YanZheng HE - 澳门大学 - 健康科学学院

个人简介

Education Ph.D. Department of Vascular Surgery, Shanghai Second Medical University, Shanghai, China (1993-1996) M.S. Surgery, Chongqing Medical University, Chongqing, China (1988-1991) B.S. School of Clinical Medicine, Luzhou Medical College, Luzhou, China (1981-1986) Academic and Professional Experience 2017.08-present Adjunct Professor, Faculty of Health Sciences, University of Macau 2016.02-present President, Southwest Medical University, Luzhou, China 2011.11-2016.02 Dean/Chair Professor, Affiliated Hospital of Luzhou Medical College, China 2005.09-2008.10 Dean, Nursing School of Luzhou Medical College, China 2002.05-2011.11 Vice President, Affiliated Hospital of Luzhou Medical College, China 1999.05-2005.09 Director, Vascular Surgery Department, Affiliated Hospital of Luzhou Medical College, China 1994.03-1996.05 Ph.D. candidate researcher, State Key Laboratory of Genetic Engineering in Fudan University

研究领域

Stem cell transplantation for ischemic limb Diabetes Acute pancreatitis and small intestine against ischemia/reperfusion injury Genome Atherosclerosis and Thrombosis

近期论文

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Representative Publications in recent 5 years Xiao-lei Sun, Betty Yuen-Kwan Law, Ivo Ricardo de Seabra Rodrigues Dias, Simon Wing Fai Mok, Yan-zheng He*, Vincent Kam-Wai Wong. Pathogenesis of thromboangiitis obliterans: Gene polymorphism and immunoregulation of human vascular endothelial cells. Atherosclerosis 2017 Aug 18. pii: S0021-9150(17)31231-5. doi: 10.1016/j.atherosclerosis.2017.08.009. Yong Liu, Wei-Ming Wang, Xue-Lin Zhang,* Hu-Qiang He, Xiao-Lei Sun, Hong Zeng, Xiong-Fei Xu, Liang Huang, Zhi Zhu, Lei Zhang, Xiang-Yu Zhou, and Yan-Zheng He*. AGE/RAGE promotes thecalcification of human aortic smooth muscle cells via the Wnt/β-catenin axis. Am J Transl Res. 2016 Nov 15;8(11):4644-4656 Sun X, Jiao X, Ma Y, Liu Y, Zhang L, He Y*, Chen Y. Trimethylamine N-oxide induces inflammation and endothelial dysfunction in human umbilical vein endothelial cells via activating ROS-TXNIP-NLRP3 inflammasome. Biochem Biophys Res Commun. 2016 Dec 2;481(1-2):63-70. L Song, S Shi, W Jiang, X Liu, Y He*. Protective role of propofol on the kidney during early unilateral ureteral obstruction through inhibition of epithelial-mesenchymal transition. Am J Transl Res 2016;8(2):460-472 Li Song, Shi Sen, Yuhong Sun, Jun Zhou, Liqun Mo, Yanzheng He*. Ketamine inhalation ameliorates Ovalbumin-induced murine asthma by suppressing the epithelial-mesenchymal transition. Med Sci Monit, 2016; 22: 2471-2483 Liu Y, Liao WJ, Zhu Z, Zeng H, He HQ, Sun XL, Xu XF, Huang L, Wang WM, Zhou XY, He YZ*. Effect of procyanidine on VEGFR-2 expression and transduction pathway in rat endothelial progenitor cells under high glucose conditions. Genet Mol Res. GMR, 2016,15(1) Yong Liu, Lei Zhang, Hong Zeng, Xiao-Lei Sun, Hu-Qiang He, Wei-Ming Wang, Liang Huang, Xue-Lin Zhang, Wen-Jun Liao, Yan-Zheng He*. PDGF-BB activated Rac-1 in regulation of inner and outer nuclear distribution of rat aortic smooth muscle cell β-catenin. Int J Clin Exp Med. 2016;9(11):20801-20813. Zhou X, Liu Z, Cheng X, Zheng Y, Zeng F, He Y*.Socs1 and Socs3 degrades Traf6 via polyubiquitination in LPS-induced acute necrotizing pancreatitis, Cell Death Dis,2015,6:e2012-e2012. Hu-Qiang He,Yong Liu, Hong Zeng, Xiao-Lei Sun, Lei Zhang, Xue-Lin Zhang, Wen-Jun Liao, Xiang-Yu Zhou, Yan-Zheng He*. Advanced glycation endproducts regulate smooth muscle cells calcification in cultured HSMCs. Int J Clin Exp Patho. 2015,8(10):12260-12267. Yong Liu, Fei Xei, Xiong-Fei Xu, Hong Zeng , Hu-Qiang He , Lei Zhang , Ying-Qiang Zheng, Yan-Zheng He*. Experimental study on apoptosis of TNFR1 receptor pro-endothelial progenitor cells activated by highglucose induced oxidative stress. Int J Clin Exp Med. 2015 Nov 15;8(11):19969-81.eCollection 2015. Zhou X, Liu Z, Jang F, Xiang C, Li Y, He Y*.Autocrine Sonic hedgehog attenuates inflammation in cerulein-induced acute pancreatitis in mice via upregulation of IL-10. PLoS One. 2012;7(8):e44121. Zhou X, Yuan P, He Y*. Role of microRNAs in peripheral artery disease. Mol Med Rep.2012 Oct;6(4):695-700. He X, Zheng Y, Liu S, Shi S, Liu Y, He Y, Zhang C, Zhou X.miR-146a protects small intestine against ischemia/reperfusion injury by down-regulating TLR4/TRAF6/NF-κB pathway. J Cell Physiol. 2017 Aug 3. doi: 10.1002/jcp.26124. Wang X, He X, Deng X, He Y, Zhou X.Roles of miR‑4463 in H2O2‑induced oxidative stress in human umbilical vein endothelial cells. Mol Med Rep. 2017 Sep;16(3):3242-3252. Xu JY, Chang NB, Li T, Jiang R, Sun XL, He YZ, Jiang J. Endothelial Cells Inhibit the Angiotensin II Induced Phenotypic Modulation of Rat Vascular Adventitial Fibroblasts. J Cell Biochem. 2017 Feb 20. doi: 10.1002/jcb.25941. He XM, Zheng YQ, Liu SZ, Liu Y, He YZ, Zhou XY. Altered Plasma MicroRNAs as Novel Biomarkers for Arteriosclerosis Obliterans, J Atheroscler Thromb, 2016,23(2):196-206. Zhu J, Xia J, Jiang J, Jiang R, He Y, Lin H.Effects of estrogen deprivation on expression of aquaporins in rat vagina. Menopause. 2015 Aug;22(8):893-8. Sen S, He Y, Koya D, Kanasaki K. Cancer biology in diabetes. J Diabetes Investig. 2014; 5(3):251-64. *Corresponding authors

学术兼职

National Secondary Professor Vice Director of Vascular Surgery Section of Chinese Medical Association (CMA) in Sichuan Academic leader of Key Construction Course of Sichuan Provincial Health Department Leader expert of Luzhou Science and Technology Academic Committee Journal reviewer board: BMC Nephrology