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个人简介

周华教授于 2001 年由广州中医药大学博士毕业,2001 至 2002 年在美国哥伦比亚大学从事博士 后研究工作,2002 年 11 月加入香港浸会大学进行教学及研究工作。2011 年 9 月加入澳门科技 大学,任中药质量研究国家重点实验室(澳门科技大学)中药活性评价及分子药理研究室主任, 历任中医药学院课程主任、助理院长、副院长等行政职务,具有丰富的教学、研究和行政管理 经验。主要研究领域为心血管及抗炎免疫中药药理学和中药新药研发等。为澳门特别行政区政 府医务委员会委员,中国免疫学会中医药免疫分会副秘书长,世界中医药学会联合会中医药免 疫专业委员会副会长兼副秘书长,Phytomedicine 杂志副主编、Pharmacological Research 杂志荣 誉编委,国际标准化组织中医药技术委员会原药材与传统炮制质量安全工作组(ISO/TC249/WG1) 秘书及专家。曾获国家科学技术部、国家自然科学基金海外及港澳学者合作研究基金(原海外 杰青)、澳门科学技术发展基金多项资助。发表 SCI 论文近 140 篇,中文文章 50 余篇,获国际 及中国专利授权 33 项。获国家科技进步二等奖、教育部高等学校科学研究优秀成果奖自然科学 奖一等奖、澳门特别行政区科学技术奖励特等奖以及自然科学奖一等奖等各级奖励十余项。 教学科目: 中药药理学、中药新产品研究与开发、中药药理实验方法、药理实验方法学、中药复方研究与 新产品开发、专题实习、专题研究 学历 1998 - 2001 广州中医药大学 / 中西医给合 (免疫药理学) / 博士学位 1993 - 1996 广州中医药大学 / 中西医结合 (中药学) / 硕士学位 1989 - 1993 广州中医学院 / 中药学 / 学士学位 教学经验 2020.7 - 现职 澳门科技大学 / 中医药学院 / 院长 2016.7 - 现职 澳门科技大学 / 教授 2015.7 – 2020.6 澳门科技大学 / 中医药学院 / 副院长 2013.7 - 2015.6 澳门科技大学 / 中医药学院 / 助理院长 2012.7 - 2013.6 澳门科技大学 / 中医药学院 / 课程主任 2011.9 - 2016.6 澳门科技大学 / 副教授 2011.9 - 现职 中药质量研究国家重点实验室(澳门科技大学) / 中药活性评价及分子 药理研究室 / 主任 2006.1 - 2011.9 香港浸会大学 / 中医药学院 / 助理教授 香港浸会大学 / 岑尧宽岑碧泉纪念癌症炎症研究中心 / 研究员 2003.4 - 2005.12 香港浸会大学/ 中医药学院 / 研究开发部科学主任及项目主管 2002.11 - 2003.3 香港浸会大学 / 中医药学院 / 研究开发部科学主任 2001.8 - 2002.10 美国纽约哥伦比亚大学 / 医学院 / 心脏生理部博士后 1996.7 - 1998.8 广州中医药大学 / 中药系 / 药剂教研室教学及研究助理

研究领域

中药心血管及抗炎免疫药理、分子生药鉴定、中药质量研究、创新药物研究

部分研究项目(主持) 2020 - 2021 中药抗新冠状病毒表面及空气消毒剂的研制. 澳门科学技术发展基金 2020 - 2022 多基源中药大黄、黄连质量一致性评价研究及 ISO 国际中药标准研发,澳 门科学技术发展基金与广东省科学技术厅联合科研资助项目 2020 - 2023 青藤硷调控 mPGES-1 基因特异性甲基化的机理及其用于筛选新型抗炎中药 的示范研究,国家自然科学基金海外及港澳学者合作研究基金延续项目 2018 - 2021 基于体内暴露的中药附子质量标示物的挖掘、确证与应用,澳门科学技术 发展基金与国家科学技术部联合科研资助项目 2018 - 2020 基于基因组中抗性相关基因多态性的道地中药材质量研究,澳门科学技术 发展基金 2017 - 2018 中药抗炎免疫药理研究,国家自然科学基金海外及港澳学者合作研究基金 2015 - 2017 基于谱效学研究建立候选中药新药冠心康泰质量评价新方法,澳门科学技 术发展基金 2012 - 2015 基于单核苷酸多态性和药效关联分析建立评价人参质量的新方法,澳门科 学技术发展基金 2012 – 2012 人参达玛烷二醇合成酶基因单核苷酸多态性(SNP)检测方法的研究,澳门 基金会

近期论文

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部分期刊文章: (*, 责任作者; †, 共同第一作者) (1) Zuo Y-H, Liu Y-B, Cheng C-S, Yang Y-P, Xie Y, Luo P, Wang W, Zhou H*. Isovaleroylbinankadsurin A ameliorates cardiac ischemia/reperfusion injury through activating GR dependent RISK signaling. Pharmacological Research. 2020 May 16;104897. [SCI impact factor 2018: 5.574, ranked 18th in 267 journals (6.7%) of category PHARMACOLOGY & PHARMACY] (2) Huang Y-F, Bai C, He F, Xie Y, Zhou H*. Review on the potential action mechanisms of Chinese medicines in treating Coronavirus Disease 2019 (COVID-19). Pharmacological Research. 2020 May 21;104939. [SCI impact factor 2018: 5.574, ranked 18th in 267 journals (6.7%) of category PHARMACOLOGY & PHARMACY] (3) Wu W-R, Cheng C-S, Cheng Q-Q, Lao C-C, Cui H, Tang Z-Y, Ouyang Y, Liu L, Zhou H*. Novel SNP markers on ginsenosides biosynthesis functional gene for authentication of ginseng herbs and commercial products. Chinese Journal of Natural Medicines 2020 Apr 14;1–9. [SCI impact factor 2018: 1.773, ranked 13th in 27 journals (48.1%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (4) Li C, Hou S-Z, Zhou H*. Mechanism Prediction of Monotropein for the Treatment of Colorectal Cancer by Network Pharmacology Analysis. Digital Chinese Medicine. 2020 Mar 1;3(1):1–10. (5) Lio C-K, Luo J-F, Shen X-Y, Dai Y, Machado J, Xie Y, Yao Y-D, Yu Y, Liu J-X, Yao X-S, Luo P*, Zhou H*. Nardosinanone N suppresses LPS-induced macrophage activation by modulating the Nrf2 pathway and mPGES-1. Biochemical Pharmacology. 2020 Mar;173:113639. [SCI impact factor 2018: 4.825, ranked 25th in 267 journals (9.4%) of category MULTIDISCIPLINARY CHEMISTRY] (6) Wang W-Y†, Zhou H†, Liu L*. The Role of Chinese Herbal Medicine in the Management of Adverse Drug Reactions of Leflunomide in Treating Rheumatoid Arthritis. Phytomedicine. 2020 Mar;68:153136. [SCI impact factor 2018: 4.180, ranked 1st in 27 journals (3.7%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (7) Wang C-J, He F, Huang Y-F, Ma H-L, Wang Y-P, Cheng C-S, Cheng J-L, Lao C-C, Chen D-A, Zhang Z-F, Sang Z, Luo P, Xiao S-Y, Xie Y, Zhou H*. Discovery of chemical markers for identifying species, growth mode and production area of Astragali Radix by using ultra-high-performance liquid chromatography coupled to triple quadrupole mass spectrometry. Phytomedicine. 2020 Feb 1;67:153155. [SCI impact factor 2018: 4.180, ranked 1st in 27 journals (3.7%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (8) Wang H-G, Luo F-K, Lei X, Yao Y-D, Liao G-C, Liu Z-Q, Jiang Z-H, Zhou H*, Wu P. 3, 4-seco-Labdane diterpenoids from the leaves of Callicarpa nudiflora with anti-inflammatory effects. Chinese Journal of Natural Medicines. 2019 Sep 1;17(9):707–12. [SCI impact factor 2018: 1.773, ranked 13th in 27 journals (48.1%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (9) Yao Y-D, Shen X-Y, Machado J, Luo J-F, Dai Y, Lio C-K, Yu Y, Xie Y, Luo P, Liu J-X, Yao X-S, Liu Z-Q*, Zhou H* Nardochinoid B Inhibited the Activation of RAW264.7 Macrophages Stimulated by Lipopolysaccharide through Activating the Nrf2/HO-1 Pathway. Molecules. 2019 Jul 6;24(13):2482. [SCI impact factor 2018: 3.060, ranked 68th in 172 journals (39.5%) of category MULTIDISCIPLINARY CHEMISTRY] (10) Peng C, Shi Q-P, Liu J-Y, Lv Y-J, Li J, Yi L, Bai S-S, Liu L, Wang P-X, Zhou H*, Huang K-E, Dong Y*. Alpha7 nAChR Expression Is Correlated with Arthritis Development and Inhibited by Sinomenine in Adjuvant-Induced Arthritic Rats. Evidence-Based Complementary and Alternative Medicine. 2019 May 2;Article ID 3759304 (1-11). [SCI impact factor 2018: 1.984, ranked 10th in 27 journals (37.0%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (11) Zhu R-L, Zhi Y-K, Yi L, Luo J-F, Li J, Bai S-S, Liu L, Wang P-X, Zhou H*, Dong Y*. Sinomenine regulates CD14/TLR4, JAK2/STAT3 pathway and calcium signal via α7nAChR to inhibit inflammation in LPS-stimulated macrophages. Immunopharmacology and Immunotoxicology. 2019 Mar 21;1–6. [SCI impact factor 2018: 2.086, ranked 67th in 93 journals (30.3%) of category TOXICOLOGY] (12) Li C, Zhang W-Y, Yu Y, Cheng C-S, Han J-Y, Yao X-S*, Zhou H*. Discovery of the mechanisms and major bioactive compounds responsible for the protective effects of Gualou Xiebai Decoction on coronary heart disease by network pharmacology analysis. Phytomedicine. 2019 Mar 15;56:261–8. [SCI impact factor 2018: 4.180, ranked 1st in 27 journals (3.7%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (13) Zhang W-Y, Yu Y, Yan L-L, Li C, Han J-Y, Qin Z-F, Dai Y, Yao Z-H, Zhou H*, Yao X-S*. Discovery of cardio-protective constituents of Gualou Xiebai Decoction, a classical traditional Chinese medicinal formula. Phytomedicine. 2019 Feb 15;54:318–27. [SCI impact factor 2018: 4.180, ranked 1st in 27 journals (3.7%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (14) Cheng,Q.Q. †, Cheng,C.S. †, Ouyang,Y., Lao,C.C., Cui,H., Xian,Y., Jiang,Z.H., Li,W.J., Zhou,H.* Discovery of differential sequences for improving breeding and yield of cultivated Ophiocordyceps sinensis through ITS sequencing and phylogenetic analysis. Chinese Journal of Natural Medicines. 2018 Oct 22;16(10): 0749-55. [SCI impact factor 2018: 1.773, ranked 13th in 27 journals (48.1%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (15) Xiao C-X, He F, Yang M-T, Xia F, Tang W-J, Zhou B-J*, Zhou H*. Ultra-high performance liquid chromatography/triple quadrupole mass spectrometry study of the stabilities and transformations of four alisols in Alismatis Rhizoma and proprietary traditional Chinese medicine prescriptions. Pharmacognosy Magazine. 2018 Oct 1;14(58):597. [SCI impact factor 2018: 1.260, ranked 52nd in 61 journals (85.2%) of category MEDICINAL CHEMISTRY] (16) Luo J-F, Shen X-Y, Lio CK, Dai Y, Cheng C-S, Liu J-X, Yao Y-D, Yu Y, Xie Y, Luo P, Yao X-S, Liu Z-Q*, Zhou,H.* Activation of Nrf2/HO-1 Pathway by Nardochinoid C Inhibits Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages. Front Pharmacol. 2018 Aug 29;9: 911(1-19). [SCI impact factor 2018: 3.845, ranked 59th in 267 journals (22.1%) of category PHARMACOLOGY&PHARMACY] (17) Zuo,Y.H., Han,Q.B., Dong,G.T., Yue,R.Q., Ren,X.C., Liu,J.X., Liu,L., Luo,P.*, Zhou,H. * Panax ginseng Polysaccharide Protected H9c2 Cardiomyocyte From Hypoxia/Reoxygenation Injury Through Regulating Mitochondrial Metabolism and RISK Pathway. Frontiers in Physiology. 2018 Jun 15;9: 699 (1-16). [SCI impact factor 2018: 3.201, ranked 25th in 81 journals (28.9%) of category PHYSIOLOGY] (18) Huang B-M, Zha Q-L, Chen T-B, Xiao S-Y, Xie Y, Luo P, Wang Y-P, Liu L, Zhou H* Discovery of markers for discriminating the age of cultivated ginseng by using UHPLC-QTOF/MS coupled with OPLS-DA. Phytomedicine. 2018 June 1;45:8-17 [SCI impact factor 2018: 4.180, ranked 1st in 27 journals (3.7%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (19) Chen T-B, Zuo Y-H, Dong G-T, Liu L, Zhou H*. An integrated strategy for rapid discovery and identification of quality markers in Guanxin Kangtai preparation using UHPLC-TOF/MS and multivariate statistical analysis. Phytomedicine. 2018 May 15;44:239–46. [SCI impact factor 2018: 4.180, ranked 1st in 27 journals (3.7%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (20) Yi,L., Lyn,Y.J., Peng,C., Bai,S.S., Zhu,R.L., Liu,L., Wang,P.X., Zhou,H.*, Dong,Y.* Sinomenine inhibits fibroblast-like synoviocyte proliferation by regulating alpha 7nAChR expression via ERK/Egr-1 pathway. International Immunopharmacology. 2018 Mar;56:65–70. [SCI impact factor 2018: 3.361, ranked 81st in 267 journals (30.3%) of category PHARMACOLOGY & PHARMACY] (21) Ren,X.C., Chen,L., Xie,J., Zhang,Z.F., Dong,G.T., Liang,J., Liu,L., Zhou,H.*, Luo,P.* (2017) Resveratrol Ameliorates Mitochondrial Elongation via Drp1/Parkin/PINK1 Signaling in Senescent-like Cardiomyocytes. Oxidative Medicine and Cellular Longevity. 2017 October 22;4175353(1-22) [SCI impact factor 2017: 4.936, ranked 62nd in 190 journals (27.4%) of category CELL BIOLOGY] (22) Zhou,H.†, Liu,J.X.†, Luo,J.F., Cheng,C.S., Leung,E.L.H., Li,Y., Su,X.H., Liu,Z.Q., Chen,T.B., Duan,F.G., Dong,Y., Zuo,Y.H., Li,C., Lio,C.K., Li,T., Luo,P., Xie,Y., Yao,X.J., Wang,P.X., Liu,L. (2017) Suppressing mPGES-1 expression by sinomenine ameliorates inflammation and arthritis. Biochemical Pharmacology. 2017 October 15; 142: 133-144. DOI: 10.1016/j.bcp.2017.07.010 [SCI impact factor 2017: 4.235, ranked 36th in 261 journals (13.8%) of category PHARMACOLOGY&PHARMACY] (23) He,F. †, Wang,C.J. †, Xie,Y., Cheng,C.S., Liu,Z.Q., Liu,L. *, Zhou,H.* (2017) Simultaneous quantification of nine aconitum alkaloids in Aconiti Lateralis Radix Praeparata and related products using UHPLC–QQQ–MS/MS. Scientific Reports. 2017 Oct 12;7(1): 13023(1–12). [SCI impact factor 2017: 4.122, ranked 12th in 64 journals (18.8%) of category MULTIDISCIPLINARY SCIENCES] (24) Huang,B.M., Chen,T.B., Xiao,S.Y., Zha,Q.L., Luo,P., Wang,Y.P., Cui,X.M., Liu,L., Zhou,H.* (2017) A new approach for authentication of four ginseng herbs and their related products based on the simultaneous quantification of 19 ginseng saponins by UHPLC-TOF/MS coupled with OPLS-DA. RSC Advances. 2017 September 19;7:46839-51 [SCI impact factor 2017: 2.936, ranked 71st in 170 journals (41.8%) of category MULTIDISCIPLINARY CHEMISTRY] (25) Cheng,C.S., Wang,C.J., Liang,J., Lao,C.C., Zhou,H.*, Zhang,Z.F.* (2017) A new approach for identification of medicinal almonds by fourier transform infrared spectroscopy and systematic clustering of characteristic peaks. Chinese Journal of Natural Medicines. 2017 Sep;15(9):703–9. 6 [SCI impact factor 2017: 1.991, ranked 11th in 27 journals (40.7%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (26) Huang,B.M., Xiao,S.Y., Chen,T.B., Xie,Y., Luo,P., Liu,L., Zhou,H.* (2017) Purity assessment of ginsenoside Rg1 using quantitative 1H nuclear magnetic resonance. Journal of Pharmaceutical and Biomedical Analysis. 2017 Mar 6; 139: 193-204. DOI: 10.1016/j.jpba.2017.02.055 [SCI impact factor 2017: 2.831, ranked 22nd in 79 journals (27.8%) of category ANALYTICAL CHEMISTRY] (27) Wu,P., Gao,H., Liu,J.X., Liu,L., Zhou,H.*, Liu,Z.Q.* (2017) Triterpenoid saponins with anti-inflammatory activities from Ilex pubescens roots. Phytochemistry. 2017;134:122-32. [SCI impact factor 2017: 3.186, ranked 34th in 222 journals (15.3%) of category PLANT SCIENCES] (28) Wu,J., Xie,Y., Xiang,Z., Wang,C.J., Zhou,H.*, Liu,L.* (2016) Simultaneous Determination of Multiple Components in Guanjiekang in Rat Plasma via the UPLC–MS/MS Method and Its Application in Pharmacokinetic Study. Molecules. 2016 Dec 16;21(12):1732. [SCI impact factor 2016: 2.861, ranked 17th in 59 journals (28. 8%) of category ORGANIC CHEMISTRY] (29) Xiao,L., Yi,T., Lam,C.W.K.*, Zhou,H.* (2016) A new mechanism for increasing the oral bioavailability of scutellarin with Cremophor EL: activation of MRP3 with concurrent inhibition of MRP2 and BCRP. European Journal of Pharmaceutical Sciences. 2016 Oct 10;93:456-67. [SCI impact factor 2016: 3.756, ranked 54th in 256 journals (21.1%) of category PHARMACOLOGY & PHARMACY] (30) Cheng,C.S., Wu,W.R., Huang,B.M., Liu,L., Luo,P., Zhou,H.* (2016) SNPs of dammarenediol synthase gene were associated with the accumulation of ginsenosides in DAMAYA ginseng, a cultivar of Panax ginseng C. A. Mey. Phytochemistry Letters. 2016 Sep;17:194–200. [SCI impact factor 2016: 1.418, ranked 100th in 211 journals (47.4%) of category PLANT SCIENCES] (31) Liu,J.X., Tang,J.S., Zuo,Y.H., Yu,Y., Luo,P., Yao,X.S., Dong,Y., Wang,P.X., Liu,L.*, Zhou,H.* (2016) Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signaling. Pharmacological Research. 2016 June 22;111:303-15 [SCI impact factor 2016: 4.480, ranked 31st in 256 journals (12.1%) of category PHARMACOLOGY & PHARMACY] (32) Xiao,L., Yi,T., Liu,Y., Zhou,H.* (2016) The in vitro lipolysis of lipid-based drug delivery systems: a newly identified relationship between drug release and liquid crystalline phase. BioMed Research International. 2016 May 16; 2016:e2364317. [SCI impact factor 2016: 2.476, ranked 65th in 158 journals (41.1%) of category BIOTECHNOLOGY & APPLIED MICROBIOLOGY] (33) Cheng,C.S., Yuan,Q.X., Zhou,H.*, Huang,L.Q.* (2016) Nondestructive estimation of growth year in ginseng cultivars using the means of mathematical modeling on the basis of allometry. Microscopy Research and Technique. 2016 Feb 01;79(2):98-105 7 [SCI impact factor 2016: 1.147, ranked 13th in 21 journals (61.9%) of category ANATOMY & MORPHOLOGY] (34) Dong,G.T., Chen,T.B., Ren,X.C., Zhang,Z.F., Huang,W.X., Liu,L., Luo,P.*, Zhou,H.* (2016) Rg1 prevents myocardial hypoxia/reoxygenation injury by regulating mitochondrial dynamics imbalance via modulation of glutamate dehydrogenase and mitofusin 2. Mitochondrion. 2016;26:7-18 [SCI impact factor 2016: 3.704, ranked 51st in 166 journals (30.7%) of category GENETICS & HEREDITY] (35) Wang,C.J, Xie,Y., Xiang,Z., Zhou,H.*, Liu,L.*. (2015) Simultaneous determination of thirteen major active compounds in Guanjiekang preparation by UHPLC-QQQ-MS/MS. Journal of Pharmaceutical and Biomedical Analysis. 2015 Nov 7. 118:315–321 [SCI impact factor 2015: 3.169, ranked 14th in 75 journals (18.67%) of category ANALYTICAL CHEMISTRY] (36) Luo,P., Dong,G.T., Liu,L., Zhou,H.* (2015) The long-term consumption of ginseng extract reduces the susceptibility of intermediate-aged hearts to acute ischemia reperfusion injury. PLOS ONE. 2015 Dec 9. 10(12):e0144733 [SCI impact factor 2015: 3.057, ranked 11th in 63 journals (17.46%) of category MULTIDISCIPLINARY SCIENCES] (37) Li,T., Wong, V.K.W., Jiang, Z.H., Liu, Y., Wang, T.Y., Yao,X.J., Su, X.H., Yan, F.G., Liu, J., Leung, E.L.H., Yi, X.Q., Wong, Y.F., Zhou,H.*, Liu,L.*, (2015) Mutation of cysteine 46 in IKK-beta increases inflammatory responses. Oncotarget. 2015 Sep 10. 6(31):31805-31819 [SCI impact factor 2015: 5.008, ranked 36th in 213 journals (16.90%) of category ONOCOLOGY] (38) Yi, L., Luo, J.F., Xie, B.B., Liu, J.X., Liu, L., Wang, P.X., Zhou, H.*, Dong, Y.* (2015) Alpha7 nicotinic acetylcholine receptor is a novel mediator of sinomenine anti-inflammation effect in macrophages stimulated by lipopolysaccharide. Shock. 2015 Aug 44(2):188-195 [SCI impact factor 2015: 3.048, ranked 33th in 199 journals (16.58%) of category SURGERY] (39) Chen, T.B., Xiang, Z., Dong, G.T., Luo, P., Qiu, P., Wang, S.Z., Huang, B.M., Wen, Y.Y., Wu, F.C., Liu, L.*, Zhou, H.*. (2015) An ultra-high performance liquid chromatographic-tandem mass spectrometric method for the determination of sinomenine in human plasma after transdermal delivery of the Zhengqing Fengtongning Injection. Molecules. 2015 Apr 10;20(4):6454–65. [SCI impact factor 2015: 2.465, ranked 24th in 59 journals (40.68%) of category ORGANIC CHEMISTRY] (40) Luo,P., Hou,S.Z., Dong,G.T, Chen,T.B., Liu,L., Zhou,H.* (2013) Effectiveness of Panax ginseng on acute myocardial ischemia reperfusion injury was abolished by flutamide via endogenous testosterone-mediated Akt pathway. Evidence-Based Complementary and Alternative Medicine. 2013 September 9. Volume 2013, Article ID 817826, http://dx.doi.org/10.1155/2013/817826. [SCI impact factor 2013: 2.175, ranked 6th in 22 journals (27.3%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] 8 (41) Wang,T.Y.†, Zhou,H.†, Leung,E., Wong,Y.F., Wu,P.K., Hsiao,W. Leung, E.L.H., Liu,L. (2013) The Predicted Proteomic Network Associated with the Antiarthritic Action of Qingfu Guanjieshu in Collagen-II-Induced Arthritis in Rats. Evidence-Based Complementary and Alternative Medicine. 2013 May 28; Volume 2013, Article ID 582493, http://dx.doi.org/10.1155/2013/582493. [SCI impact factor 2013: 2.175, ranked 6th in 22 journals (27.3%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (42) Wang,J.R., Zhou,H., Yi,X.Q., Jiang,Z.H., Liu,L. (2012) Total ginsenosides of radix ginseng modulates tricarboxylic acid cycle protein expression to enhance cardiac energy metabolism in ischemic rat heart tissues. Molecules. 2012 Oct 29;17(11):12746-12757. [SCI impact factor 2012: 2.386, ranked 24th in 57 journals (42.1%) of category ORGANIC CHEMISTRY] (43) Fan,Y.F., Xie, Y., Liu, L., Ho, H.M., Wong, Y.F., Liu,Z.Q.*, Zhou,H.* (2012) Paeoniflorin reduced acute toxicity of aconitine in rats is associated with the pharmacokinetic alteration of aconitine. Journal of Ethnopharmacology. 2012 Jun; 141(2):701-708. [SCI impact factor 2012: 3.322, ranked 3rd in 22 journals (13.6%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE] (44) Hou,S.Z., Su,Z.R., Chen,S.X., Ye,M.R., Huang,S., Liu,L., Zhou,H.*, Lai,X.P.* (2011) Role of the interaction between puerarin and the erythrocyte membrane in puerarin-induced hemolysis. Chemico-Biological Interactions. 2011 Jul 15;192(3):184-92. [SCI impact factor 2011: 2.832, ranked 28th in 83 journals (33.7%) of category TOXICOLOGY] (45) Zhou,H.*, Hou,S.Z., Luo,P., Zeng,B., Wang,J.R., Wong,Y.F., Jiang,Z.H., Liu,L.* (2011) Ginseng protects rodent hearts from acute myocardial ischemia reperfusion injury through GR/ER-activated RISK pathway in an endothelial NOS-dependent mechanism. Journal of Ethnopharmacology. 2011 May 17;135(2):287-98. [SCI impact factor 2011: 3.014, ranked 31st in 190 journals (16.3%) of category PLANT SCIENCES] (46) Luo,P.†, Wong,Y.F.†, Ge,L., Zhang,Z.F., Liu,Y., Liu,L., Zhou,H.* (2010) Anti-inflammatory and analgesic effect of plumbagin through inhibition of nuclear factor-kappa B activation. Journal of Pharmacology and Experimental Therapeutics. 2010 Dec 1; 335;(3):735-742 [SCI impact factor 2010: 4.017, ranked the 40th out of 252 journals (15.87%) in the category of PHARMACOLOGY AND PHARMACY]. (47) Wong,V.K.W., Cheung,S.S.F., Li,T., Jiang, Z.H., Wang, J.R., Zhou,H.*, Liu,L.* (2010) Asian ginseng extract inhibits in vitro and in vivo growth of mouse Lewis lung carcinoma via modulation of ERK-p53 and NF-κB signaling. Journal of Cellular Biochemistry. 2010 Nov 1;111(4):899-910. [SCI impact factor 2010: 3.122, ranked the 125th out of 286 journals (43.71 %) in the category of BIOCHEMISTRY & MOLECULAR BIOLOGY]. (48) Yi,X.Q., Li,T., Wang,J.R., Wong,K.W.V., Luo,P., Wong,Y.F.I, Jiang,Z.H., Liu,L.*, Zhou,H.* (2010) Total ginsenosides increases coronary perfusion flow in isolated rat hearts through activation of PI3K/Akt-eNOS signaling. Phytomedicine. 2010 Aug 17; 17(13):1006-15 [SCI impact factor 2010: 2.662 ranked 3rd in 21 journals (14.29%) of category INTEGRATIVE & COMPLEMENTARY MEDICINE]. 9 (49) Li,T., Wong,K.W.V., Yi,X.Q., Wong,Y.F., Zhou,H.* & Liu,L.* (2010) Matrine induces T cell anergy in human Jurkat cells. Biological & Pharmaceutical Bulletin. 2010 Jan 33(1):40-46 [SCI impact factor 2010: 1.811, ranked 153th in 252 journals (60.71%) of category PHARMACOLOGY AND PHARMACY] (50) Zhou,H., Hou,S.Z., Luo,P., Zang,B., Wong,Y.F., Liu,L. (2009) Standardized Ginseng Extract Protects Rat Hearts From Ischemia and Reperfusion Injury via GR/PI3K/Akt/eNOS Signaling. Circulation. 120(18) S1465. [Conference Abstract] (51) Lin,J.R., Zhou,H. Lai,X.P., Hou,Y., Xian,X.M., Chen,J.N., Wang,P.X., Zhou,L., Dong,Y. (2009) Genetic Identification of Edible Birds’ Nest Based on Mitochondrial DNA Sequences. Food Research International. 42(8), 1053-1061 [SCI impact factor 2009: 2.414, ranked the 14th out of 118 journals (11.86%) in the category of Food Science & Technology]. (52) Li,T., Wong,K.W.V., Yi,X.Q., Wong,Y.F., Zhou,H.* & Liu,L.* (2009) Pseudolaric acid B suppresses T lymphocyte activation through inhibition of NK-κB signaling pathway and p38 phosphorylation. Journal of Cellular Biochemistry. 2009 September 1; 108(1):87-95. [SCI impact factor 2009: 2.935, ranked the 120th out of 283 journals (42.40%) in the category of BIOCHEMISTRY & MOLECULAR BIOLOGY] (53) Zhou,H., Wong,Y.F., Wang,J., Cai,X., Liu,L. (2008) Sinomenine Ameliorates Arthritis via MMPs, TIMPs and Cytokines in Rats. Biochemical and Biophysical Research Communications. 376(2):352-7. [SCI impact factor 2008: 2.648, ranked the 28th out of 71 journals (39.44%) in the category of BIOPHYSICS]. (54) Zhou,H. †, Wong,Y.F. †, Wang,J.R., Xie,Y., Xu,H.X., Liu,L. (2008) Anti-inflammatory and analgesic effects and molecular mechanisms of JCICM-6, a purified extract derived from an anti-arthritic Chinese herbal formula. Phytomedicine. 15(6-7):416-26. [SCI impact factor 2008: 2.330, ranked the 32nd out of 156 journals (20.51%) in the category of PLANT SCIENCES.] (55) Zhou,H., Wong,Y.F., Cai,X., Liu,Z.Q., Jiang,Z.H., Bian,Z.X., Xu,H.X., Liu,L. (2006) Suppressive effects of JCICM-6, the extract of an anti-arthritic herbal formula, on the experimental inflammatory and nociceptive models in rodents. Biological & Pharmaceutical Bulletin. 29(2):253-60. [SCI impact factor 2006: 1.522, ranked the 125th out of 199 journals (62.81%) in the category of PHARMACOLOGY AND PHARMACY]. 学术专著: (1) Research and guidance in clinical application of Zhengqing Fengtongning. (2013) Member of Editorial Committee. Public Health Publishing House 正清风痛宁研究与临床应用指南. (2013) 编委. 人民卫生出版社 (2) Safe and Proper Application of Chinese Medicine in Clinic. (2009) Vice Editor-in-Chief. Wan Li Book Co Ltd. 中医临床安全与合理用药. (2009) 副主编. 万里机构 10 (3) Encyclopedia on Medicinal Plants (Volume 4). (2009) Member of Editorial Committee. World Publishing Corporation (4) Encyclopedia on Medicinal Plants (Volume 3). (2009) Member of Editorial Committee. World Publishing Corporation (5) Encyclopedia on Medicinal Plants (Volume 2). (2009) Member of Editorial Committee. World Publishing Corporation (6) Encyclopedia on Medicinal Plants (Volume 1). (2009) Member of Editorial Committee. World Publishing Corporation (7) Chinese-English and English-Chinese Dictionary of Name of Chemical Compounds of Chinese Herbal Medicine. (2006) Member of Editorial Committee. Chinese TCM Publishing House 汉英-英汉中草药化学成分词汇. (2006) 编委. 中国中医药出版社 (8) Research Methodology and Practices in Chinese Medicine. A teaching book for Master of Chinese medicine programme of the School of Chinese Medicine (2004) Member of editor board. Hong Kong Baptist University 中医药科研方法与实践. (2004) 编委. 香港浸会大学 (9) Synonym dictionary of Chinese herbal drug. (2004) Vice editor-in-chief. Public Health Publishing House 中草药异名辞典. (2004) 副主编. 人民卫生出版社 (10) Research on preventing and curing of hepatitis. (1999) Member of editor board. Chinese TCM Publishing House 肝炎的中草药治疗. (1999) 编委. 中国中医药出版社 (11) Commonly used Chinese herbal drug. (1997) Member of translation board. Chinese TCM Publishing House 常用中草药. (1997) 翻译编委. 中国中医药出版社 (12) Research on the strategy of development biological medicine by cooperating between inland and Hong Kong. (1997) Member of editor board. Guangdong Science and Technology Publishing House 内地香港生物医药领域合作发展战略研究. (1997) 编委. 广东省科学技术出版社

学术兼职

副主编 Phytomedicine(2020.6 - ) 荣誉编辑: Pharmacological Research, 2019.11 – 常务理事: 澳门科技技术协进会监事会(2020 - 2023) 副秘书长/副会长: 世界中医药学会联合会中医药免疫专业委员会第二届理事会(2018.11 - 2023.11) 委员 Phytomedicine 编辑委员会(2018.9 - ) 副会长: 世界中医药学会联合会鉴定专业会员会(2018.8 - 2021.7) 委员 粤港澳大湾区风湿免疫医师联盟(2018.4.13 - ) 委员 澳门产品优质认证委员会(2018.1.19 - ) 委员 澳门特别行政区医务委员会(2017.8.8 - ) 副秘书长/委员 中国免疫学会中医药免疫分会(2018 – 2021) 秘书长/委员 澳门风湿病研究国际合作联盟(2016.12 – 2020.11) 委员 广东省药学会第一届岭南中草药资源专业委员会(2016.11 – 2019.11) 理事: 中俄中医药创新发展联盟第一届理事会(2016.6-2019.6) 监事: 澳门科技技术协进会监事会(2016-2019) 常务理事: 世界中医药学会联合会标准建设委员会第二届理事会(2014.12-2018.12) 副秘书长/常务理事: 世界中医药学会联合会中医药免疫专业委员会第一届理事会(2014.11- 2018.11) 常务理事: 世界中医药学会联合会药用植物资源利用与保护专业委员会第一届理事 会(2013.10-2017.10) 理事: 广东省中医药学会中药药剂与药理专业委员会(2013.9-2016.8) 会员: 广东省中医药学会(2013.9-现在) 副会长: 广东省药学会药学史专业委员会(2013.9-2016.8) 学术编辑: PLOS ONE (2013.7-现在) 常务理事: 澳门科技技术协进会(2013-2016) 常务理事: 中国药理学会抗炎免疫药理专业委员会第十一届(2012-现在) 专家/秘书: 国际标准组织中医药技术委员会原药材及传统炮制质量与安全工作组 (ISO/TC249/WG1) (2011-现在) 常务委员: 中国免疫学会中药免疫分会 ( 2009-2018) 行业专家: 香港学术及职业资历评审局 (2008-现在)

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