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个人简介

教育经历: 2006.9-2010.6 美国加州大学戴维斯分校,获化学哲学博士学位 研究方向:杂环合成化学、药物化学及组合化学,指导教授:Mark J. Kurth, Ph.D. 1997.9-1999.12 美国俄亥俄州立克利夫兰大学,获理学硕士学位 研究方向:铟的二元桥式配位化合物的合成,指导教授:Stanley Duraj, Ph.D. 1991.9-1994.4 华中科技大学化学与化工学院,获硕士学位 研究方向:基于氮杂轮烯敏感膜的二氧化氮传感器的研制,指导教授:李焰 1987.9-1991.7 东北大学化学系,获学士学位 工作经历: 2012.5-现在 武汉科技大学化学工程与技术学院,校特聘教授 2010.8-2011.9 美国得克萨斯大学西南医学中心,博士后研究员 2005.5-2006.8 美国强生公司/Johnson and Johnson,高级副研究员 2001.1-2005.5 美国瑞萨卡生物科技公司/Ricerca Bio. LLC., 高级副研究员 2000.1-2000.12 美国高分子标准物公司,合成化学师 1994.5-1997.7 华中科技大学, 讲师

研究领域

抗肿瘤天然产物的合成、不对称催化反应、抗肿瘤和抗帕金森症药物的研发、药物化学、杂环化学

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Ye, L.; Dickerson, T.; Kaur, H.; Takada, Y.; Fujita, M.; Liu, R.; Knapp, J.; Lam, K.; Schore, N. E.; Kurth, M.J.; Takada, Y. Identification of Inhibitors against Interaction between Pro-inflammatory sPLA2-IIA Protein and Cell Receptor Integrin αvβ3 Bioorganic and Medicinal Chemistry, 2013,23(1),340-345 <影响因子(Impact factor): 2.7, SCI > 2. Ye, L; Haddadin, J. M; Lodewyk, W. M.; Tantillo, J. D.; Fettinger J. C.; Kurth, J. M. Cyclopenta[b]pyrroles from Triazines: Synthetic and Mechanistic Studies. Organic Letters 2010, 12, 164-167 <影响因子(Impact factor): 5.8, SCI,有机化学一区 > 3. Ye, L.; Knapp, M. J.; Panjamaporn W.; Verkman A. S.; Kurth M. J. Pyrazolylthiazoles ad F508-CFTR Correctors with Improved Hydrophilicity Compared to Bithiazoles. Journal of Medicinal Chemistry 2010, 53, 3772-3781, <影响因子(Impact factor): 5.5, SCI,药物化学一区> 4. Milinkevich, K. A.; Ye, L.(主要化合物的合成及关键步骤的实现); Kurth, M. J. Synthesis of 5-(Thiazol-5-yl)-4,5-dihydroisoxazoles from 3-Chloropentane-2,4-dione. Journal of Combinatorial Chemistry 2008, 10(4), 521-525.<影响因子(Impact factor): 3.5, SCI> 5. Yao, N; Fung, G; Malekan, H; Ye, L;Kurth, M. J.; Lam, K. S Facile Synthesis of Glycosylated Fmoc-amino acid Building Blocks Assisted by Microwave Irradiation. Carbohydrate Research 2010, 345(15), 2277-2281 <影响因子(Impact factor): 2.2, SCI> 6. Reddy, N. L.; Hill, J.; Ye, L. (主要化合物的合成); Fernades, P.; Stout, D. Identification and structure-activity relationship studies of 3-methylene-2-norboranone as potent anti-proliferative agents presumably working through p53 mediated apoptosis Bioorganic & Medicinal Chemistry Letters, 2004, 14, 5645-5649 <影响因子(Impact factor): 2.7, SCI> 7. Duraj, S. A.; Browne, R. Al-Fawaz, A.; Ye, L.; Wolf, J.; Hepp, A. F.; Harris, J. D.; Fanwick, P. E.; Cowen, J. Recent synthetic studies of Ga and In compounds from our laboratories. Abstracts of Papers, 220th ACS National Meeting, Washington, DC, United States, August 20-24, 2000, INOR-439. 8. Ye, L; Jin, X.; Wang, X.; Zhang, X. Pb-doped microwave dielectric ceramics in BaO-Nd2O3-TiO2 system and its lower frequency test experiment. Gongneng Cailiao (Functional Materials,EI index) 1998, 29(1), 75-78 9. Pan, X.; Tang, Q.; Ye, L. Study of humidity sensing properties of ZnO-SnO2-Cr2O3 semiconducting ceramics at high temperatures. Chuangan Jishu Xuebao (Jouranl of Transducer Technology,EI index) 1996, 9(3), 8-12. 10. Li, Y.; Ye, L.; Li, A. Novel film electric-conduction type gas sensor for determination of NO2 in flue gas. Huazhong Ligong Daxue Xuebao (EI index )1997, 25(1), 53-56 11. Pan, X.; Tang, Q.; Ye, L. Influences of heat treatment on electrical characteristics of ZrO2 (8 mol% Y2O3) solid electrolyte. Gongneng Cailiao (Functional Materials,EI index) 1996, 27(4), 353-356 12. Shi, K.; Pan, X.; Tang, Q.; Ye, L. A New Type of High Power Oxide Conductive Ceramics. Huazhong Ligong Daxue Xuebao(EI index) 1996, 24(1), 93-94 13. Li, Y.; Ye, L.; Zhu, Y. Study on preparation of LB film with tetramethyldibenzo-tetraazaannulene complex with nickel (Ni-TMTAA). Gongneng Cailiao (Functional Materials, EI index) 1995, 26(Suppl.), 637-638 14. Ye, L. NO2 sensors Using Tetraaza[14]annulene and its Metal Complexe Films as Sensitive Elements. (in English), The proceeding of East Asia Conference on Chemical Sensors (held concurrently with IEEE’s Conference On Sensors and Actuators,EI index), Xi’an, China Oct.5, 1995 15. Ye, L; Li, Y. Retention Behavior of Isomers of Dichlorobenzene and Several Simple Alcohols on Chromatographic Column Containing-cyclodextrine. The Proceeding of the 9th National Chromatography Symposium, Qingdao, China; July 1, 1993 16. Li, W.; Carroll, C.; Ye, L. De Brabander, J. K.; Total Synthesis of Mangrolide A (准备中)

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