboxylase from Enterobacter aerogenes. Enzyme Microb Technol, 2019 Feng Y, Zhang Y, Wang Y, Liu J, Liu Y, Cao X, Xue S. Tuning of acyl-ACP thioesterase activity directed for tailored fatty acid synthesis. Appl Microbiol Biotechnol 2018;102(7):3173-3182 Ji F(#), Feng Y(#), Li M, Yang Y, Wang T, Wang J, Bao Y, Xue S. Studies on structure-function relationships of acetolactate decarboxylase Enterobacter cloacae. RSC Adv. 2018(8):39066-39073 Zhang Y(#), Feng Y(#), Xin Y, Liu X. SGIP1 dimerizes via intermolecular disulfide bond in muHD domain during cellular endocytosis. Biochem Biophys Res Commun 2018;505(1):99-105 Feng Y, Wang Y, Liu J, Liu Y, Cao X, Xue S. Structural Insight into Acyl-ACP Thioesterase toward Substrate Specificity Design. ACS Chemical biology 2017;12(11):2830-2836 Liu Y(#), Feng Y(#), Cao X, Li X, Xue S. Structure-directed construction of a high-performance version of the enzyme FabG from the photosynthetic microorganism Synechocystis sp. PCC 6803. Febs Lett 2015; 589:3052-3057 Feng Y, Yu W, Li X, Lin S, Zhou Y, Hu J, Liu X. Structural insight into Golgi membrane stacking by GRASP65 and GRASP55 proteins. J Biol Chem 2013; 288(39):28418-28427