陆晨琪 - 复旦大学 - 生命科学学院

个人简介

1999-2003年就读于复旦大学生命科学学院生物科学专业，获学士学位；2003-2008年就读于复旦大学生命科学学院遗传学专业硕博连读，获博士学位；2008-2012年进入复旦大学数理科技创新平台任助理研究员，期间2011-2012年赴英国伯明翰大学生命科学系进行学术访问；2012年进入复旦大学生命科学学院，2017年晋升副教授。主持国家自然科学基金青年项目和2个面上项目。

研究领域

生物复杂网络拓扑结构研究（模块结构分析和网络演化模型）；整合高通量组学数据，研究疾病发生发展的非编码RNA等表观遗传机制。主要从事细胞重编程和干细胞分化等细胞命运决定中的转录组和表观遗传组学分析，揭示了非编码RNA等表观遗传因素在细胞命运决定中的表观遗传调控网络

近期论文

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Xiaoqin Liu, Yiwei Yang, Xing Wang, Xudong Guo, Chenqi Lu*, Jiuhong Kang*, Guiying Wang*. MiR-184 directly targets Wnt3 in cardiac mesoderm differentiation of embryonic stem cells. Stem Cell 2020;1–10. DOI: 10.1002/stem.3282; Xuelian Shao, Yu Fu, Jinmin Ma, Xueyu Li, Chenqi Lu*, Ruilin Zhang*. Functional Alterations and Transcriptomic Changes During Zebrafish Cardiac Aging. Biogerontology. 2020 21:637–652; Guiying Wang, Jun Yu, Yiwei Yang, Xiaoqin Liu, Xiaobo Zhao, Xudong Guo, Tao Duan, Chenqi Lu*, Jiuhong Kang*. Whole-transcriptome sequencing uncovers core regulatory modules and gene signatures of human fetal growth restriction. Clinical and Translational Medicine. 2020. 9:9; Yuanyuan Lan, Chenqi Lu#, Yiwei Yang, Xiaoqin Liu, Xudong Guo, Jiajie Xi, Jiuhong Kang*, Guiying Wang*. Linc1557 Is Critical for the Initiation of Embryonic Stem Cell Differentiation by Directly Targeting the LIF/STAT3 Signaling Pathway. Stem Cells. 2020 38(3):340-351; Rong Weng#, Chenqi Lu#, Xiaoqin Liu, Guoping Li, Yuanyuan Lan, Jing Qiao, Mingliang Bai, Zhaojie Wang, Xudong Guo, Dan Ye, Zeyidan Jiapaer, Yiwei Yang, Chenliang Xia, Guiying Wang*, Jiuhong Kang*. Long noncoding RNA-1604 orchestrates neural differentiation through the miR-200c/ZEB axis. Stem Cells 2018 36(3):325-336; Guiying Wang, Rong Weng, Yuanyuan Lan, Xudong Guo, Qidong Liu, Xiaoqin Liu, Chenqi Lu*, Jiuhong Kang*. Synergetic effects of DNA methylation and histone modification during mouse induced pluripotent stem cell generation. Scientific Reports 2017 7:39527; Gao, Xiang; Sun, Jingping; Huang, Chunyu; Hu, Xiaohua*; Jiang, Ning*; Lu, Chenqi*. RNAi-mediated silencing of NOX4 inhibited the invasion of gastric cancer cells through JAK2/STAT3 signaling. American Journal of Translational Research 2017 9(10): 4440-4449; Lu, Chenqi; Liu, Xiaoqin; Wang, Lin; Jiang, Ning; Yu, Jun; Zhao, Xiaobo; Hu, Hairong; Zheng, Saihua; Li, Xuelian*; Wang, Guiying*. Integrated analyses for genetic markers of polycystic ovary syndrome with 9 case-control studies of gene expression profiles. Oncotarget 2017 8(2) :3170-3180;