个人简介
教育经历
1980.9-1982.7 浙江省杭州化工学校化工机械专业（高中中专）
1988.9-1990.7 华东化工学院化学工程专业硕士研究生
1990.9-1993.7 华东理工大学化学工程专业博士研究生。
博士学位论文：杂交瘤细胞悬浮培养技术及其气升式生物反应器研究。
工作经历
1982.09-1988.07 浙江省桐乡农药厂，任技术员
1993.08-1995.08 华东理工大学生化工程研究所助理研究员
1995.09-1998.09 华东理工大学副教授，动物细胞与组织工程研究室主任
1997.04-1997.10 德国Bielefeld大学
1998.10-至今 华东理工大学教授，博士生导师（2000.03-至今），动物细胞与组织工程研究室主任
1996.09-2004.08 华东理工大学生化工程研究所所长
1998.07-2012.08 华东理工大学生物反应器工程国家重点实验室副主任
2006.09-2009.11 华东理工大学科技处副处长
2009.12-2015.09 华东理工大学工程教育学系系主任，兼高等教育研究所所长、理工优秀生部主任
2011.12-2015.12 华东理工大学学术委员会委员
2012.06-至今 生物反应器工程国家重点实验室学术委员会委员
2012.11-至今 华东理工大学海正研究院院长。
2014.11-至今 华东理工大学张江现代生物技术研究院院长
近期论文
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Min Chen, Yi Zhang, Yan Zhou, Yan Zhang, Meidong Lang, Zhaoyang Ye, Wen-Song Tan (2015) Pendant small functional groups on poly(?-caprolactone) substrate modulate adhesion, proliferation and differentiation of human mesenchymal stem cells. Colloids and Surfaces. B, Biointerfaces, 134: 322-331.
Feiyue Xu, Lei Xu, Qi Wang, Yan Zhou, Zhaoyang Ye, Wen-Song Tan (2015) A three-dimensional dynamic coculture system enabling facile cell separation for chondrogenesis of mesenchymal stem cells. Biochemical Engineering Journal, 103: 68-76.
Jintao Liu, Xinning Chen, Li Fan, Xiancun Deng, H. Fai Poon, Wen-Song Tan, Xuping Liu (2015) Monitoring sialylation levels of Fc-fusion protein using size-exclusion chromatography as a process analytical technology tool. Biotechnology Letters, 37(7): 1371-1377.
Xintao Zhang, Hongping Tang, Ya-Ting Sun, Xuping Liu, Wen-Song Tan, Li Fan (2015) Elucidating the effects of arginine and lysine on a monoclonal antibody C-terminal lysine variation in CHO cell cultures. Applied Microbiology and Biotechnology, 99(16): 6643-6652.
Xintao Zhang, Ya-Ting Sun, Hongping Tang, Li Fan, Dongdong Hu, Jintao Liu, Xuping Liu, Wen-Song Tan (2015) Culture temperature modulates monoclonal antibody charge variation distribution in Chinese hamster ovary cell cultures. Biotechnology Letters, 37(11): 2151-2157.
Dongdong Hu, Yating Sun, Xuping Liu, Jintao Liu, Xintao Zhang, Liang Zhao, Haibin Wang, Wen-Song Tan, Li Fan (2015) Understanding the intracellular effects of yeast extract on the enhancement of Fc-fusion protein production in Chinese hamster ovary cell culture. Applied Microbiology and Biotechnology, 99(20): 8429-8440.
Ding Huang, Wenjuan Peng, Qian Ye, Xuping Liu, Liang Zhao, Li Fan, Kang Xia-Hou, Hanjing Jia, Jian Luo, Linting Zhou, Beibei Li, Shilei Wang, Wenting Xu, Ze Chen, Wen-Song Tan (2015) Serum-free suspension culture of MDCK cells for production of influenza H1N1 vaccines. PLOS ONE, 10(11): e0141686.
Yaya Liu, Weiyan Zhang, Xiancun Deng, Hong Fai Poon, Xuping Liu, Wen-Song Tan, Yan Zhou, Li Fan (2015) Chinese hamster ovary cell performance enhanced by a rational divide-and-conquer strategy for chemically defined medium development. Journal of Bioscience and Bioengineering, 120(6): 690-696.
Xuping Liu, Ding Huang, Wen-Song Tan, Jian Luo, Ze Chen (2015) Overcoming nutrient limitations for cell-based production of influenza vaccine. Human Vaccines & Immunotherapeutics, 11(7): 1685-1688.
Zheng Du, Ziyan Wang, Weiwei Zhang, Haibo Cai, Wen-Song Tan (2015) Stem cell factor is essential for preserving NOD/SCID reconstitution capacity of ex vivo expanded cord blood CD34(+) cells. Cell Proliferation, 48(3): 293-300.
Feiyue Xu, Lei Xu, Qi Wang, Zhaoyang Ye, Yan Zhou, Wen-Song Tan (2014) 3D dynamic culture of rabbit articular chondrocytes encapsulated in alginate gel beads using spinner flasks for cartilage tissue regeneration. BioMed Research International, 2014:539789.
Maiqin Chen, Min Zhou, Zhaoyang Ye, Yan Zhou, Wen-Song Tan (2014) Ectopic osteogenesis of macroscopic tissue constructs assembled from human mesenchymal stem cell-laden microcarriers through in vitro perfusion culture. PLoS One, 9(10): e109214.
Xiu Wang, Qingling Jiao, Songjie Zhang, Zhaoyang Ye, Yan Zhou, Wen-Song Tan (2014) Perfusion culture-induced template-assisted assembling of cell-laden microcarriers is a promising route for fabricating macrotissues. Biotechnology Journal, 9(11): 1425-34.
Qingchun Zhang, Ke Tan, Yan Zhang, Zhaoyang Ye, Wen-Song Tan, Meidong Lang (2014) In situ controlled release of rhBMP-2 in gelatin-coated 3D porous poly(ε-caprolactone) scaffolds for homogeneous bone tissue formation. Biomacromolecules, 15 (1): 84–94.
Houyong Luo, Maiqin Chen, Xiu Wang, Yang Mei, Zhaoyang Ye, Yan Zhou, Wen-Song Tan (2014) Fabrication of viable centimeter-sized 3D tissue constructs with microchannel conduits for improved tissue properties through assembly of cell-laden microbeads. Journal of Tissue Engineering and Regenerative Medicine, 8(6): 493-504.
Bin Lei, Xu Zhang, Minglong Zhu, Wensong Tan (2014) Effect of fluid shear stress on catalytic activity of biopalladium nanoparticles produced by Klebsiella Pneumoniae ECU-15 on Cr(VI) reduction reaction. Bioresources and Bioprocessing, 1: 28.
Ding Huang, Kang Xia-Hou, Xu-Ping Liu, Liang Zhao, Li Fan, Zhaoyang Ye, Wen-Song Tan, Jian Luo, Ze Chen (2014) Rational design of medium supplementation strategy for improved influenza viruses production based on analyzing nutritional requirements of MDCK Cells. Vaccine, 52(32) : 7091–7097.
Jianyun Ge, Haibo Cai, Qunliang Li, Zheng Du, Wen-Song Tan (2013) Effects of telomerase activity and apoptosis on ex vivo expansion of cord blood CD34+ cells. Cell Proliferation, 46:38-44.
Qiang Jing , Haibo Cai, Zheng Du , Zhaoyang Ye & Wen-song Tan (2013) Effects of agitation speed on the ex vivo expansion of cord blood hematopoietic stem/progenitor cells in stirred suspension culture. Artificial Cells, Nanomedicine, and Biotechnology, 41(2): 98–102.
Qingchun Zhang, Yun Jiang, Yan Zhang, Zhaoyang Ye, Wen-Song Tan, Meidong Lang (2013) Effect of porosity on long-term degradation of poly (ε-caprolactone) scaffolds and their cellular response. Polymer Degradation and Stability, 98(1): 209-18.
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