郑梅珍 - 南方科技大学

个人简介

工作经历 2019年 – 至今南方科技大学助理教授 2017年 – 2019年美国杰克逊实验室基因组医学中心副研究员 2012年 – 2017年美国杰克逊实验室基因组医学中心博士后 2010年 – 2012年新加坡基因组研究院博士后 2007年 – 2009年东华大学博士后学习经历 2004年 – 2007年中山大学附属肿瘤防治中心肿瘤学博士 2001年 – 2004年暨南大学医学院生物化学与分子生物学硕士 1995年 – 2001年华中科技大学同济医学院临床医疗学士

研究领域

1. 单细胞、单分子染色质交互作用技术研发及应用 2. 全基因组RNA-染色质DNA交互作用技术研发及应用 3. RNA介导的三维基因组空间结构及其转录调控机制

近期论文

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Meizhen Zheng, Simon Zhongyuan Tian, Daniel Capurso, Minji Kim, Rahul Maurya, Byoungkoo Lee, Emaly Piecuch, Liang Gong, Jacqueline Jufen Zhu, Zhihui Li, Chee Hong Wong, Chew Yee Ngan, Ping Wang, Xiaoan Ruan, Chia-Lin Wei & Yijun Ruan. Multiplex Chromatin Interaction Analysis with Single-Molecule Precision. Nature. 2019, 556:558-562. M.Z. Zheng, L.M. Zheng and Y.X. Zeng. SCC-112 gene is involved in tumor progression and promotes the cell proliferation in G2/M phase. J Cancer Res Clin Oncol. 2008 Apr; 134(4): 453-62. Meizhen Zheng, Haide Qin, Ruhua Zhang, Xingjuan Yu, Lizhen Chen, Qisheng Feng, Yixin Zeng. Haplotype of gene Nedd4 binding protein 2 associated with sporadic Nasopharyngeal carcinoma in the Southern Chinese population. J Transl Med. 2007 Jul 13; 5:36. Zheng, MZ; Jiang, JW. Progress in unmethylated immunostimulatory oligodeoxynucletides. Progress In Biochemistry And Biophysics. 2003, 30(2):190-193. The 4D nucleome project. The 4D Nucleome Network, Nature. 2017 Sep 13; 549 (7671): 219–226. Xingwang Li, Oscar Junhong Luo, Ping Wang, Meizhen Zheng, DanjuanWang, Emaly Piecuch, Jacqueline Jufen Zhu, Simon Zhongyuan Tian, Zhonghui Tang,Guoliang Li & Yijun Ruan. Long-read ChIA-PET for base-pair-resolution mapping of haplotype-specific chromatin interactions. Nature Protocol. 2017,12:899-915. Zhonghui Tang, Oscar Junhong Luo, Xingwang Li, Meizhen Zheng, Jacqueline Jufen Zhu, Przemyslaw Szalaj, Pawel Trzaskoma, Adriana Magalska, Jakub Wlodarczyk, Blazej Ruszczycki, Paul Michalski, Emaly Piecuch, Ping Wang, Danjuan Wang, Simon Zhongyuan Tian, May Penrad-Mobayed, Laurent M Sachs, Xiaoan Ruan, Chia-Lin Wei, Edison T Liu, Grzegorz M Wilczynski, Dariusz Plewczynski, Guoliang Li, Yijun Ruan. CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription. Cell. 2015, 163:1611-1627. Guoliang Li, X. Ruan, K. A. Raymond, K. S. Sandhu, Meizhen Zheng, Ping Wang, Huay Mei Poh, Yufen Goh, Joanne Lim, Jingyao Zhang, Hui Shan Sim, Su Qin Peh, Fabianus Hendriyan Mulawadi, Chin Thing Ong, Yuriy L. Orlov, Shuzhen Hong, Zhizhuo Zhang, Steve Landt, Debasish Raha, Ghia Euskirchen, Chia-Lin Wei, Weihong Ge, Huaien Wang, Carrie Davis, Katherine Fisher, Ali Mortazavi, Mark Gerstein, Thomas Gingeras, Barbara Wold, Yi Sun, Melissa J. Fullwood, Edwin Cheung, Edison Liu, Wing-Kin Sung, Michael Snyder, Yijun Ruan. Extensive Promoter-centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation. Cell. 2012 Jan 20;148 (1- 2):84-98. ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012 Sep 6; 489(7414): 57-74.