程纯儒 - 四川轻化工大学

个人简介

2012/7-至今 , 四川理工学院, 化学工程学院, 副教授, 教学与科研 2015/12-至今 University of Liverpool, Medicinal Chemistry, Academic Visitor, 2007/09-2012/07 中国科学院上海药物研究所，药物化学，硕博连读研究生 2003/07-2006/06 天津凯莱英医药化学有限公司，研发部，研究助理、副主管 1999/09-2003/07 四川大学华西药学院，药学，大学本科

研究领域

天然产物的分离纯化与结构修饰；药物活性分子的合成。

近期论文

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1. 程纯儒；马清萍；刘义；丁杰；曾祥丙；梁兴勇；徐凯. 一类含硫的穿心莲内酯衍生物、其药物组合物、合成方法与用途，中国，(中华人共和国国家国家知识产权局， 201510940024.X.） 2. 程纯儒；杨义；丁杰；关树宏；果德安. 赤芝子实体化学成分研究和细胞毒活性测试. 沈阳药科大学学报，02期，pp 102-106，2014. 3. *Yang, Yi; Li, Yu-Long; Cheng, Chun-Ru; Deng, Zhi-Wen; Liu, Yin-Ping; Yuan, Wei. Synthesis and Crystal Structure of Monofluorinated Iminosugar Derivative (S)-1-((3R, 4R, 5S)-1-benzyl-4-fluoro-5-((4-nitrobenzoyl)oxy)piperidin-3-yl)ethane-1,2-diyl Bis(4-nitrobenzoate). Asian Journal of Chemistry, 26(9), pp 2748-2752, 2014/5. 4. *程纯儒；丁杰；杨义；柯鸿. 间叔丁基苯乙醚的合成研究. 化学通报，05期，pp 467-470， 2014/5/18. 5. Cheng, Chun-Ru; *Yang, Min; Yu, Kate; Guan, Shu-Hong; Wu, Xiao-Hui; Wu, Wan-Ying; Sun, Yan; Li, Chuan; Ding, Jie; *Guo, De-An. Metabolite identification of crude extract from Ganoderma lucidum in rats using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 941, pp 90-99, 2013/12/15. 6. Cheng, Chun-Ru; *Yang, Min; Guan, Shu-Hong; Wu, Xiao-Hui; Pang, Xiao-Yan; Wang, Yang; Yang, Yi; Ding, Jie; *Guo, De-An. Pharmacokinetics of ganoderic acid D and its main metabolite by liquid chromatography-tandem mass spectrometry. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 930, pp 1-6, 2013/7/1. 7. *程纯儒；丁杰；杨义；杨敏；周振星；李再新. 质谱技术的新进展及其在药物研究中的应用 . 四川理工学院学报(自然科学版)，03(03), pp 11-15, 2013/6/24. 8. *Yang, Yi; Yang, Zhenjun; Cheng, Chunru; Qing, Fengling. Synthesis and Antitumor Activity Evaluation of gamma-Monofluorinated and gamma, gamma-Difluorinated Goniothalamin Analogues. Chinese Journal of Chemistry, 31(6), pp 805-812, 2013/6/1. 9. Cheng, Chun-Ru; Li, Yi-Feng; Xu, Ping-Ping; Feng, Rui-Hong; Yang, Min; Guan, Shu-Hong; Guo, De-An. Preparative isolation of triterpenoids from Ganoderma lucidum by counter-current chromatography combined with pH-zone-refining. Food Chemistry, 130(4), pp 1010-1016, 2012/03/01. 10. Cheng, Chun-Ru; *Yang, Min; Yu, Kate; Guan, Shu-Hong; Tao, Si-Jia; Alan, Millar; Pang, Xiao-Yan; *Guo, De-An. Metabolites identification of ganoderic acid D by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry. Drug Metabolism and Disposition, 40(12), pp 2307-2314, 2012/12/16. 11. Cheng, Chun-Ru; *Yang, Min; Wu, Zhi-Yuan; Wang, Yang; Zeng, Feng; Wu, Wan-Ying; Guan, Shu-Hong; *Guo, De-An. Fragmentation pathways of oxygenated tetracyclic triterpenoids and their application in the qualitative analysis of Ganoderma lucidum by multistage tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 25(9), pp 1323-1335, 2011/3/9. 12. Cheng, Chun-Ru; Yue, Qing-Xi; Wu, Zhi-Yuan; Song, Xiao-Yi; Tao, Si-Jia; Wu, Xiao-Hui; Xu, Ping-Ping; Liu, Xuan; Guan, Shu-Hong; Guo, De-An. Cytotoxic triterpenoids from Ganoderma lucidum. Phytochemistry, 71(13), pp 1579-1585, 2010/06.