刘凌峰 - 复旦大学 - 生命科学学院

个人简介

1998.09~2003.06 复旦大学上海医学院/公共卫生学院预防医学专业医学学士 2003.09~2008.07 复旦大学生命科学学院/遗传学研究所/遗传工程国家重点实验室哲学博士 2008.10~2011.12 美国弗莱德.哈钦森癌症研究中心基础医学研究部博士后 2012.01~2017.07 美国弗莱德.哈钦森癌症研究中心临床医学研究部助理研究员 2017.08~2018.08 美国华盛顿大学医学中心访问学者/教授 2017.08~至今福建医科大学附属协和医院教授 2018.09~至今复旦大学生命科学学院/复旦大学人类表型组研究院青年研究员/博士生导师 2018.09~至今复旦大学附属中山医院客座教授

研究领域

精准医学领域：免疫细胞治疗，细胞工程设计及免疫细胞表型研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Liu L & Riddell SR; Tagged chimeric effector molecules and receptors thereof. Publication number WO2015095895 A1; Application number PCT/US2014/072007 Liu L, Riddell SR & Hoffstrom BG Development of high-affinity Strep-tag II monoclonal antibodies for multiple functionalities and use with genetically modified cells. (Serial NO: 62/555,017/US Filing date: 9/6/2017) Liu L, Riddell SR, Busch DH & Fr??le SP Development of chimeric receptors that are specific for strep-tag II and uses thereof (Serial NO: 62/555,012/US Filing date: 9/6/2017) Liu L, Sommermeyer D, Cabanov A, Kosasih P, Hill T, Riddell SR Inclusion of Strep-tag II in design of antigen receptors for T-cell immunotherapy. Nature Biotechnology. 2016 Apr;34(4):430-4. F1000Prime ? Article Recommendations Liu L & Eisenman RN., Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A Glycogen Synthase Kinase 3 Negative Feedback Pathway, Genes & Cancer. 2012 Jan;3(1):23-36 Salter AI, Ivey RG, Kennedy JJ, Voillet V, Rajan A, Alderman EJ, Voytovich UJ, Lin C, Sommermeyer D, Liu L, Whiteaker JR, Gottardo R, Paulovich AG, Riddell SR Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function. Science Signaling. 2018 Aug 21;11(544) Paszkiewicz PJ, Fr??le SP, Srivastava S, Sommermeyer D, Hudecek M, Drexler I, Sadelain M, Liu L, Jensen MC, Riddell SR, Busch DH. Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia. J Clin Invest. 2016 Nov 1; 126 (11):4262-4272. Michael Hudecek?, Daniel Sommermeyer?, Paula L. Kosasih, Anne Silva, Lingfeng Liu, Christoph Rader, Michael C. Jensen, Stanley R. Riddell The non-signaling extracellular spacer domain of CD19- specific chimeric antigen receptors is decisive for in vivo antitumor activity. Cancer Immunol Res. 2015 Feb;3(2):125-35 Riddell SR, Sommermeyer D, Berger C, Liu Lingfeng, Balakrishnan A, Salter A, Hudecek M, Maloney DG, Turtle CJ, Adoptive therapy with chimeric antigen receptor-modified T cells of defined subset composition. Cancer J. 2014 Mar-Apr; 20(2):141-4