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个人简介

教育背景 2010年-2016年 加拿大多伦多大学生物材料与生物医学工程研究所 博士 2008年-2010年 加拿大多伦多大学机械工程系 硕士 2003年-2008年 加拿大多伦多大学工程科学-生物医学工程 本科 荣誉及奖励 2019年,国际生物医学工程会议年轻学者奖 2017年 国际肌肉骨骼研究协会联合会Travel Grant 2016年 美国骨与矿物研究学会青年研究员Travel Grant 2010-2014年 加拿大卫生研究院Travel Grant 2011-2013年 安大略省研究生奖学金 2008,2010年 芭芭拉和弗兰克米利根研究生奖学金

研究领域

干细胞力学生物学,骨组织工程及再生,功能性植入器械。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Chao Liu, Pamela Cabahug‐Zuckerman, Christopher Stubbs, Martin Pendola, Cinyee Cai, Kenneth A. Mann, and Alesha B. Castillo. "Mechanical loading promotes the expansion of primitive osteoprogenitors and organizes matrix and vascular morphology in long bone defects." Journal of Bone and Mineral Research (2019). e3668 In press 2. Chao Liu and Alesha B. Castillo. "Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair." JAAOS-Journal of the American Academy of Orthopaedic Surgeons 26.7 (2018): e153-e155. 3. Ma, Yu-Heng Vivian; Lam, Candy; Dalmia, Shreyash ; Gao, Peter; Young, Jacob; Middleton, Kevin; Liu, Chao; You, Lidan. “Mechanical regulation of breast cancer bone metastasis via direct and indirect osteocyte signalling in vitro” Journal of Cellular Biochemistry. 2018, 119 (7), 5665-5675 4. Chao Liu, Robert Carrera, Vittoria Flamini, Lena Kenny, Pamela Cabahug-Zuckerman, Benson George, Daniel Hunter, Bo Liu, Gurpreet Singh, Philipp Leucht, Kenneth A Mann, Jill A Helms, Alesha B Castillo, “Effects of mechanical loading on cortical defect repair using a novel mechanobiological model of bone healing” Bone. 2018, 108, pp. 145-155. 5. Qian, Weiyi; Gong, Lanqi; Cui, Xin; Zhang, Zijing; Bajpai, Apratim; Liu, Chao; Castillo, Alesha; Teo, Jeremy; Chen, Weiqiang “Nanotopographic regulation of human mesenchymal stem cell osteogenesis” ACS Applied Materials & Interfaces. 2017, 9 (48), pp 41794–41806 6. Bradaschia-Correa V, Josephson AM, Mehta D, Mizrahi M, Neibart SS, Liu C, Kennedy OD, Castillo AB, Egol KA, Leucht P. “The selective serotonin re-uptake inhibitor fluoxetine directly inhibits osteoblast differentiation and mineralization during fracture healing in mice.” Journal of Bone and Mineral Research. 32(4) 2017: 821–833 7. Chao Liu, Xin Cui, Thomas Michael Ackermann, Vittoria Flamini, Weiqiang Chen, Alesha Castillo “Osteoblast-Derived Paracrine Factors Regulate Angiogenesis in Response to Mechanical Stimulation” Integrative Biology 8(7) 2016, 785-794 8. Chao Liu, Xiaoqing Zhang, Michael Wu, Lidan You “Mechanical Regulation of Osteocyte Responses to Physical Damage in vitro” Journal of Biomechanics 2015. 48(16): 4221-4228 9. Ashutosh Parajuli*, Chao Liu*, Wen Li*, Xiaoyu Gu, Xiaohan Lai, Christopher Price, Lidan You, X. Lucas Lu, Liyun Wang “Bone's Responses to Mechanical Loading are Impaired in Type 1 Diabetes” Bone 81 (2015) 152–160. (*Equal contributions) 10. Jia-Ning Zhang, Yan Zhao, Chao Liu, Elizabeth S. Han, Xue Yu, Darcy Lidington, Steffen-Sebastian Bolz, Lidan You “The Role of the Sphingosine-1-Phosphate Signaling Pathway in Osteocyte Mechanotransduction Bone” Bone 79 (2015) 71-78. 11. Chao Wei, Beiyuan Fan, Deyong Chen, Chao Liu, Yuanchen Wei, Bo Huo, Lidan You, Junbo Wang and Jian Chen “Osteocyte Culture in Microfluidic Devices” Biomicrofluidics. 9, 014109 (2015) 12. Wing-Yee Cheung, Chao Liu, Craig A. Simmons, Lidan You, “Osteocyte Apoptosis is Mechanically Regulated and Induces Angiogenesis In Vitro”, Journal of Orthopedic Research, 2011 April ;29(4):523-30 13. Chao Liu, Yan Zhao, Wing-Yee Cheung, Ronak Gandhi, Liyun Wang, Lidan You “Effects of cyclic hydraulic pressure on osteocytes” Bone. 46 (5), May 2010, pp. 1449-1456 14. Chao Liu, Alesha B. Castillo, “Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair” Journal of the American Academy of Orthopaedic Surgeons. 2018 (invited review) 15. Jan-Hung Chen*, Chao Liu*, Lidan You, Craig A. Simmons, “Boning up on Wolff’s Law: Mechanical regulation of the cells that make and maintain bone” Journal of Biomechanics 43 (1), pp. 108-118 (*Equal contributions)

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