个人简介

Ph.D.: University of Chicago, 1996 Postdoctoral Fellow: University of California, San Diego, 1997-1998 Senior Research Associate at The Scripps Research Institute, 1998-2003

研究领域

Bioanalytical Chemistry Molecular Biophysics Renewable Energy Biophysics Reaction Dynamics Physical

My interests are in molecular biophysics and optics for biotechnology. In one project, we employ femtosecond nonlinear electronic spectroscopy to investigate active-site dynamical asymmetry in heme proteins, protein-ligand interactions, and flexibility and conformational diversity in protein folding. Another area of my research involves selection strategies employing a microfluidic cellular spectroscopy and optical force-switching instrument for improving the photophysical properties of fluorescent proteins and sensors used in biological imaging.

近期论文

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E.A. Gibson and R. Jimenez “Three-pulse photon echo spectroscopy as a probe of flexibility and conformational heterogeneity in protein folding” Proceedings of the XVI International Conference on Ultrafast Phenomena (2008). J.D. Satterlee, C. Suquet, A.K. Bidwai, J.E. Erman, L. Schwall, R. Jimenez (2008) “Mass instability in isolated recombinant FixL heme domains of Bradyrhizobium Japonicum (BjFixLH)” Biochemistry 47, 1540-1553. W. Amir, D. N. Schafer, C. G. Durfee, J. A. Squier, E. A. Gibson, L. Kost, R. Jimenez (2008) “Linear spatio-temporal characterization of a UV microscope objective for nonlinear imaging and spectroscopy by using two-dimensional Spectral Interferometry,” Journal of Microscopy, 230 part 1, 4. D. Schafer, E.A. Gibson, W. Amir, R. Erickson, J. Lawrence, T. Vestad, J. Squier, R. Jimenez, D.W.M. Marr (2007) “Three-dimensional chemical concentration maps in a microfluidic device using two-photon absorption fluorescence imaging” Optics Letters 32, 2568. B. Cho, C.F. Carlsson, and R. Jimenez (2006) Photon echo spectroscopy of heme proteins and porphyrins: effects of quasi-degenerate electronic structure on the peak shift decay, J. Chem. Phys., 124, 144905. E.A. Gibson, D.M. Gaudiosi, H.C. Kapteyn, R. Jimenez, S. Kane, R. Huff, C. Durfee, and J. Squier (2006) Efficient reflection grisms for pulse compression and dispersion compensation of femtosecond pulses, Optics Letters, 31, 3363-5. T. Stiles, R. Fallon, T. Vestad, J. Oakey, D.W.M. Marr, J. Squier and R. Jimenez (2005) Hydrodynamic Focusing for vacuum-pumped microfluidics, Nanofluidics and Microfluidics, 1, 280-283