Kuchta, Robert - University of Colorado - Chemistry and Biochemistry

个人简介

Ph.D.: Brandeis University, 1986 Postdoctoral Fellow: Pennsylvania State University, 1987-88

研究领域

Environmental Chemistry Bioanalytical Chemistry Nucleic Acids

近期论文

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Steet, R. A., Melan?on, P., and Kuchta, R. D. (2000) "3'-Azidothymidine Potently Inhibits the Biosynthesis of Highly Branched N-linked Oligosaccharides and Poly-N-acetyllactosamine Chains in Cells" Journal of Biological Chemistry, 275, 26812-26820. Richardson, F. C., Kuchta, R. D., Mazurkiewicz, A. & Richardson, K. A. (2000) "Polymerization of 2’-Fluoro- and 2’-O-Methyl-dNTPs by Human DNA Primase, Polymerase alpha and Polymerase gamma" Biochemical Pharmacology, 59, 1045-1052. Steet, R., Alizebeh, M., Melan?on, P., and Kuchta, R. D. (1999) "3'-Azido-3'-deoxythymidine Inhibits both the Synthesis and Shedding of Gangliosides by Melanoma Cells" Glycoconjugate Journal, 16, 237-245. Zerbe, L.K., Goodman, M. F., Efrati, E., Kuchta, R. D. (1999) "Abasic Template Lesions Are Strong Chain Terminators for DNA Primase but not for DNA Polymerase alpha During the Synthesis of New DNA Strands" Biochemistry, 38, 12908-12914. Arezi, B., Kirk, B. W., Copeland, W. C., Kuchta, R. D. (1999) "Interactions of DNA with Human DNA Primase Monitored with Photoactivateable Crosslinking Agents: Implications for the Role of the p58 Subunit" Biochemistry, 38, 12899-12907. Kirk, B. W. and Kuchta, R. D. (1999) "Human DNA Primase: Anion Inhibition, Manganese Stimulation, and Their Effects on in vitro Start Site Selection" Biochemistry, 38, 10126-10134. Kirk, B. W. and Kuchta, R. D. (1999) "Arg304 of Human DNA Primase Is a Key Contributor to Catalysis and NTP Binding: Primase and the Family X Polymerases Share Significant Sequence Homology" Biochemistry, 38, 7727-7736.