个人简介
工作经历
2018 – 至今 南方科技大学生物系 助理教授
2016 – 2017年 复旦大学脑科学研究院 副研究员
2013 – 2016年 哈佛大学医学院 博士后
2009 – 2013年 复旦大学脑科学研究院 助理研究员
学习经历
2005 – 2009年 复旦大学 神经生物学专业 博士
2002 – 2005年 皖南医学院 生理学专业 硕士
1997 – 2002年 皖南医学院 临床医学专业 学士
研究领域
慢性疼痛的脊髓上行投射和脑干下行调控神经环路
阿片受体镇痛、引起疼痛敏化和镇痛耐受的神经环路机制
头面部痛引起躯体痛的神经环路机制
长期社交隔离(SIS)引起躯体痛的神经环路机制
镜像痛(MIP)的神经环路机制
近期论文
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1.Cheng L*, Duan B*, Huang T*, Zhang Y, Chen Y, Britz O, Garcia-Campmany L, Ren X, Vong L, Lowell BB, Goulding M, Wang Y#, Ma Q#. Identification of spinal circuits involved in touch-evoked dynamic mechanical pain. Nature Neuroscience 2017, 20(6):804-8014 (*Co-first author)
2.Duan B*, Cheng L*, Bourane S, Britz O, Padilla C, Garcia-Campmany L, Krashes M, Knowlton W, Velasquez T, Ren X, Ross SE, Lowell BB, Wang Y, Goulding M*, Ma Q*. Identification of spinal circuits transmitting and gating mechanical pain. Cell 2014, 159(6):1417-32 (*Co-first author)
3.Duan B#, Cheng L#, Ma Q#. Spinal circuits transmitting mechanical pain and itch. Neuroscience Bulletin 2017, Epub 2017 May 08 (#Co-corresponding author)
4.Bourane S*, Duan B*, Koch S, Dalet A, Britz A, Garcia-Campmany L, Kim E, Cheng L, Ghosh A, Ma Q#, Goulding M#. Gate control of mechanical itch by a subpopulation of spinal cord interneurons. Science 2015, 350(6260):550-4
5.Li WW*, Cheng L*, Zou Z, Tian ML, Zhang H, Raya AD, Wang Y#, Shi XY#. (R)-alpha-methylhistamine Suppresses Inhibitory Neurotransmission in Hippocampal CA1 Pyramidal Neurons Counteracting Propofol-Induced Amnesia in Rats. CNS Neuroscience & Therapeutics 2014, 20: 851-859 (*Co-first author)
6.Wan L, Liu X, Wu Z, Ren WT, Kong SZ, Abou Dargham R, Cheng L#, Wang Y#. Activation of extrasynaptic GABA(A) receptors inhibits cyclothiazide-induced epileptiform activity in hippocampal CA1 neurons. Neuroscience Bulletin 2014, 30: 866-876 (#Co-corresponding author)
7.Lü N, Cheng L, Zhang YQ, Lü BC, Li YQ, Zhao ZQ#. Involvement of ryanodine receptors in tetanic sciatic stimulation-induced long term potentiation of spinal dorsal horn and persistent pain in rats. Journal of Neuroscience Research. Journal of Neuroscience Research 2012, 90: 1096-1104.
8.Chen ML*, Cao H*, Chu YY, Cheng L, Liang LL, Zhao ZQ#. Role of P2X7 Receptor-Mediated IL-18/IL-18R Signaling in Morphine Tolerance: Multiple Glial-Neuronal Dialogues in the Rat Spinal Cord. Journal of Pain 2012, 13, 945-958
9.Li TT*, Ren WH*, Xiao X*, Nan J, Cheng L, Zhang XH, Zhao ZQ, Zhang YQ#. Role of P2X7 Receptor-Mediated IL-18/IL-18R Signaling in Morphine Tolerance: Multiple Glial-Neuronal Dialogues in the Rat Spinal Cord. Journal of Pain 2012, 13, 945-958
10.Cheng L*, Han L*, Fan J, Huang LT, Peng LC, Wang Y#. Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559. Molecular Pain 2011, 7:13 (*Co-first author)
11.Cheng L*, Lü N*, Zhang YQ, Zhao ZQ#. Ryanodine receptors contribute to the induction of nociceptive input-evoked long-term potentiation in the rat spinal cord slice. Molecular Pain 2010, 6:1. (*Co-first author)