Jung Woo PARK - 澳门大学 - 健康科学学院

个人简介

Education PhD Michigan State University BS Michigan State University Academic and Professional Experience 2014-present Senior Instructor, Faculty of Health Sciences, University of Macau 2008-2014 Research Scientist, Stem Cell Institute, UConn Health Center 2003-2008 Post-doctoral Fellow, UConn Health Center Course Outlines HSCI2003 Microbiology Lab HSCI4002 Stem Cell Biology and Regenerative Medicine GEST1002 Quantitative Reasoning for Social Science GEST2001 Biology in Our Daily Life

研究领域

Molecular circuitry of induced Pluripotent Stem Cells (iPSC) reprogramming Molecular mechanisms for Marfan Syndrome (MS), a genetic disease manifested in defects of mesenchymal lineages and connective tissues Regulatory mechanisms by which human Embryonic Stem Cells (hESCs) differentiate into Mesenchymal Stem Cells (MSCs) Post-transcriptional regulations in hESC/iPSC self-renewal and differentiation

近期论文

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Representative Publications Li E., Zhang Z., Jiang B., Yan L., Park J.W., and Xu R.H. Generation of mesenchymal stem cells from human embryonic stem cells in a complete serum-free condition. Int. J. Biol. Sci. 14(13):1901-9, 2018 Yang J., Park J.W., Zheng D., and Xu R.H. Universal corneal epithelial-like cells derived from human embryonic stem cells for cellularization of a corneal scaffold. Trans’l Vision Sci. & Technol. 7(5):23, 2018 Yan L., Jiang B., Li E.Q., Wang X.Y., Ling Q., Zheng D.J., Park J.W., Chen X., Cheung E., Du X., Li Y.C., Cheng G., He E.X., Xu R.H. Scalable Generation of Mesenchymal Stem Cells from Human Embryonic Stem Cells in 3D. Int. J. Biol. Sci. 14(10):1196-1210, 2018 Park J.W.#, Yang J., Xu R.H. PAX6 alternative splicing and corneal development. Stem Cells and Development. 27(6):367-377, 2018 Park J.W., Yan L., Stoddard C., Wang X.F., Yue Z.C., Crandall L., Robinson T., Chang Y.X., Denton K., Li E.Q., Jiang B., Zhang Z.W., Martins-Taylor K., Yee S.P., Yue L.X., Xu, R.H., Recapitulating and correcting Marfan Syndrome in a cellular model. Int. J. Biol. Sci. 13(5):588-603, 2017 Wang J.*, Park J.W.*, Drissi H., Wang X., and Xu R.H. Epigenetic Regulation of miR-302 by JMJD1C Inhibits Neural Differentiation of Human Embryonic Stem Cells. J. Biol. Chem. 289(4):2384-95, 2014 Brooks A.N., Yang L., Duff M.O., Hansen K.D., Park J.W., Dudoit S., Brenner S.E., Graveley B.R. Conservation of an RNA Regulatory Map Between Drosophila and Mammals. Genome Research. 21(2):193-202, 2011 Zeng H., Guo M., Martins-Taylor K., Wang X., Zhang Z., Park J.W., Zhan S., Kronenberg M.S., Lichtler A., Liu H.X., Chen F.P., Yue L., Li, X.J., Xu R.H. Specification of Region-specific Neurons Including Forebrain Glutamatergic Neurons From Human Induced Pluripotent Stem Cells. PLoS ONE. 5(7):e11853, 2010 Zeng H., Park J.W., Guo M., Lin G., Li X., Chen F., Xu R.H. Lack of ABCG2 Expression and Side Population Properties in Human Pluripotent Stem Cells. Stem Cells. 27(10):2435-45, 2009 Voss P.G., Gray R.M., Dickey S.W., Wang W., Park J.W., Kasai K.I., Hirabayashi, J., Patterson R.J., and Wang J.L. Dissociation of the carbohydrate-binding and splicing activities of galectin-1. Arch Biochem Biophys. 478(1):18-25. Epub, 2008. Olson S., Blanchette M., Park J.W., Savva Y., Yeo G., Yeakley J., Rio D., and Graveley B.R. A regulator of Dscam mutually exclusive splicing fidelity. Nature Struct and Mol Biol. 14:1134 – 1140, 2007 Yang L., Park J.W., and Graveley B.R. Splicing from the outside in. Molecular Cell. 27:861-2, 2007 Park J.W. and Graveley B.R. Complex alternative splicing. In Alternative splicing in the postgenomic era. edited by Graveley B.R. and Blencowe B. Eurekah Biosciences. 623:50-63, 2007 Wang W.*, Park J.W.*, Wang J.L., and Patterson R.J. Immunoprecipitation of spliceosomal RNAs by antisera to galectin1-1 and galectins-3 (*equal contribution). Nucleic Acids Res. 34:5166-74, 2006 Park J.W. and Graveley, B.R. The use of RNA interference to dissect the roles of trans-acting factors in alternative pre-mRNA splicing. Methods. 37:341-4, 2005 Philips D.L., Park J.W. and Graveley B.R. A computational and experimental approach towards a priori identification of alternatively spliced exons. RNA. 10:1838-1844, 2004 Park J.W., Parisky K., Celotto A., Reenan R.A., and Graveley B.R. Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci USA. 101:15974-15979, 2004 Park J.W., Voss P., Grabski S., Wang J.L., and Patterson R.J. Association of galectins-1 and galectins-3 with Gemin4 in complexes containing the SMN protein. Nucleic Acids Res. 27(17):3595-3602, 2001 Patterson R.J., Park J.W., and Wang J.L. Intracellular functions of galectins. Recent Res. Dev. Mol. Cell. Biol. 2:233-245, 2001