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个人简介

教育经历 2017 香港浸会大学 哲学博士 质谱分析 导师:蔡宗苇教授 2010 南京中医药大学 医学硕士 中药学 导师:吴皓教授 2007 河南大学 理学学士 药学 工作经历 2019-今 南方科技大学 前沿与交叉科学研究院 研究助理教授(副研究员) 2018-2019 南方科技大学 前沿与交叉科学研究院 高级研究助理(助理研究员) 2011-2013 深圳华大基因研究院 实验室主管、代谢组学平台负责人 2010-2011 深圳华大基因研究院 研究助理

研究领域

质谱分析,定量代谢组学,高通量临床代谢组学和蛋白质组学技术开发,及其在衰老/神经退行性疾病的应用等

近期论文

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Luan H.; Ji F.; Chen Y.; Cai Z., statTarget: A streamlined tool for signal drift correction and interpretations of quantitative mass spectrometry-based omics data. Analytica Chimica Acta 2018, DIO: https://doi.org/10.1016/j.aca.2018.08.002 Luan H.; Ji F.; Chen Y.; Cai Z., Quality control-based signal drift correction and interpretations of metabolomics/proteomics data using random forest regression. bioRxiv. 2018, 253583 DIO: https://doi.org/10.1101/253583 Luan, H.; Xian Wang; Zongwei Cai, Mass spectrometry-based metabolomics: Targeting the crosstalk between gut microbiota and brain in neurodegenerative disorders. Mass Spectrometry Reviews 2019, DIO: 10.1002/mas.21553 Luan, H.; Meng, N.; Liu, P.; Fu, J.; Chen, X.; Rao, W.; Jiang, H.; Xu, X.; Cai, Z.; Wang, J., Non-targeted metabolomics and lipidomics LC-MS data from maternal plasma of 180 healthy pregnant women. Gigascience 2015, 4, 16. Luan, H.; Liu, L.; Tang, Z.; Zhang, M.; Chua, K.; Song, J.; Mok, V.; Li, M.; Cai, Z.,Comprehensive urinary metabolomic profiling and identification of potential noninvasive marker for idiopathic Parkinson's disease. Rep. 2015, 5, 13888. Luan, H.; Meng, N.; Liu, P.; Feng, Q.; Lin, S.; Fu, J.; Davidson, R.; Chen, X.; Rao, W.; Chen, F.; Jiang, H.; Xu, X.; Cai, Z.; Wang, J., Pregnancy-induced metabolic phenotype variations in maternal plasma. J Proteome Res 2014, 13, (3), 1527-36. Luan, H.; Liu, L. F.; Meng, N.; Tang, Z.; Chua, K. K.; Chen, L. L.; Song, J. X.; Mok, V. C.; Xie, L. X.; Li, M.; Cai, Z., LC-MS-Based Urinary Metabolite Signatures in Idiopathic Parkinson's Disease. J Proteome Res 2014. 14(1):467-78. Luan, H.; Liu, L.; Tang, Z.; Mok, V.; Li, M.; Cai, Z., Elevated excretion of biopyrrin as a new marker for idiopathic Parkinson's disease, Parkinsonism & Related Disorders, 2015, DIO: 10.1016/j.parkreldis.2015.09.009. Luan, H., Chen, L., Ji, F., Cai, Z., PCI-GC-MS-MS approach for identification of non-amino organic acid and amino acid profiles. Journal of Chromatography B 2016, DIO: doi:10.1016/j.jchromb.2016.06.034 Luan, H.; Meng, N.; Fu, J.; Chen, X.; Xu, X.; Feng, Q.; Jiang, H.; Dai, J.; Yuan, X.; Lu, Y.; Roberts, A. A.; Luo, X.; Chen, M.; Xu, S.; Li, J.; Hamilton, C. J.; Fang, C.; Wang, J., Genome-wide transcriptome and antioxidant analyses on gamma-irradiated phases of deinococcus radiodurans R1. PLoS One 2014, 9, (1), e85649. Luan, H.; Chen, X.; Zhong, S.; Yuan, X.; Meng, N.; Zhang, J.; Fu, J.; Xu, R.; Lee, C.; Song, S.; Jiang, H.; Xu, X., Serum metabolomics reveals lipid metabolism variation between coronary artery disease and congestive heart failure: a pilot study. Biomarkers 2013, 18, (4), 314-21. Luan, H. M.; Wang, L. C.; Wu, H.; Jin, Y.; Ji, J., Antioxidant activities and antioxidative components in the surf clam, Mactra veneriformis. Nat Prod Res 2011, 25, (19), 1838-48. Li Xiang, Hongsong Zhang, Juntong Wei, Xiao Yu Tian, Hemi Luan, Shangfu Li, Hongzhi Zhao, Guodong Cao, Arthur C.K. Chung, Chunxue Yang, Yu Huang, Zongwei Cai, Metabolomics studies on db/db diabetic mice in skeletal muscle reveal effective clearance of overloaded intermediates by exercise, Analytica Chimica Acta, 2017, DIO: https://doi.org/10.1016/j.aca.2017.11.082 F Ji, H Luan, Y Huang, Z Cai, M Li; MS-Based Metabolomics for the Investigation of Neuro-Metabolic Changes Associated with BDE-47 Exposure in C57BL/6 Mice. Journal of Analysis and Testing, 2017, 1(3): 233-244. Qin, C.; Yu, C.; Shen, Y.; Fang, X.; Chen, L.; Min, J.; …; Luan, H.; et. al, Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization. Proc Natl Acad Sci U S A 2014, 111, (14), 5135-40. Yang L., Li J., Lai J, Luan H., Cai Z., Wang Y., Zhao Y. and Wu Y., Placental transfer of perfluoroalkyl substances and associations with thyroid hormones: Beijing prenatal exposure study. Rep. 2016, 6, 21699. Wang, S., Chen, X., Luan, H., Gao, D., Lin, S., Cai, Z., Liu, J., Liu, H., and Jiang, Y. Matrix-assisted laser desorption/ionization mass spectrometry imaging of cell cultures for the lipidomic analysis of potential lipid markers in human breast cancer invasion. Rapid Commun. Mass Spectrom. 2016, 30: 533–42.

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