Lockyer, Nicholas - University of Manchester - School of Chemical Engineering and Analytical Science

个人简介

I am a Reader (Associate Professor) in the School of Chemistry, Analytical Measurement and Physical Chemistry Section. My first degree and PhD were from the Department of Chemistry at UMIST. On completion of my PhD I took up a post-doc with Prof John Vickerman to develop a new imaging ToF-SIMS (secondary ion mass spectrometry) instrument for surface chemical analysis. Further development work and biological applications of ToF-SIMS were pursued through a Leverhulme Special Research Fellowship. I joined the School of Chemical Engineering and Analytical Science on the creation of the new University of Manchester in 2004, transferring to the School of Chemistry in 2011

研究领域

My research interests focus on the development and application of surface analysis and chemical imaging particularly ToF-SIMS and laser-based mass spectrometry. There are three themes to our research: fundamentals, instrument development and applications research. The Life Sciences provide an exciting field in which to develop new applications, which in turn drive the development in these areas. Together with the Vickerman group we are currently seeking to exploit these advances through a variety of collaborations with fellow academics, industrial partners and healthcare professionals. Research topics: Analytical Chemistry; Instrumentation; Chemical imaging; Ion-solid interactions; Laser-matter interactions.

近期论文

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Mcnamara, M. E., van Dongen, B. E., Lockyer, N. P., Bull, I. D. & Orr, P. J. 1 May 2016 In : Palaeontology. 59, 3, p. 337-350 14 p.Research output: Contribution to journal ? ArticleDOI: 10.1111/pala.12238 Peptide Fragmentation and Surface Structural Analysis by Means of ToF-SIMS Using Large Cluster Ion SourcesYokoyama, Y., Aoyagi, S., Fujii, M., Matsuo, J., Fletcher, J. S., Lockyer, N. P., Vickerman, J. C., Passarelli, M. K., Havelund, R. & Seah, M. P. 19 Apr 2016 In : Analytical Chemistry. 88, 7, p. 3592-3597 6 p.Research output: Contribution to journal ? ArticleDOI: 10.1021/acs.analchem.5b04133 Evaluation of biomolecular distributions in rat brain tissues by means of ToF-SIMS using a continuous beam of Ar clustersNakano, S., Yokoyama, Y., Aoyagi, S., Himi, N., Fletcher, J. S., Lockyer, N. P., Henderson, A. & Vickerman, J. C. 8 Jan 2016 In : Biointerphases. 11, p. 02A307 5 p.Research output: Contribution to journal ? ArticleDOI: 10.1116/1.4939251 Matrix Effects in Biological SIMS using Cluster Ion Beams of Different Chemical CompositionAlnajeebi, A., Vickerman, J. C. & Lockyer, N. P. 2016 In : Biointerphases. 11, 2Research output: Contribution to journal ? ArticleDOI: 10.1116/1.4941009