个人简介
Professor Jiye Cai, man, PhD, supervisor of doctoral students. 1962-1968 studied and
graduated from Beijing University, Department of Physics;1983-1985, visiting scholar
at Columbia University, Columbia Radiation laboratory; He finished his PhD degree
from Chinese Academy of Sciences, supervised by professor George W Flynn and
Songhao Liu;1992-1994 was senior visiting scholar at Stanford University, Department
of Chemistry. He was a major contributor for high resolution, high speed and high
sensitivity diode laser probe, and by using this new method, for the first time, obtained
vibrationally and rotationally resolved dynamic spectrum of three atom molecule. He
participated “hither to the most sophisticated experiment” in physical
chemistry----impact parameter dependence of chemical reaction. He and his
collaborator had published more than 100 SCI papers, and 6 patents and a book. He was
invited to give talks at more than 10 universities and his papers were quoted more than
500 times by other researchers. He had finished 6 Chinese National Natural Science
Foundations and Special Foundations by Chinese Department of Science and
Technology. He has trained over 60 graduate students and many of them own Yilida
Prize, Daheng Prize, Excellent Graduated Students of University of Science and
Technology of China and South China Excellent Student Prize. Part of his research
results have obtained First Grade Prize of Natural Science of Guangdong Province
(1996), First Grade Prize of Guangdong High Education Bureau (1996) and First Grade
Prize of Science and Technology Progress Award (2011).
The research fields of professor Jiye Cai include bionanotechnology, single molecule in
situ detection on cell membrane and cell ultrastructures, Quantum Dots marked
bio-molecule distribution, and the effect and mechanism of Chinese medicine against
cell ultrastructures, etc.
Education:
1962.8-1968.7, Studied at Beijing University, Department of Physics
1983.8-1987.7, PhD, Chinese academy of Science
Professional Chronology:
1979.1-1998.6 Chinese Academy of Sciences, Anhui Institute of Optics and Fine
Mechanics, research associate, associate professor, professor,
advisor of doctoral students
1983.9-1985.10 Columbia University, Columbia Radiation laboratory; Visiting
Scholar
1992.9-1994.1 Stanford University, Department of Chemistry, Senior Visiting
Scholar
1994.2-1994.12 UWO University, Chemical Physics Center, Visiting Professor
1998.7-now Jinan University, Department of Chemistry, Professor, Vice Dean
of College of Life Science and Technology
2013-now State Key Laboratory for Quality Research in Chinese Medicine,
Macau University of Science and Technology, Distinguished
Professor
Teaching Subjects:
(1) Bionanotechnology (For PhD students)
(2) Nanoscience and technology (For graduated students)
近期论文
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1) Huai-Hong Cai,Pei-Hui Yang, HuiWang, Lian-XiHuang, Shi-Xian Wu, Jiye Cai.
Label-free oligonucleotide detection method based on a new L-cysteine-
dihydroartemisinin complex electroactive indicator. Electrochemistry
Communications. 2010, 12(10):1294-1297.
2) MuWang, YuxiaRuan, XiaoboXing, QianChen, YuanPeng, JiyeCai. Curcumin
induced nanoscale CD44 molecular redistribution and antigen–antibody interaction
on HepG2 cell surface. Analytica Chimica Acta 2011, 697:83-89
3) Xiaofang Cai, Xiaoxi Yang, Jiye Cai, ShixianWu, Qian Chen.Atomic Force
Microscope-Related Study Membrane-Associated Cytotoxicity in Human Pterygium
Fibroblasts Induced by Mitomycin C. The Jornal of Physical Chemistry. 2010,
114(11):3833-3839.
4) Jiang Pi,Hua Jin, Jiye Cai, et al. Pathway of cytotoxicity induced by folic acid
modified selenium nanoparticles in MCF-7 cells. Appl Microbiol Biotechnol (2013)
97:1051– 1062
5) Hua Jin, Jiang Pi, Jiye Cai, et al. BMP2 promotes migration and invasion of breast
cancer cells via cytoskeletal reorganization and adhesion decrease: an AFM
investigation Appl Microbiol Biotechnol (2012) 93:1715– 1723
6) Hua Jin, Jiang Pi, Xun Huang, Feicheng Huang,Wenxiang Shao, Shengpu Li, Yong
Chen, Jiye Cai.BMP2 promotes migration and invasion of breast cancer cells via
cytoskeletal reorganization and adhesion decrease: an AFM investigation. Appl
Microbiol Biotechnol (2012) 93:1715–1723
7) Chen Y, Shao L, Ali Z, Cai J, Chen ZW. NSOM/QD-based nanoscale
immunofluorescence imaging of antigen-specific T-cell receptor responses during an
in vivo clonal V{gamma}2V{delta}2 T-cell expansion. Blood. 2008, 15;111
(8):4220-32.
8) Yueqin Qiu, Jianbo Chen, Hongying Liao, Yan Zhang, Hua Wang, Shaoyuan Li,
Yanfen Luo, Danyun Fang, Guobao Li, Boping Zhou, Ling Shen, Crystal Y. Chen,
Dan Huang, Jiye Cai, Kaiyuan Cao, Lifang Jiang, Gucheng Zeng, Zheng W Chen.
Tim-3-expressing CD4+and CD8+T Cells in human tuberculosis (TB) exhibit
polarized effector memory phenotypes and stronger anti-TB effector functions.
PLoS Pathogens 8(11): e1002984.
9) Hua Jin, Peihui Yang, Jiye Cai, Jinhui Wang, Mei Liu. Photothermal effects of
folate-conjugated Au nanorods on HepG2 cells. Appl Microbiol Biotechnol (2012)
94:1199–1208
10) Hua Jin, Xun Huang, Yong Chen, Hongxia Zhao, Hongyan Ye, Feicheng Huang,
Xiaobo Xing, Jiye Cai. Photoinactivation effects of hematoporphyrin monomethyl
ether on Gram-positive and -negative bacteria detected by atomic force microscopy.
Appl Microbiol Biotechnol (2010) 88:761–770
11) Hua Jin, Xing Zhong, Zhiyong Wang, Xun Huang, Hongyan Ye, Shuyuan Ma,
Yong Chen, Jiye Cai. Sonodynamic Effectsof Hematoporphyrin Monomethyl Ether
on CNE-2 Cells Detected by Atomic Force Microscopy. Journal of Cellular
Biochemistry 112:169–178 (2011)
12) H Zhao, H Jin, J Cai, S Ding. The process of collagen biomineralization observed by
AFM in a model dual membrane diffusion system. Ultramicroscopy 110 (2010)
1306–1311
13) HuaJin, XingZhong, ZhiyongWang, XunHuang, HongyanYe, ShuyuanMa,
YongChen, JiyeCai. Sonodynamic Effects of Hematoporphyrin Monomethyl
EtheronCNE-2 Cells Detected by Atomic Force Microscopy. Journal of Cellular
Biochemistry. 2011, 112:169–178.
14) Xiaofang Cai, Pengtao You, Jiye Cai, Xiaoxi Yang, QianChen, Feicheng Huang.
ART-induced biophysical and biochemical alterations of Jurkat cell membrane.
Micron. 2011,4:217-228.
15) JiananChen, Yin Pei, Zhengwei Chen, Jiye Cai. Quantum dot labeling based on
near-field optical imaging of CD44 molecules. Micron. 2010, 41(3):198-202
16) MuWang, YuxiaRuan, QianChen, ShengpuLi, QiulanWang, JiyeCai. Curcumin
induced HepG2 cell apoptosis-associated mitochondrial membrane potential and
intracellular free Ca2+ concentration. European Journal of Pharmacology. 2011,
650:41-47.
17) Wu, Yangzhe, Hu, Yi, Chen, Jianan, Cai, Jiye, He, Xianhui. Activation- induced
Reorganization in Membrane Nanostructures and Alteration in Adhesion of CD4 + T
Lymphocytes Exploited by AFM/LFM. CurrentNanoscience. 2011, 7(3):420-426.
18) Huai-Hong Cai, XingZhong, Pei-Hui Yang,WeiWei, Jianan Chen, Jiye Cai, Probing
site-selective binding of rhodamine B to bovine serum albumin. Colloids and
Surfaces A: Physicochem. Eng. Aspects. 2010, 372:35–40.
19) Hua Jin , Xiaobo Xing , Hongxia Zhao , Yong Chen, Xun Huang, Shuyuan Ma,
Hongyan Ye , Jiye Cai. Detection of erythrocytes influenced by aging and type 2
diabetes using atomic force microscope. Biochemical and Biophysical Research
Communications. 2010,391:1698–1702
20) Hu M, Chen J, Wang J, Wang X, Ma S, Cai J, Chen CY, Chen ZW. AFM- and
NSOM-based Force Spectroscopy and Distribution Analysis of CD69 Molecules on
Human CD4+ T Cell Membrane. Journal of Molecular Recognition. 2009,
22(6):516-520
21) Hua Jin, Hongxia Zhao, Xianxian Chen, Lina Ma, XunHuang, HongyanYe, JiyeCai.
An easy method to detect the kinetics of CD44 antibody and its receptors on B16
cells using atomic force microscopy. Mol Biol Rep. 2010 1.875
22) Hua Jin, Shuyuan Ma, Bing Song, Lina Ma, Jiang Pi, Xianxian Chen, Yong Chen,
AND Jiye Cai. Liposome Impaired the Adhesion and Spreading of HEK293 Cells:
An AFM Study. Scanning. 2011, 33:1-6
23) XIE WeiLing, YANG PeiHui, ZENG Jin, WANG Hui, CAI HuaiHon, CAI JiYe.
Visual characterization of targeted effect of holo- transferrin-tagged
dihydroartemisinin on human breast cancer cells. 科学通报. 2010,
55(22):2390-2395.
24) Mou C, Chen L. Battle for Pluripotency: Derivation of Induced Pluripotent Stem
Cells. Recent Patents on Regenerative Medicine. 2011, 1:123-130
25) Zhang Y, Ouyang D, Xu L, Ji Y, Zha Q, Cai J, He X. Cucurbitacin B induces rapid
depletion of the G-actin pool through reactive oxygen species-dependent actin
aggregation in melanoma cells. Acta Biochim Biophys Sin. 2011,43(7)