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个人简介

教育工作经历 博士,副教授。2002-2007年就读于复旦大学生命科学学院,获得理学博士学位。2007-2009年在复旦大学医学院从事博士后研究。2009年-至今在复旦大学生命科学学院任讲师、副教授 科研项目(在研) 国家自然科学基金面上项目,81971900 ,PPE57通过促进结核杆菌脂质TMM转运调控宿主细胞脂滴形成和细菌持留的作用机制研究 ,2020/01-2024/12,55万元 国家科技重大专项项目,2018ZX10731301-004-001,增强型重组卡介苗的研究,2018/01-2021/9,287.68万元 国家科技重大专项项目,2018ZX10302302-002-002,针对卡介苗免疫后潜伏感染人群结核病疫苗的研制,2018/01-2021/9,291.22万元 获奖情况 2015年获上海市科技进步奖三等奖

研究领域

结核分枝杆菌的感染与免疫;新型结核病疫苗的研制

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Haibo Su, Zhongping Liang, ShuFeng Weng, Chaonan Sun, Jiaxin Huang, TianRan Zhang, Xialian Wang, Shanshan Wu, Qing Gong, Ying Xu*. MiR-9-5p Regulates Immunometabolic and Epigenetic Pathways in β-glucan-Trained Immunity via IDH3α. JCI insight. 2021, Accecpt. Su H, Zhang Z, Liu Z, Peng B, Kong C, Wang H, Zhang Z, Xu Y*. Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells. J Biol Chem. 2018. 293(26):10287-10302. Liulin Luo, Lin Zhu, Jun Yue, Jianping Liu, Guoyuan Liu, Xuelian Zhang, Honghai Wang,and Ying Xu*. Antigens Rv0310c and Rv1255c are promising novel biomarkers for the diagnosis of Mycobacterium tuberculosis infection. Emerging Microbes & Infections 2017, 6, e64. Haibo Su, Shengling Zhu, Lin Zhu, Cong Kong, Qi Huang, Zhi Zhang, Honghai Wang and Ying Xu*. Mycobacterium tuberculosis Latent Antigen Rv2029c from the Multistage DNA Vaccine A39 Drives TH1 Responses via TLR-mediated Macrophage Activation. Frontiers in Microbiology 2017. 8,2266. Su H, Zhu S, Zhu L, Huang W, Wang H, Zhang Z, Xu Y*. Recombinant Lipoprotein Rv1016c Derived from Mycobacterium tuberculosis Is a TLR-2 Ligand that Induces Macrophages Apoptosis and Inhibits MHC II Antigen Processing. Front Cell Infect Microbiol.2016. 18;6:147. Haibo Su, Cong Kong, Lin Zhu, Qi Huang, Liulin Luo, Honghai Wang and Ying Xu*. PPE26 induces TLR2-dependent activation of macrophages and drives Th1-type T-cell immunity by triggering the cross-talk of multiple pathways involved in the host response.Oncotarget.2015. 6(36):38517-37. Li G, Liu G, Song N, Kong C, Huang Q, Su H, Bi A, Luo L, Zhu L, Xu Y*, Wang H.. A novel recombinant BCG-expressing pro-apoptotic protein BAX enhances Th1 protective immune responses in mice. Mol Immunol. 2015. 66(2):346-356. Xu Y, Yang E, Huang Q, Ni W, Kong C, Liu G, Li G, Su H, Wang H. PPE57 induces activation of macrophages and drives Th1-type immune responses through TLR2. J Mol Med (Berl). 2015. Jan 15.

学术兼职

中国疫苗行业协会核酸疫苗分会委员,中华医学会结核分会基础专委会委员,上海医学会结核病分会青年委员

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